Author: Wei Liu

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Preprints

Serology characteristics of SARS-CoV-2 infection since the exposure and post symptoms onset

• Downloaded 32,832 times
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  • Site-wide: 171
  • In infectious diseases: 67
• Year to date:
  • Site-wide: 4,948
• Since beginning of last month:
  • Site-wide: 4,512

Proteomic and Metabolomic Characterization of COVID-19 Patient Sera

• Downloaded 12,636 times
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  • Site-wide: 502
  • In infectious diseases: 168
• Year to date:
  • Site-wide: 17,018
• Since beginning of last month:
  • Site-wide: 8,251

Calcium channel blocker amlodipine besylate is associated with reduced case fatality rate of COVID-19 patients with hypertension

• Downloaded 5,785 times
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  • Site-wide: 1,428
  • In pathology: 11
• Year to date:
  • Site-wide: 4,142
• Since beginning of last month:
  • Site-wide: 3,285

The impact of temperature and absolute humidity on the coronavirus disease 2019 (COVID-19) outbreak - evidence from China

• Downloaded 5,693 times
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  • Site-wide: 1,468
  • In occupational and environmental health: 9
• Year to date:
  • Site-wide: 4,073
• Since beginning of last month:
  • Site-wide: 10,778

Multi-organ Proteomic Landscape of COVID-19 Autopsies

• Downloaded 1,754 times
• Download rankings, all-time:
  • Site-wide: 7,987
  • In infectious diseases: 967
• Year to date:
  • Site-wide: 486
• Since beginning of last month:
  • Site-wide: 3,456

Estimating prevalence for limb-girdle muscular dystrophy based on public sequencing databases

• Downloaded 1,661 times
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  • Site-wide: 8,732
  • In epidemiology: 624
• Year to date:
  • Site-wide: 47,892
• Since beginning of last month:
  • Site-wide: 19,587

Parallel loss of symbiosis genes in relatives of nitrogen-fixing non-legume Parasponia

• Downloaded 1,453 times
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  • Site-wide: 10,629
  • In plant biology: 124
• Year to date:
  • Site-wide: 54,133
• Since beginning of last month:
  • Site-wide: 57,184

Neutralizing and binding antibody kinetics of COVID-19 patients during hospital and convalescent phases

• Downloaded 1,435 times
• Download rankings, all-time:
  • Site-wide: 10,821
  • In infectious diseases: 1,138
• Year to date:
  • Site-wide: 8,676
• Since beginning of last month:
  • Site-wide: 4,330

Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer's disease

• Downloaded 1,293 times
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  • Site-wide: 12,683
  • In genetics: 652
• Year to date:
  • Site-wide: 109,575
• Since beginning of last month:
  • Site-wide: 100,645

Ccube: A fast and robust method for estimating cancer cell fractions

• Downloaded 1,280 times
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  • Site-wide: 12,868
  • In bioinformatics: 1,613
• Year to date:
  • Site-wide: 10,917
• Since beginning of last month:
  • Site-wide: 25,608

Protein Classifier for Thyroid Nodules Learned from Rapidly Acquired Proteotypes

• Downloaded 1,159 times
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  • Site-wide: 14,935
  • In oncology: 14
• Year to date:
  • Site-wide: 3,691
• Since beginning of last month:
  • Site-wide: 6,512

Cryo-EM structure of the receptor-activated TRPC5 ion channel at 2.9 angstrom resolution

• Downloaded 1,105 times
• Download rankings, all-time:
  • Site-wide: 16,079
  • In biophysics: 405
• Year to date:
  • Site-wide: 69,726
• Since beginning of last month:
  • Site-wide: 61,269

Structural and functional MRI from a cross-sectional Southwest University Adult lifespan Dataset (SALD)

• Downloaded 1,101 times
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  • Site-wide: 16,186
  • In neuroscience: 2,041
• Year to date:
  • Site-wide: 42,015
• Since beginning of last month:
  • Site-wide: 21,219

