Author: Michael C O’Donovan

Downloads per author, site-wide

Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

• Downloaded 9,086 times
• Download rankings, all-time:
  • Site-wide: 284 out of 89,274
  • In genetics: 21 out of 4,618
• Year to date:
  • Site-wide: 14,165 out of 89,274
• Since beginning of last month:
  • Site-wide: 14,356 out of 89,274

Contrasting regional architectures of schizophrenia and other complex diseases using fast variance components analysis

• Downloaded 3,049 times
• Download rankings, all-time:
  • Site-wide: 1,805 out of 89,274
  • In genetics: 137 out of 4,618
• Year to date:
  • Site-wide: 52,798 out of 89,274
• Since beginning of last month:
  • Site-wide: 32,231 out of 89,274

Haplotypes of common SNPs can explain missing heritability of complex diseases

• Downloaded 3,008 times
• Download rankings, all-time:
  • Site-wide: 1,846 out of 89,274
  • In genetics: 141 out of 4,618
• Year to date:
  • Site-wide: 57,006 out of 89,274
• Since beginning of last month:
  • Site-wide: 67,697 out of 89,274

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

• Downloaded 2,506 times
• Download rankings, all-time:
  • Site-wide: 2,505 out of 89,274
  • In genomics: 477 out of 5,695
• Year to date:
  • Site-wide: 65,763 out of 89,274
• Since beginning of last month:
  • Site-wide: 65,300 out of 89,274

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

• Downloaded 1,681 times
• Download rankings, all-time:
  • Site-wide: 4,851 out of 89,274
  • In genetics: 361 out of 4,618
• Year to date:
  • Site-wide: 63,497 out of 89,274
• Since beginning of last month:
  • Site-wide: 83,472 out of 89,274

Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders

• Downloaded 1,014 times
• Download rankings, all-time:
  • Site-wide: 11,238 out of 89,274
  • In genetics: 763 out of 4,618
• Year to date:
  • Site-wide: 6,060 out of 89,274
• Since beginning of last month:
  • Site-wide: 7,054 out of 89,274

Medical consequences of pathogenic CNVs in adults: Analysis of the UK Biobank

• Downloaded 982 times
• Download rankings, all-time:
  • Site-wide: 11,811 out of 89,274
  • In genomics: 1,644 out of 5,695
• Year to date:
  • Site-wide: 25,037 out of 89,274
• Since beginning of last month:
  • Site-wide: 59,106 out of 89,274

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 767 times
• Download rankings, all-time:
  • Site-wide: 17,354 out of 89,274
  • In genetics: 1,112 out of 4,618
• Year to date:
  • Site-wide: 51,832 out of 89,274
• Since beginning of last month:
  • Site-wide: 71,527 out of 89,274

Using genetics to examine a general liability to childhood psychopathology

• Downloaded 648 times
• Download rankings, all-time:
  • Site-wide: 22,256 out of 89,274
  • In genetics: 1,401 out of 4,618
• Year to date:
  • Site-wide: 51,176 out of 89,274
• Since beginning of last month:
  • Site-wide: 49,508 out of 89,274

Association between schizophrenia and both loss of function and missense mutations in paralog conserved sites of voltage-gated sodium channels

• Downloaded 640 times
• Download rankings, all-time:
  • Site-wide: 22,615 out of 89,274
  • In genetics: 1,424 out of 4,618
• Year to date:
  • Site-wide: 56,867 out of 89,274
• Since beginning of last month:
  • Site-wide: 50,187 out of 89,274

Analyses of rare and common alleles in parent-proband trios implicate rare missense variants in SLC6A1 in schizophrenia and confirm the involvement of loss of function intolerant and neurodevelopmental disorder genes.

• Downloaded 465 times
• Download rankings, all-time:
  • Site-wide: 34,156 out of 89,274
  • In genetics: 2,029 out of 4,618
• Year to date:
  • Site-wide: 37,989 out of 89,274
• Since beginning of last month:
  • Site-wide: 40,646 out of 89,274

Genetic association of FMRP targets with psychiatric disorders

• Downloaded 304 times
• Download rankings, all-time:
  • Site-wide: 52,509 out of 89,274
  • In neuroscience: 9,249 out of 15,884
• Year to date:
  • Site-wide: 8,636 out of 89,274
• Since beginning of last month:
  • Site-wide: 14,953 out of 89,274

Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by mutation of the psychiatric risk gene Cacna1c

• Downloaded 112 times
• Download rankings, all-time:
  • Site-wide: 82,109 out of 89,274
  • In neuroscience: 14,670 out of 15,884
• Year to date:
  • Site-wide: 34,437 out of 89,274
• Since beginning of last month:
  • Site-wide: 4,527 out of 89,274