Rxivist logo

Exploring the Links between Specific Depression Symptoms and Brain Structure: A Network Study

By Eva Hilland, Nils Inge Landrø, Brage Kraft, Christian K Tamnes, Eiko I. Fried, Luigi A. Maglanoc, Rune Jonassen

Posted 16 Sep 2019
bioRxiv DOI: 10.1101/762609 (published DOI: 10.1111/pcn.12969)

The network approach to psychopathology has recently received considerable attention, and is as a novel way of conceptualizing mental disorders as causally interacting symptoms. In this study, we modeled a joint network of depression symptoms and depression-related brain structures, using 21 symptoms and five regional brain measures. We used a mixed sample of 268 individuals previously treated for one or more major depressive episodes and never depressed individuals. The network revealed associations between brain structure and unique depressive symptoms, which may clarify relationships regarding symptomatic and biological heterogeneity in depression.

Download data

  • Downloaded 434 times
  • Download rankings, all-time:
    • Site-wide: 54,697
    • In neuroscience: 8,327
  • Year to date:
    • Site-wide: 93,319
  • Since beginning of last month:
    • Site-wide: 71,156

Altmetric data


Downloads over time

Distribution of downloads per paper, site-wide


PanLingua

Sign up for the Rxivist weekly newsletter! (Click here for more details.)


News