Author: Ian J Deary

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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The genetic architecture of the human cerebral cortex

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Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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Genetic analysis identifies molecular systems and biological pathways associated with household income

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Genome-wide association study identifies 48 common genetic variants associated with handedness

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Molecular genetic contributions to self-rated health

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Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117).

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Genetic “General Intelligence,” Objectively Determined and Measured

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GWAS on family history of Alzheimer's disease

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Genetic Prediction of Male Pattern Baldness

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Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

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Age differences in brain white matter microstructure in UK Biobank (N = 3,513)

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New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

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Mapping Cortical Brain Asymmetry in 17,141 Healthy Individuals Worldwide via the ENIGMA Consortium

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Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

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OSCA: a tool for omic-data-based complex trait analysis

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Subcortical volume and white matter integrity abnormalities in major depressive disorder: findings from UK Biobank imaging data

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Identification of 55,000 Replicated DNA Methylation QTL

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An epigenome-wide association study of educational attainment (n = 10,767)

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Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

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GWAS of epigenetic ageing rates in blood reveals a critical role for TERT

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Genome wide analysis of gene dosage in 24,092 individuals shows that 10,000 genes modulate cognitive ability

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Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

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Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

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Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

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Factors associated with sharing email information and mental health survey participation in large population cohorts

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Partial derivatives meta-analysis: pooled analyses when individual participant data cannot be shared

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Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

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Genetic contributions to self-reported tiredness

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Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data

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DNA methylation age acceleration and risk factors for Alzheimer's disease

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Pleiotropy between neuroticism and physical and mental health: findings from 108 038 men and women in UK Biobank

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Epigenetic clocks predict prevalence and incidence of leading causes of death and disease burden

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Age-related clonal haemopoiesis is associated with increased epigenetic age

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Accelerated Epigenetic Ageing in Major Depressive Disorder

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Linked mutations at adjacent nucleotides have shaped human population differentiation and protein evolution

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An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort 1936.

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The effect of network thresholding and weighting on structural brain networks in the UK Biobank

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Polygenic predictors of age-related decline in cognitive ability

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Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions

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Integrative omics approach to identify the molecular architecture of inflammatory protein levels in healthy older adults

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Genetic contributions to trail making test performance in UK Biobank

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Brain Structural Differences Between 73- And 92-Year Olds Matched For Childhood Intelligence, Social Background, And Intracranial Volume

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Birth weight associations with psychiatric and physical health, cognitive function, and DNA methylation differences in an adult population

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Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

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Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

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Genetic correlations between pain phenotypes and depression and neuroticism

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Genetic and epigenetic architectures of neurological protein biomarkers in the Lothian Birth Cohort 1936

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Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

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Genetic risk for neurodegenerative disorders, and its overlap with cognitive ability and physical function

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Age-related changes of Peak width Skeletonized Mean Diffusivity (PSMD) across the adult life span: a multi-cohort study

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Genetic contributions to health literacy

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Enhanced prediction of cognitive function using aging-sensitive networks within the human structural connectome

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Rare Genetic Variants Underlie Outlying levels of DNA Methylation and Gene-Expression

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Association of Facial Aging with DNA Methylation and Epigenetic Age Predictions

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Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell counts and epigenetic ageing

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Epigenetic signatures of starting and stopping smoking

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Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936

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Neurology-related protein biomarkers are associated with general fluid cognitive ability and brain volume in older age

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Plasma lipid and liporotein biomarkers in LBC1936: Do they predict general cognitive ability and brain structure?

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