Rxivist logo

Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 65,454 bioRxiv papers from 289,944 authors.

Williams et al. (Nat. Genet. 48:238-224, 2016) recently reported neutral tumor evolution in one third of 904 samples from The Cancer Genome Atlas. Here, we assess the reproducibility and validity of their method and the extent of positive selection in subclonal mutations across cancer types. Our results do not support observable neutral tumor evolution and uncover strong positive selection within subclonal mutations across cancers.

Download data

  • Downloaded 1,912 times
  • Download rankings, all-time:
    • Site-wide: 2,542 out of 65,454
    • In cancer biology: 59 out of 2,182
  • Year to date:
    • Site-wide: 16,975 out of 65,454
  • Since beginning of last month:
    • Site-wide: 37,128 out of 65,454

Altmetric data


Downloads over time

Distribution of downloads per paper, site-wide


Sign up for the Rxivist weekly newsletter! (Click here for more details.)


News