Proteomics Uncovers Immunosuppression in COVID-19 Patients with Long Disease Course

• Downloaded 1,074 times
• Download rankings, all-time:
  • Site-wide: 16,802
  • In respiratory medicine: 54
• Year to date:
  • Site-wide: 8,648
• Since beginning of last month:
  • Site-wide: 15,437

Non-specific Primers Reveal False-negative Risk in Detection of COVID-19 Infections

• Downloaded 1,062 times
• Download rankings, all-time:
  • Site-wide: 17,084
  • In public and global health: 281
• Year to date:
  • Site-wide: 25,996
• Since beginning of last month:
  • Site-wide: 2,497

Leveraging functional annotation to identify genes associated with complex diseases

• Downloaded 932 times
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  • Site-wide: 20,688
  • In genetics: 1,033
• Year to date:
  • Site-wide: 67,767
• Since beginning of last month:
  • Site-wide: 57,777

Single-cell regulatory landscape and disease vulnerability map of adult Macaque cortex

• Downloaded 907 times
• Download rankings, all-time:
  • Site-wide: 21,509
  • In neuroscience: 2,848
• Year to date:
  • Site-wide: 5,981
• Since beginning of last month:
  • Site-wide: 12,504

Structure determination from lipidic cubic phase embedded microcrystals by MicroED

• Downloaded 900 times
• Download rankings, all-time:
  • Site-wide: 21,730
  • In biochemistry: 483
• Year to date:
  • Site-wide: 107,308
• Since beginning of last month:
  • Site-wide: 32,329

DPHL: A pan-human protein mass spectrometry library for robust biomarker discovery using Data-Independent Acquisition and Parallel Reaction Monitoring

• Downloaded 767 times
• Download rankings, all-time:
  • Site-wide: 27,233
  • In bioinformatics: 3,224
• Year to date:
  • Site-wide: 37,090
• Since beginning of last month:
  • Site-wide: 52,227

Application of high-resolution landmark-free morphometrics to a mouse model of Down Syndrome reveals a tightly localised cranial phenotype

• Downloaded 743 times
• Download rankings, all-time:
  • Site-wide: 28,468
  • In genetics: 1,436
• Year to date:
  • Site-wide: 13,364
• Since beginning of last month:
  • Site-wide: 30,881

A New Method for Primary Culture of Mouse Dorsal Root Ganglion Neurons

• Downloaded 555 times
• Download rankings, all-time:
  • Site-wide: 41,727
  • In neuroscience: 6,108
• Year to date:
  • Site-wide: 22,329
• Since beginning of last month:
  • Site-wide: 38,308

Decoys provide a scalable platform for the genetic analysis of plant E3 ubiquitin ligases that regulate circadian clock function

• Downloaded 521 times
• Download rankings, all-time:
  • Site-wide: 45,019
  • In plant biology: 1,059
• Year to date:
  • Site-wide: 97,810
• Since beginning of last month:
  • Site-wide: 56,574

Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs and mRNAs in live bacterial cells

• Downloaded 507 times
• Download rankings, all-time:
  • Site-wide: 46,500
  • In biophysics: 1,582
• Year to date:
  • Site-wide: 72,448
• Since beginning of last month:
  • Site-wide: 82,911

BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes

• Downloaded 504 times
• Download rankings, all-time:
  • Site-wide: 46,877
  • In cancer biology: 1,301
• Year to date:
  • Site-wide: 76,147
• Since beginning of last month:
  • Site-wide: 102,802

GIGANTEA recruits deubiquitylases, UBP12 and UBP13, to regulate accumulation of the ZTL photoreceptor complex

• Downloaded 498 times
• Download rankings, all-time:
  • Site-wide: 47,501
  • In plant biology: 1,131
• Year to date:
  • Site-wide: 69,537
• Since beginning of last month:
  • Site-wide: 93,579

Hippocampal-medial prefrontal event segmentation and integration contribute to episodic memory formation

