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Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled

By Sam S. Oh, Joshua Galanter, Neeta Thakur, Maria Pino-Yanes, Nicolas E Barcelo, Marquitta J White, Danille M de Bruin, Ruth M Greenblatt, Kirsten Bibbins-Domingo, Alan HB Wu, Luisa N. Borrell, Chris Gunter, Neil R Powe, Esteban G. Burchard

Posted 16 Dec 2015
bioRxiv DOI: 10.1101/034538 (published DOI: 10.1371/journal.pmed.1001918)

Summary Points Health disparities persist across race/ethnicity for the majority of Healthy People 2010 health indicators. Most physicians and scientists are informed by research extrapolated from a largely homogenous population, usually White and male. A growing proportion of Americans are not fully benefiting from clinical and biomedical advances since racial and ethnic minorities make up nearly 40% of the U.S. population. Ignoring the racial/ethnic diversity of the U.S. population is a missed scientific opportunity to fully understand the factors that lead to disease or health. U.S. biomedical research and study populations must better reflect the country's changing demographics. Adequate representation of diverse populations in scientific research is imperative as a matter of social justice, economics, and science.

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