High-throughput SARS-CoV-2 and host genome sequencing from single nasopharyngeal swabs
John E Gorzynski,
Hannah N De Jong,
Chris R Hughes,
Norma F. Neff,
Massa J. Shoura,
Malaya K. Sahoo,
Kalyan C. Mallempati,
Jeffrey W. Christle,
Matthew T. Wheeler,
Benjamin A. Pinsky,
Manuel A Rivas,
Carlos D. Bustamante,
Euan A. Ashley,
Victoria N. Parikh
Posted 29 Jul 2020
medRxiv DOI: 10.1101/2020.07.27.20163147
Posted 29 Jul 2020
During COVID19 and other viral pandemics, rapid generation of host and pathogen genomic data is critical to tracking infection and informing therapies. There is an urgent need for efficient approaches to this data generation at scale. We have developed a scalable, high throughput approach to generate high fidelity low pass whole genome and HLA sequencing, viral genomes, and representation of human transcriptome from single nasopharyngeal swabs of COVID19 patients.
- Downloaded 1,888 times
- Download rankings, all-time:
- Site-wide: 8,090
- In genetic and genomic medicine: 30
- Year to date:
- Site-wide: 4,845
- Since beginning of last month:
- Site-wide: 8,084
Downloads over time
Distribution of downloads per paper, site-wide
- 27 Nov 2020: The website and API now include results pulled from medRxiv as well as bioRxiv.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!