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Author: Xu Zhang

Rankings

  • All-time downloads: 90,203 (rank: 2,395 )
  • Categories:
    • biochemistry: 870 (rank: 9,072 (tie) )
    • bioengineering: 531 (rank: 10,556 (tie) )
    • bioinformatics: 1,399 (rank: 13,805 (tie) )
    • cancer biology: 3,546 (rank: 1,774 )
    • cell biology: 5,139 (rank: 1,141 )
    • developmental biology: 3,516 (rank: 954 )
    • epidemiology: 536 (rank: 21,205 (tie) )
    • evolutionary biology: 1,358 (rank: 6,116 (tie) )
    • genomics: 2,669 (rank: 10,835 (tie) )
    • immunology: 485 (rank: 27,273 (tie) )
    • infectious diseases: 761 (rank: 37,930 (tie) )
    • intensive care and critical care medicine: 473 (rank: 2,530 (tie) )
    • microbiology: 48,961 (rank: 364 )
    • molecular biology: 1,345 (rank: 5,616 (tie) )
    • neuroscience: 9,268 (rank: 2,077 (tie) )
    • pathology: 226 (rank: 7,657 (tie) )
    • public and global health: 2,426 (rank: 2,413 (tie) )
    • synthetic biology: 587 (rank: 4,454 (tie) )
    • systems biology: 1,416 (rank: 3,875 (tie) )

Downloads per author, site-wide

Preprints

Isolation and Characterization of 2019-nCoV-like Coronavirus from Malayan Pangolins

microbiology more details view paper
  • Downloaded 17,741 times
  • Download rankings, all-time:
    • Site-wide: 617
    • In microbiology: 65
  • Year to date:
    • Site-wide: 5,735
  • Since beginning of last month:
    • Site-wide: 7,526

The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I

microbiology more details view paper
  • Downloaded 16,850 times
  • Download rankings, all-time:
    • Site-wide: 659
    • In microbiology: 68
  • Year to date:
    • Site-wide: 6,923
  • Since beginning of last month:
    • Site-wide: 12,113

Glycopeptide antibiotic teicoplanin inhibits cell entry of SARS-CoV-2 by suppressing the proteolytic activity of cathepsin L

microbiology more details view paper
  • Downloaded 8,214 times
  • Download rankings, all-time:
    • Site-wide: 1,636
    • In microbiology: 146
  • Year to date:
    • Site-wide: 19,464
  • Since beginning of last month:
    • Site-wide: 24,653

Variability in the analysis of a single neuroimaging dataset by many teams

neuroscience more details view paper
  • Downloaded 6,987 times
  • Download rankings, all-time:
    • Site-wide: 2,019
    • In neuroscience: 85
  • Year to date:
    • Site-wide: 49,383
  • Since beginning of last month:
    • Site-wide: 56,657

A versatile two-step CRISPR- and RMCE-based strategy for efficient genome engineering in Drosophila

developmental biology more details view paper
  • Downloaded 2,985 times
  • Download rankings, all-time:
    • Site-wide: 6,585
    • In developmental biology: 63
  • Year to date:
    • Site-wide: 155,828
  • Since beginning of last month:
    • Site-wide: 157,409

Quantitative analysis of SARS-CoV-2 RNA from wastewater solids in communities with low COVID-19 incidence and prevalence

public and global health more details view paper
  • Downloaded 2,545 times
  • Download rankings, all-time:
    • Site-wide: 8,335
    • In public and global health: 225
  • Year to date:
    • Site-wide: 21,555
  • Since beginning of last month:
    • Site-wide: 47,268

A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues

cell biology more details view paper
  • Downloaded 2,158 times
  • Download rankings, all-time:
    • Site-wide: 10,604
    • In cell biology: 605
  • Year to date:
    • Site-wide: 1,238
  • Since beginning of last month:
    • Site-wide: 1,134

SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation

microbiology more details view paper
  • Downloaded 2,068 times
  • Download rankings, all-time:
    • Site-wide: 11,337
    • In microbiology: 981
  • Year to date:
    • Site-wide: 632
  • Since beginning of last month:
    • Site-wide: 27,504

