Rxivist logo

Meta-16S rRNA gene phylogenetic reconstruction reveals astonishing diversity of the cosmopolitan myxobacteria

By Yang Liu, Qing Yao, Hong-Hui Zhu

Posted 04 Sep 2019
bioRxiv DOI: 10.1101/754119 (published DOI: 10.3390/microorganisms7110551)

Numerous ecological studies for myxobacteria have been conducted well, but their true diversity hidden in plain sight remains to be explored. To bridge this gap, we here implemented a comprehensive survey of diversity and distribution of myxobacteria by using 4997 publicly available 16S rRNA gene sequences (≥1200 bp) collected from several hundreds of sites across multiple countries and regions. In the study, the meta-16S rRNA gene phylogenetic reconstruction clearly revealed that these sequences were classified to 998 species, 445 genera, 58 families, and 20 suborders, highlighting a considerable taxonomic diversity of myxobacteria, the great majority of which belonged to new taxa. Most cultured myxobacteria including the well-described type strains were strongly inclined to locate on the shallow branches of the phylogenetic tree; on the contrary, the majority of uncultured myxobacteria the deep branches. The geographical analysis of sequences based on their environmental categories clearly demonstrated that myxobacteria showed a nearly cosmopolitan distribution, despite the presence of some habitat-specific taxa, especially at genus and species levels. Among all abundant suborders, members of Suborder\_4, Suborder\_15, and Suborder_17 were more widely distributed in marine environments, the remaining suborders preferred to reside in terrestrial ecosystems, particularly in soils, indicating a potential selectivity of geographical distribution. In conclusion, this study profiles a clear framework of diversity and distribution of the cosmopolitan myxobacteria and sheds light on the isolation of the uncultured myxobacteria.

Download data

  • Downloaded 204 times
  • Download rankings, all-time:
    • Site-wide: 96,612
    • In microbiology: 7,164
  • Year to date:
    • Site-wide: 29,515
  • Since beginning of last month:
    • Site-wide: 73,236

Altmetric data

Downloads over time

Distribution of downloads per paper, site-wide


Sign up for the Rxivist weekly newsletter! (Click here for more details.)