Author: Rita E. Chen

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Preprints

Structural and functional analysis of a potent sarbecovirus neutralizing antibody

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Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

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Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2

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Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals

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Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2.

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De novo design of picomolar SARS-CoV-2 miniprotein inhibitors

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SARS-CoV-2 infection in the lungs of human ACE2 transgenic mice causes severe inflammation, immune cell infiltration, and compromised respiratory function

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A single intranasal dose of chimpanzee adenovirus-vectored vaccine confers sterilizing immunity against SARS-CoV-2 infection

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Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis

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Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization

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Association between neutralizing antibodies to SARS-CoV-2 and commercial serological assays

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Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions and monocytes for optimal therapeutic protection

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Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations

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  • In synthetic biology: 612
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Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

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