Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 73,343 bioRxiv papers from 319,280 authors.

Studies of opsin genes offer insights into the evolutionary history and molecular basis of vertebrate color vision, but most assume intact open reading frames equate to functional phenotypes. Despite known variation in opsin repertoires and associated visual phenotypes, the genetic basis of such patterns has not been examined at each step of the central dogma. By comparing sequences, gene expression, and protein localization across a hyperdiverse group of mammals, noctilionoid bats, we find evidence that independent losses of S-opsin arose through disruptions at different stages of protein synthesis, while maintenance relates to frugivory. Discordance between DNA, RNA, and protein reveals that the loss of short-wave sensitivity in some lineages resulted from transcriptional and post-transcriptional changes in addition to degradation of open reading frames. These mismatches imply that visual phenotypes cannot reliably be predicted from genotypes alone, and connect ecology to multiple mechanisms behind the loss of color in vertebrates.

Download data

• Downloaded 567 times
• Download rankings, all-time:
  • Site-wide: 20,253 out of 73,343
  • In genomics: 2,359 out of 4,869
• Year to date:
  • Site-wide: 44,249 out of 73,343
• Since beginning of last month:
  • Site-wide: 44,240 out of 73,343

Altmetric data

Downloads over time

Distribution of downloads per paper, site-wide