Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 65,436 bioRxiv papers from 289,855 authors.
Transcripts are frequently modified by structural variations, which leads to a fused transcript of either multiple genes (known as a fusion gene) or a gene and a previously non-transcribing sequence. Detecting these modifications (called transcriptomic structural variations, or TSVs), especially in cancer tumor sequencing, is an important and challenging computational problem. We introduce SQUID, a novel algorithm to accurately predict both fusion-gene and non-fusion-gene TSVs from RNA-seq alignments. SQUID unifies both concordant and discordant read alignments into one model, and doubles the accuracy on simulation data compared to other approaches. With SQUID, we identified novel non-fusion-gene TSVs on TCGA samples.
- Downloaded 1,622 times
- Download rankings, all-time:
- Site-wide: 3,344 out of 65,436
- In bioinformatics: 672 out of 6,486
- Year to date:
- Site-wide: 20,177 out of 65,436
- Since beginning of last month:
- Site-wide: 15,129 out of 65,436
Downloads over time
Distribution of downloads per paper, site-wide
- Top preprints of 2018
- Paper search
- Author leaderboards
- Overall metrics
- The API
- Email newsletter
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!