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Experimental infection of cattle with SARS-CoV-2

By Lorenz Ulrich, Kerstin Wernike, Donata Hoffmann, Thomas C. Mettenleiter, Martin Beer

Posted 25 Aug 2020
bioRxiv DOI: 10.1101/2020.08.25.254474 (published DOI: 10.3201/eid2612.203799)

Six cattle (Bos taurus) were intranasally inoculated with SARS-CoV-2 and kept together with three naive in-contact animals. Low-level virus replication and a specific sero-reactivity were observed in two inoculated animals, despite the presence of high antibody titers against a bovine betacoronavirus. The in-contact animals did not become infected. ### Competing Interest Statement The authors have declared no competing interest.

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