Rxivist logo

Novitski's distal shift in paracentric inversion evolution

By Spencer A. Koury

Posted 03 Dec 2018
bioRxiv DOI: 10.1101/485334

In Drosophila pseudoobscura younger chromosomal inversions tend to be found distal to older inversions. By examining phylogenetic series of overlapping inversions for 134 gene arrangements of 13 chromosomes this pattern was extended to five additional Drosophila species. This distinct pattern arose repeatedly and independently in all six species and likely reflects an underlying principle of chromosome evolution. In this study it is illustrated how transmission of distal inversions is always favored in female meiosis when crossing over in homosequential regions of overlapping inversions generates asymmetric dyads. This cytogenetic mechanism for female meiotic drive is described in detail and advanced as an explanation for the distal shift in phylogenetic series of overlapping inversions as well as several better known patterns in the evolution of serially inverted chromosomes.

Download data

  • Downloaded 138 times
  • Download rankings, all-time:
    • Site-wide: 78,614 out of 88,877
    • In evolutionary biology: 4,987 out of 5,438
  • Year to date:
    • Site-wide: 78,884 out of 88,877
  • Since beginning of last month:
    • Site-wide: 65,891 out of 88,877

Altmetric data

Downloads over time

Distribution of downloads per paper, site-wide


Sign up for the Rxivist weekly newsletter! (Click here for more details.)