3D observation of large-scale subcellular dynamics in vivo at the millisecond scale

cell biology more details view paper
  • Downloaded 1,559 times
  • Download rankings, all-time:
    • Site-wide: 17,304
    • In cell biology: 463
  • Year to date:
    • Site-wide: 123,768
  • Since beginning of last month:
    • Site-wide: 130,459

Single-cell RNA-seq reveals endoimmune cells in zebrafish

cell biology more details view paper
  • Downloaded 1,185 times
  • Download rankings, all-time:
    • Site-wide: 26,431
    • In cell biology: 863
  • Year to date:
    • Site-wide: 108,374
  • Since beginning of last month:
    • Site-wide: 98,003

Imaging chromatin interactions at sub-kilobase resolution Via Tn5-FISH

cell biology more details view paper
  • Downloaded 1,114 times
  • Download rankings, all-time:
    • Site-wide: 29,055
    • In cell biology: 975
  • Year to date:
    • Site-wide: 109,807
  • Since beginning of last month:
    • Site-wide: 162,919

A ribosome assembly stress response regulates transcription to maintain proteome homeostasis

molecular biology more details view paper
  • Downloaded 1,036 times
  • Download rankings, all-time:
    • Site-wide: 32,425
    • In molecular biology: 811
  • Year to date:
    • Site-wide: 115,676
  • Since beginning of last month:
    • Site-wide: 132,528

RapidAIM: A culture- and metaproteomics-based Rapid Assay of Individual Microbiome responses to drugs

microbiology more details view paper
  • Downloaded 1,020 times
  • Download rankings, all-time:
    • Site-wide: 33,168
    • In microbiology: 1,797
  • Year to date:
    • Site-wide: 160,443
  • Since beginning of last month:
    • Site-wide: 137,011

Control of mammalian brain aging by the unfolded protein response (UPR)

neuroscience more details view paper
  • Downloaded 991 times
  • Download rankings, all-time:
    • Site-wide: 34,628
    • In neuroscience: 4,404
  • Year to date:
    • Site-wide: 54,684
  • Since beginning of last month:
    • Site-wide: 73,182

MyoD is a structure organizer of 3D genome architecture in muscle cells

genomics more details view paper
  • Downloaded 951 times
  • Download rankings, all-time:
    • Site-wide: 36,857
    • In genomics: 2,921
  • Year to date:
    • Site-wide: 58,304
  • Since beginning of last month:
    • Site-wide: 67,280

Pathogenicity, tissue tropism and potential vertical transmission of SARSr-CoV-2 in Malayan pangolins

microbiology more details view paper
  • Downloaded 895 times
  • Download rankings, all-time:
    • Site-wide: 40,271
    • In microbiology: 2,358
  • Year to date:
    • Site-wide: 78,480
  • Since beginning of last month:
    • Site-wide: 125,259

Genome wide sequencing provides evidence of adaptation to heterogeneous environments for the ancient relictual Circaeaster agrestis (Circaeasteraceae, Ranunculales)

evolutionary biology more details view paper
  • Downloaded 883 times
  • Download rankings, all-time:
    • Site-wide: 41,079
    • In evolutionary biology: 1,880
  • Year to date:
    • Site-wide: 44,827
  • Since beginning of last month:
    • Site-wide: 51,142

DNA 5-Hydroxymethylcytosines from Cell-free Circulating DNA as Diagnostic Biomarkers for Human Cancers

cancer biology more details view paper
  • Downloaded 880 times
  • Download rankings, all-time:
    • Site-wide: 41,294
    • In cancer biology: 1,021
  • Year to date:
    • Site-wide: 161,908
  • Since beginning of last month:
    • Site-wide: 184,311

Performance of a point of care test for detecting IgM and IgG antibodies against SARS-CoV-2 and seroprevalence in blood donors and health care workers in Panama

infectious diseases more details view paper
  • Downloaded 801 times
  • Download rankings, all-time:
    • Site-wide: 47,489
    • In infectious diseases: 3,420
  • Year to date:
    • Site-wide: 71,573
  • Since beginning of last month:
    • Site-wide: 61,109

