Psychiatric Genomics: An Update and an Agenda
Patrick F Sullivan,
Cynthia M. Bulik,
Ole A Andreassen,
Anders D. Borglum,
Howard J Edenberg,
Stephen V. Faraone,
Carol A Mathews,
Caroline M. Nievergelt,
Jordan W. Smoller,
Michael C O’Donovan,
for the Psychiatric Genomics Consortium
Posted 10 Mar 2017
bioRxiv DOI: 10.1101/115600 (published DOI: 10.1176/appi.ajp.2017.17030283)
Posted 10 Mar 2017
The Psychiatric Genomics Consortium (PGC) is the largest consortium in the history of psychiatry. In the past decade, this global effort has delivered a rapidly increasing flow of new knowledge about the fundamental basis of common psychiatric disorders, particularly given its dedication to rapid progress and open science. The PGC has recently commenced a program of research designed to deliver “actionable” findings - genomic results that (a) reveal the fundamental biology, (b) inform clinical practice, and (c) deliver new therapeutic targets. This is the central idea of the PGC: to convert the family history risk factor into biologically, clinically, and therapeutically meaningful insights. The emerging findings suggest that we are entering into a phase of accelerated translation of genetic discoveries to impact psychiatric practice within a precision medicine framework.
- Downloaded 3,297 times
- Download rankings, all-time:
- Site-wide: 1,824 out of 100,936
- In genetics: 129 out of 5,022
- Year to date:
- Site-wide: 36,251 out of 100,936
- Since beginning of last month:
- Site-wide: 52,968 out of 100,936
Downloads over time
Distribution of downloads per paper, site-wide
- 20 Oct 2020: Support for sorting preprints using Twitter activity has been removed, at least temporarily, until a new source of social media activity data becomes available.
- 18 Dec 2019: We're pleased to announce PanLingua, a new tool that enables you to search for machine-translated bioRxiv preprints using more than 100 different languages.
- 21 May 2019: PLOS Biology has published a community page about Rxivist.org and its design.
- 10 May 2019: The paper analyzing the Rxivist dataset has been published at eLife.
- 1 Mar 2019: We now have summary statistics about bioRxiv downloads and submissions.
- 8 Feb 2019: Data from Altmetric is now available on the Rxivist details page for every preprint. Look for the "donut" under the download metrics.
- 30 Jan 2019: preLights has featured the Rxivist preprint and written about our findings.
- 22 Jan 2019: Nature just published an article about Rxivist and our data.
- 13 Jan 2019: The Rxivist preprint is live!