Author: David D Ho

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Preprints

Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques

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Increased Resistance of SARS-CoV-2 Variant P.1 to Antibody Neutralization

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Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

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A Novel SARS-CoV-2 Variant of Concern, B.1.526, Identified in New York

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Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids

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Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains

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Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike

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Identification of Drugs Blocking SARS-CoV-2 Infection using Human Pluripotent Stem Cell-derived Colonic Organoids

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Real-time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles

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Densely sampled viral trajectories suggest longer duration of acute infection with B.1.1.7 variant relative to non-B.1.1.7 SARS-CoV-2

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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

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Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite

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SARS-CoV-2 Neutralizing Antibody Responses Are More Robust in Patients with Severe Disease

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A simplified cell-based assay to identify coronavirus 3CL protease inhibitors

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Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

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Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors

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Angiotensin converting enzyme 2 is a novel target of the γ-secretase complex

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Structural Basis for Accommodation of Emerging B.1.351 and B.1.1.7 Variants by Two Potent SARS-CoV-2 Neutralizing Antibodies

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Efficacy of a Broadly Neutralizing SARS-CoV-2 Ferritin Nanoparticle Vaccine in Nonhuman Primates

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Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class

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Virus-Like Particle Based-Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide

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