Integrated proteogenomic analysis of metastatic thoracic tumors identifies APOBEC mutagenesis and copy number alterations as drivers of proteogenomic tumor evolution and heterogeneity

cancer biology more details view paper
  • Downloaded 754 times
  • Download rankings, all-time:
    • Site-wide: 51,845
    • In cancer biology: 1,339
  • Year to date:
    • Site-wide: 149,025
  • Since beginning of last month:
    • Site-wide: 130,267

MetaLab 2.0 enables accurate post-translational modifications profiling in metaproteomics

bioinformatics more details view paper
  • Downloaded 751 times
  • Download rankings, all-time:
    • Site-wide: 52,085
    • In bioinformatics: 5,269
  • Year to date:
    • Site-wide: 59,328
  • Since beginning of last month:
    • Site-wide: 43,891

Real-time environmental monitoring of contaminants using living electronic sensors

synthetic biology more details view paper
  • Downloaded 732 times
  • Download rankings, all-time:
    • Site-wide: 54,008
    • In synthetic biology: 780
  • Year to date:
    • Site-wide: 23,587
  • Since beginning of last month:
    • Site-wide: 14,321

Growth phase-dependent responses of an in vitro gut microbiome to metformin

microbiology more details view paper
  • Downloaded 723 times
  • Download rankings, all-time:
    • Site-wide: 55,043
    • In microbiology: 3,278
  • Year to date:
    • Site-wide: 68,598
  • Since beginning of last month:
    • Site-wide: 73,490

Multiple expression assessments of ACE2 and TMPRSS2 SARS-CoV-2 entry molecules in the urinary tract and their associations with clinical manifestations of COVID-19

biochemistry more details view paper
  • Downloaded 712 times
  • Download rankings, all-time:
    • Site-wide: 56,101
    • In biochemistry: 1,381
  • Year to date:
    • Site-wide: 114,555
  • Since beginning of last month:
    • Site-wide: 91,926

Non-invasive Amelioration of Essential Tremor via Phase-Locked Disruption of its Temporal Coherence

neuroscience more details view paper
  • Downloaded 681 times
  • Download rankings, all-time:
    • Site-wide: 59,902
    • In neuroscience: 8,521
  • Year to date:
    • Site-wide: 72,424
  • Since beginning of last month:
    • Site-wide: 124,967

5-Hydroxymethylcytosines from Circulating Cell-free DNA as Diagnostic and Prognostic Markers for Hepatocellular Carcinoma

cancer biology more details view paper
  • Downloaded 633 times
  • Download rankings, all-time:
    • Site-wide: 65,892
    • In cancer biology: 1,754
  • Year to date:
    • Site-wide: 161,819
  • Since beginning of last month:
    • Site-wide: 131,919

A Chemoenzymatic Method for Glycoproteomic N-glycan Type Quantitation

systems biology more details view paper
  • Downloaded 624 times
  • Download rankings, all-time:
    • Site-wide: 67,176
    • In systems biology: 1,387
  • Year to date:
    • Site-wide: 97,264
  • Since beginning of last month:
    • Site-wide: 67,056

Cholecystokinin release triggered by presynaptic NMDA receptors produces LTP and sound-sound associative memory formation

neuroscience more details view paper
  • Downloaded 609 times
  • Download rankings, all-time:
    • Site-wide: 69,220
    • In neuroscience: 9,330
  • Year to date:
    • Site-wide: 132,252
  • Since beginning of last month:
    • Site-wide: 108,322

A general model to explain repeated turnovers of sex determination in the Salicaceae

genomics more details view paper
  • Downloaded 597 times
  • Download rankings, all-time:
    • Site-wide: 71,122
    • In genomics: 4,583
  • Year to date:
    • Site-wide: 183,103
  • Since beginning of last month:
    • Site-wide: 173,636

Modeling SARS-CoV-2 infection in vitro with a human intestine-on-chip device

bioengineering more details view paper
  • Downloaded 566 times
  • Download rankings, all-time:
    • Site-wide: 76,018
    • In bioengineering: 1,429
  • Year to date:
    • Site-wide: 88,798
  • Since beginning of last month:
    • Site-wide: 91,966