• Downloaded 494 times
• Download rankings, all-time:
  • Site-wide: 48,000
  • In neuroscience: 7,164
• Year to date:
  • Site-wide: 7,166
• Since beginning of last month:
  • Site-wide: 10,815

A Registration and Deep Learning Approach to Automated Landmark Detection for Geometric Morphometrics

• Downloaded 451 times
• Download rankings, all-time:
  • Site-wide: 53,110
  • In evolutionary biology: 3,009
• Year to date:
  • Site-wide: 63,848
• Since beginning of last month:
  • Site-wide: 28,345

An effective, safe and cost-effective cell-based chimeric vaccine against SARS-CoV2

• Downloaded 447 times
• Download rankings, all-time:
  • Site-wide: 53,692
  • In immunology: 1,420
• Year to date:
  • Site-wide: 39,884
• Since beginning of last month:
  • Site-wide: 29,545

Common neural and transcriptional correlates of inhibitory control underlie emotion regulation and memory control

• Downloaded 429 times
• Download rankings, all-time:
  • Site-wide: 56,008
  • In neuroscience: 8,536
• Year to date:
  • Site-wide: 48,350
• Since beginning of last month:
  • Site-wide: 54,736

Two-step binding kinetics of tRNAGly by the glyQS T-box riboswitch and its regulation by T-box structural elements

• Downloaded 404 times
• Download rankings, all-time:
  • Site-wide: 59,544
  • In biophysics: 2,148
• Year to date:
  • Site-wide: 94,092
• Since beginning of last month:
  • Site-wide: 114,430

Regulation of olfactory-based sex behaviors in the silkworm by genes in the sex-determination cascade

• Downloaded 397 times
• Download rankings, all-time:
  • Site-wide: 60,579
  • In genetics: 2,896
• Year to date:
  • Site-wide: 59,940
• Since beginning of last month:
  • Site-wide: 26,923

Type-2 CD8+ T lymphocytes responsive to PGD2 and LTE4 in severe eosinophilic asthma

• Downloaded 373 times
• Download rankings, all-time:
  • Site-wide: 64,429
  • In immunology: 1,706
• Year to date:
  • Site-wide: 75,702
• Since beginning of last month:
  • Site-wide: 82,627

A Decoy Library Uncovers U-box E3 Ubiquitin Ligases that Regulate Flowering Time in Arabidopsis

• Downloaded 372 times
• Download rankings, all-time:
  • Site-wide: 64,589
  • In plant biology: 1,679
• Year to date:
  • Site-wide: 62,410
• Since beginning of last month:
  • Site-wide: 104,791

hTFtarget: a comprehensive database for regulations of human transcription factors and their targets

• Downloaded 372 times
• Download rankings, all-time:
  • Site-wide: 64,565
  • In bioinformatics: 6,334
• Year to date:
  • Site-wide: 33,593
• Since beginning of last month:
  • Site-wide: 95,934

Probing the neural dynamics of mnemonic representations after the initial consolidation

• Downloaded 372 times
• Download rankings, all-time:
  • Site-wide: 64,570
  • In neuroscience: 9,955
• Year to date:
  • Site-wide: 73,360
• Since beginning of last month:
  • Site-wide: 52,161

Specific Eph Receptor-Cytoplasmic Effector Signaling Mediated by SAM-SAM Domain Interactions

• Downloaded 318 times
• Download rankings, all-time:
  • Site-wide: 73,792
  • In biophysics: 2,776
• Year to date:
  • Site-wide: 103,302
• Since beginning of last month:
  • Site-wide: 120,879

Transmission dynamics and control measures of COVID-19 outbreak in China: a modelling study

• Downloaded 291 times
• Download rankings, all-time:
  • Site-wide: 78,966
  • In infectious diseases: 2,926
• Year to date:
  • Site-wide: 71,103
• Since beginning of last month:
  • Site-wide: 76,801

