Rxivist logo

Phylogenetic Analysis of SARS-CoV-2 Genomes in Turkey

By Ogun Adebali, Aylin Bırcan, Defne Çırcı, Burak İşlek, Zeynep Kilinç, Berkay Selçuk, Berk Turhan

Posted 15 May 2020
bioRxiv DOI: 10.1101/2020.05.15.095794 (published DOI: 10.3906/biy-2005-35)

COVID-19 has effectively spread worldwide. As of May 2020, Turkey is among the top ten countries with the most cases. A comprehensive genomic characterization of the virus isolates in Turkey is yet to be carried out. Here, we built a phylogenetic tree with globally obtained 15,277 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes. We identified the subtypes based on the phylogenetic clustering in comparison with the previously annotated classifications. We performed a phylogenetic analysis of the first thirty SARS-CoV-2 genomes isolated and sequenced in Turkey. We suggest that the first introduction of the virus to the country is earlier than the first reported case of infection. Virus genomes isolated from Turkey are dispersed among most types in the phylogenetic tree. We find two of the seventeen sub-clusters enriched with the isolates of Turkey, which likely have spread expansively in the country. Finally, we traced virus genomes based on their phylogenetic placements. This analysis suggested multiple independent international introductions of the virus and revealed a hub for the inland transmission. We released a web application to track the global and interprovincial virus spread of the isolates from Turkey in comparison to thousands of genomes worldwide. ### Competing Interest Statement The authors have declared no competing interest.

Download data

  • Downloaded 2,888 times
  • Download rankings, all-time:
    • Site-wide: 1,970 out of 89,211
    • In genomics: 393 out of 5,693
  • Year to date:
    • Site-wide: 363 out of 89,211
  • Since beginning of last month:
    • Site-wide: 600 out of 89,211

Altmetric data


Downloads over time

Distribution of downloads per paper, site-wide


PanLingua

Sign up for the Rxivist weekly newsletter! (Click here for more details.)


News