Decreased SARS-CoV-2 viral load following vaccination
By
Matan Levine-Tiefenbrun,
Idan Yelin,
Rachel Katz,
Esma Herzel,
Ziv Golan,
Licita Schreiber,
Tamar Wolf,
Varda Nadler,
Amir Ben-Tov,
Jacob Kuint,
Sivan Gazit,
Tal Patalon,
Gabriel Chodick,
Roy Kishony
Posted 08 Feb 2021
medRxiv DOI: 10.1101/2021.02.06.21251283
Beyond their substantial protection of individual vaccinees, it is hoped that the COVID-19 vaccines would reduce viral load in breakthrough infections thereby further suppress onward transmission. Here, analyzing positive SARS-CoV-2 test results following inoculation with the BNT162b2 mRNA vaccine, we find that the viral load is reduced 4-fold for infections occurring 12-28 days after the first dose of vaccine. These reduced viral loads hint to lower infectiousness, further contributing to vaccine impact on virus spread.
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