Variation of the vaginal microbiome during and after pregnancy in Chinese women

• Downloaded 286 times
• Download rankings, all-time:
  • Site-wide: 79,902
  • In genetic and genomic medicine: 245
• Year to date:
  • Site-wide: 18,338
• Since beginning of last month:
  • Site-wide: 22,493

A novel antiviral lncRNA EDAL shields a T309 O-GlcNAcylation site to promote EZH2 degradation

• Downloaded 278 times
• Download rankings, all-time:
  • Site-wide: 81,573
  • In microbiology: 5,752
• Year to date:
  • Site-wide: 85,529
• Since beginning of last month:
  • Site-wide: 72,185

A Cyclic Phosphoramidate Prodrug of 2’-deoxy-2’-fluoro-2’-C-methylguanosine for the Treatment of Dengue Infection

• Downloaded 257 times
• Download rankings, all-time:
  • Site-wide: 86,030
  • In microbiology: 6,185
• Year to date:
  • Site-wide: 28,972
• Since beginning of last month:
  • Site-wide: 34,492

Facial shape and allometry quantitative trait locus intervals in the Diversity Outbred mouse are enriched for known skeletal and facial development genes

• Downloaded 250 times
• Download rankings, all-time:
  • Site-wide: 87,346
  • In genetics: 4,037
• Year to date:
  • Site-wide: 60,393
• Since beginning of last month:
  • Site-wide: 95,759

NudCL2 is an Hsp90 cochaperone to regulate sister chromatid cohesion by stabilizing cohesin subunits

• Downloaded 249 times
• Download rankings, all-time:
  • Site-wide: 87,527
  • In cell biology: 4,080
• Year to date:
  • Site-wide: 109,368
• Since beginning of last month:
  • Site-wide: 114,101

The dynamic transition between neural states is associated with the flexible use of memory

• Downloaded 246 times
• Download rankings, all-time:
  • Site-wide: 88,309
  • In neuroscience: 13,895
• Year to date:
  • Site-wide: 21,923
• Since beginning of last month:
  • Site-wide: 17,360

Dynamic Analysis on Simultaneous iEEG-MEG Data via Hidden Markov Model

• Downloaded 211 times
• Download rankings, all-time:
  • Site-wide: 95,651
  • In neurology: 269
• Year to date:
  • Site-wide: 19,970
• Since beginning of last month:
  • Site-wide: 30,939

Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy

• Downloaded 202 times
• Download rankings, all-time:
  • Site-wide: 97,588
  • In genomics: 5,856
• Year to date:
  • Site-wide: 62,579
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  • Site-wide: 83,045

Emodin Attenuates Renal Interstitial Fibrosis via Regulation of TIMP1/MM9 Pathway in Rats

• Downloaded 195 times
• Download rankings, all-time:
  • Site-wide: 99,054
  • In molecular biology: 2,967
• Year to date:
  • Site-wide: 74,976
• Since beginning of last month:
  • Site-wide: 119,322

Real-time monitoring epidemic trends and key mutations in SARS-CoV-2 evolution by an automated tool

• Downloaded 184 times
• Download rankings, all-time:
  • Site-wide: 101,463
  • In genomics: 5,981
• Year to date:
  • Site-wide: 5,620
• Since beginning of last month:
  • Site-wide: 4,057

Evaluation of Ultrafast Wave-CAIPI 3D FLAIR in the Visualization and Volumetric Estimation of Cerebral White Matter Lesions

• Downloaded 70 times
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  • Site-wide: 121,354
  • In radiology and imaging: 245
• Year to date:
  • Site-wide: 4,434
• Since beginning of last month:
  • Site-wide: None

Unique intramolecular oxidative rearrangement N-nitrosation mechanism of non-heam iron-containing enzyme SznF

• Downloaded 59 times
• Download rankings, all-time:
  • Site-wide: 122,566
  • In biochemistry: 3,712
• Year to date:
  • Site-wide: 18,045
• Since beginning of last month:
  • Site-wide: 19,297