Systematic transcriptomics reveals a biphasic mode of sarcomere morphogenesis in flight muscles regulated by Spalt

developmental biology more details view paper
  • Downloaded 564 times
  • Download rankings, all-time:
    • Site-wide: 76,290
    • In developmental biology: 1,773
  • Year to date:
    • Site-wide: 123,431
  • Since beginning of last month:
    • Site-wide: 109,869

Catching a resurgence: Increase in SARS-CoV-2 viral RNA identified in wastewater 48 hours before COVID-19 clinical tests and 96 hours before hospitalizations

epidemiology more details view paper
  • Downloaded 560 times
  • Download rankings, all-time:
    • Site-wide: 77,044
    • In epidemiology: 3,303
  • Year to date:
    • Site-wide: 117,309
  • Since beginning of last month:
    • Site-wide: 180,910

Metaproteomic responses of in vitro gut microbiomes to resistant starches: the role of resistant starch type and inter-individual variations

microbiology more details view paper
  • Downloaded 560 times
  • Download rankings, all-time:
    • Site-wide: 77,006
    • In microbiology: 4,607
  • Year to date:
    • Site-wide: 142,870
  • Since beginning of last month:
    • Site-wide: 146,987

pepFunk, a tool for peptide-centric functional analysis in metaproteomic human gut microbiome studies

bioinformatics more details view paper
  • Downloaded 551 times
  • Download rankings, all-time:
    • Site-wide: 78,530
    • In bioinformatics: 6,911
  • Year to date:
    • Site-wide: 125,543
  • Since beginning of last month:
    • Site-wide: 140,143

Quantitative mass spectrometry to interrogate proteomic heterogeneity in metastatic lung adenocarcinoma and validate a novel somatic mutation CDK12-G879V

cancer biology more details view paper
  • Downloaded 543 times
  • Download rankings, all-time:
    • Site-wide: 79,947
    • In cancer biology: 2,144
  • Year to date:
    • Site-wide: 149,078
  • Since beginning of last month:
    • Site-wide: 165,662

Global proteome and phosphoproteome alterations in third generation EGFR TKI resistance reveal drug targets to circumvent resistance

cancer biology more details view paper
  • Downloaded 511 times
  • Download rankings, all-time:
    • Site-wide: 85,883
    • In cancer biology: 2,501
  • Year to date:
    • Site-wide: 84,510
  • Since beginning of last month:
    • Site-wide: 91,642

Different Incidence of Acute Kidney Injury In Adult Patients Receiving Different types Extracorporeal Membrane Oxygenation: A Meta-Analysis

intensive care and critical care medicine more details view paper
  • Downloaded 497 times
  • Download rankings, all-time:
    • Site-wide: 88,797
    • In intensive care and critical care medicine: 216
  • Year to date:
    • Site-wide: 114,328
  • Since beginning of last month:
    • Site-wide: 139,403

In Vitro Potent Activity of ε-poly-L-lysine against Candida albicans and the Underlying Mechanisms

microbiology more details view paper
  • Downloaded 482 times
  • Download rankings, all-time:
    • Site-wide: 91,861
    • In microbiology: 5,824
  • Year to date:
    • Site-wide: 106,906
  • Since beginning of last month:
    • Site-wide: 89,141

De novo assembly of trachidermus fasciatus genome by nanopore sequencing

genomics more details view paper
  • Downloaded 473 times
  • Download rankings, all-time:
    • Site-wide: 93,739
    • In genomics: 5,674
  • Year to date:
    • Site-wide: 121,547
  • Since beginning of last month:
    • Site-wide: 78,366

Deep characterization of the protein lysine acetylation in human gut microbiome and its alterations in patients with Crohn's disease

systems biology more details view paper
  • Downloaded 438 times
  • Download rankings, all-time:
    • Site-wide: 101,743
    • In systems biology: 2,076
  • Year to date:
    • Site-wide: 157,377
  • Since beginning of last month:
    • Site-wide: 113,181

The draft genome of the endangered, relictual plant Kingdonia uniflora (Circaeasteraceae, Ranunculales) reveals potential mechanisms and perils of evolutionary specialization

genomics more details view paper
  • Downloaded 430 times
  • Download rankings, all-time:
    • Site-wide: 103,525
    • In genomics: 5,963
  • Year to date:
    • Site-wide: 133,636
  • Since beginning of last month:
    • Site-wide: 111,264

