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powsimR: Power analysis for bulk and single cell RNA-seq experiments

By Beate Vieth, Christoph Ziegenhain, Swati Parekh, Wolfgang Enard, Ines Hellmann

Posted 15 Mar 2017
bioRxiv DOI: 10.1101/117150 (published DOI: 10.1093/bioinformatics/btx435)

Power analysis is essential to optimize the design of RNA-seq experiments and to assess and compare the power to detect differentially expressed genes in RNA-seq data. PowsimR is a flexible tool to simulate and evaluate differential expression from bulk and especially single-cell RNA-seq data making it suitable for a priori and posterior power analyses.

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