Proteogenomic analysis unveils the HLA Class I presented immunopeptidome in melanoma and EGFR mutant lung adenocarcinoma

immunology more details view paper
  • Downloaded 421 times
  • Download rankings, all-time:
    • Site-wide: 105,729
    • In immunology: 3,168
  • Year to date:
    • Site-wide: 92,934
  • Since beginning of last month:
    • Site-wide: 59,305

An in vitro model maintaining taxon-specific functional activities of the gut microbiome

microbiology more details view paper
  • Downloaded 419 times
  • Download rankings, all-time:
    • Site-wide: 106,342
    • In microbiology: 6,669
  • Year to date:
    • Site-wide: 180,770
  • Since beginning of last month:
    • Site-wide: 181,674

Genomic characterization of a lumpy skin disease virus isolated in southeast China

genomics more details view paper
  • Downloaded 413 times
  • Download rankings, all-time:
    • Site-wide: 107,616
    • In genomics: 6,675
  • Year to date:
    • Site-wide: 38,234
  • Since beginning of last month:
    • Site-wide: 52,024

Studying the dynamics of the gut microbiota using metabolically stable isotopic labeling and metaproteomics.

microbiology more details view paper
  • Downloaded 378 times
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    • Site-wide: 116,704
    • In microbiology: 7,433
  • Year to date:
    • Site-wide: 183,348
  • Since beginning of last month:
    • Site-wide: 153,995

Comprehensive assessment of functional effects of commonly used sweeteners on ex vivo human gut microbiome

microbiology more details view paper
  • Downloaded 366 times
  • Download rankings, all-time:
    • Site-wide: 119,961
    • In microbiology: 9,889
  • Year to date:
    • Site-wide: 8,288
  • Since beginning of last month:
    • Site-wide: 56,030

Identification of a new orthonairovirus associated with human febrile illness in China

microbiology more details view paper
  • Downloaded 361 times
  • Download rankings, all-time:
    • Site-wide: 121,268
    • In microbiology: 8,282
  • Year to date:
    • Site-wide: 101,705
  • Since beginning of last month:
    • Site-wide: 127,282

A novel small molecule that induces cytotoxicity in lung cancer cells inhibits disulfide reductases GSR and TXNRD1

cancer biology more details view paper
  • Downloaded 356 times
  • Download rankings, all-time:
    • Site-wide: 122,657
    • In cancer biology: 3,571
  • Year to date:
    • Site-wide: 61,046
  • Since beginning of last month:
    • Site-wide: 93,635

CHRAC/ACF Contribute to the Repressive Ground State of Chromatin

molecular biology more details view paper
  • Downloaded 344 times
  • Download rankings, all-time:
    • Site-wide: 126,167
    • In molecular biology: 3,456
  • Year to date:
    • Site-wide: 179,574
  • Since beginning of last month:
    • Site-wide: 178,291

Insights into the drivers of radiating diversification in biodiversity hotspots using Saussurea (Asteraceae) as a case

evolutionary biology more details view paper
  • Downloaded 338 times
  • Download rankings, all-time:
    • Site-wide: 127,689
    • In evolutionary biology: 6,174
  • Year to date:
    • Site-wide: 75,862
  • Since beginning of last month:
    • Site-wide: 61,506

Plastome phylogenomic study of Gentianeae (Gentianaceae): widespread gene tree discordance and its association with evolutionary rate heterogeneity of plastid genes

evolutionary biology more details view paper
  • Downloaded 298 times
  • Download rankings, all-time:
    • Site-wide: 139,487
    • In evolutionary biology: 6,327
  • Year to date:
    • Site-wide: 147,480
  • Since beginning of last month:
    • Site-wide: 126,917

NAD metabolism modulates mitochondrial function and inflammation and prevents progression of diabetic kidney disease

pathology more details view paper
  • Downloaded 296 times
  • Download rankings, all-time:
    • Site-wide: 140,095
    • In pathology: 857
  • Year to date:
    • Site-wide: 36,867
  • Since beginning of last month:
    • Site-wide: 51,663

Revealing Protein-Level Functional Redundancy in the Human Gut Microbiome using Ultra-deep Metaproteomics

systems biology more details view paper
  • Downloaded 292 times
  • Download rankings, all-time:
    • Site-wide: 141,428
    • In systems biology: 2,945
  • Year to date:
    • Site-wide: 77,433
  • Since beginning of last month:
    • Site-wide: 57,303

Flotillin-2 regulates EGFR activation, degradation, and cancer growth

cancer biology more details view paper
  • Downloaded 288 times
  • Download rankings, all-time:
    • Site-wide: 142,564
    • In cancer biology: None
  • Year to date:
    • Site-wide: 11,869
  • Since beginning of last month:
    • Site-wide: 34,910

Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection

microbiology more details view paper
  • Downloaded 266 times
  • Download rankings, all-time:
    • Site-wide: 149,242
    • In microbiology: None
  • Year to date:
    • Site-wide: 13,509
  • Since beginning of last month:
    • Site-wide: 17,822

MetaProClust-MS1: A tool for clustering metaproteomes using rapid MS1 profiling

bioinformatics more details view paper
  • Downloaded 224 times
  • Download rankings, all-time:
    • Site-wide: 160,927
    • In bioinformatics: 11,905
  • Year to date:
    • Site-wide: 95,794
  • Since beginning of last month:
    • Site-wide: 96,904

Parvalbumin interneurons in the nucleus accumbens regulate impairment of risk avoidance in DISC1 transgenic mice

neuroscience more details view paper
  • Downloaded 218 times
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    • Site-wide: 162,706
    • In neuroscience: 22,713
  • Year to date:
    • Site-wide: 173,554
  • Since beginning of last month:
    • Site-wide: 172,619

Exploring the microbiome-wide lysine acetylation, succinylation and propionylation in human gut microbiota

microbiology more details view paper
  • Downloaded 210 times
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    • Site-wide: 164,825
    • In microbiology: 11,530
  • Year to date:
    • Site-wide: 164,160
  • Since beginning of last month:
    • Site-wide: 142,916

Understanding of the 2-oxoglutarate dehydrogenase and 2-oxoadipate dehydrogenase assembly with the E2o core relevant to a hybrid complex formation

biochemistry more details view paper
  • Downloaded 208 times
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    • Site-wide: 165,340
    • In biochemistry: 4,864
  • Year to date:
    • Site-wide: 126,313
  • Since beginning of last month:
    • Site-wide: 104,443

Elevated colonic microbiota-associated paucimannosidic and truncated N-glycans in pediatric ulcerative colitis

systems biology more details view paper
  • Downloaded 177 times
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    • Site-wide: 172,893
    • In systems biology: 3,279
  • Year to date:
    • Site-wide: 174,611
  • Since beginning of last month:
    • Site-wide: 171,456

Evaluating live microbiota biobanking using an ex vivo microbiome assay and metaproteomics

microbiology more details view paper
  • Downloaded 168 times
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    • Site-wide: 174,880
    • In microbiology: 12,791
  • Year to date:
    • Site-wide: 74,370
  • Since beginning of last month:
    • Site-wide: 106,081

Examining the effects of an anti-Salmonella bacteriophage preparation, BAFASAL, on ex vivo human gut microbiome composition and function using a multi-omics approach

microbiology more details view paper
  • Downloaded 161 times
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    • Site-wide: 176,403
    • In microbiology: 12,499
  • Year to date:
    • Site-wide: 168,993
  • Since beginning of last month:
    • Site-wide: 143,684

Tropomyosin in mugwort cross-reacts to house dust mite, eliciting non-Th2 response in allergic rhinitis patients sensitized to house dust mite

immunology more details view paper
  • Downloaded 108 times
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    • Site-wide: 185,217
    • In immunology: 5,442
  • Year to date:
    • Site-wide: 186,945
  • Since beginning of last month:
    • Site-wide: 172,793

Genomic analyses provide new insights into the evolutionary history and reproduction of the Paleogene relictual Kingdonia (Circaeasteraceae, Ranunculales)

genomics more details view paper
  • Downloaded 39 times
  • Download rankings, all-time:
    • Site-wide: 191,016
    • In genomics: None
  • Year to date:
    • Site-wide: 108,670
  • Since beginning of last month:
    • Site-wide: 39,192

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