Author: Tetsuro Hirose

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Preprints

Functional Annotation of Human Long Non-Coding RNAs via Molecular Phenotyping

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AGO1 in association with NEAT1 lncRNA contributes to nuclear and 3D chromatin architecture in human cells

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The lncRNA NEAT1_1 is dispensable for normal tissue homeostasis and cancer cell growth

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  • In molecular biology: 873
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LncRNA-dependent nuclear stress bodies promote intron retention through SR protein phosphorylation

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SPF45/RBM17-dependent, but not U2AF-dependent, splicing in human short introns

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  • In molecular biology: 1,184
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Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice

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  • In neuroscience: 8,408
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Forced isoform switching of Neat1_1 to Neat1_2 leads to the loss of Neat1_1 and the hyperformation of paraspeckles but does not affect the development and growth of mice

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  • In molecular biology: 2,811
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Paraspeckles are constructed as block copolymer micelles through microphase separation

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Nascent ribosomal RNA acts as surfactant that suppresses growth of fibrillar centers in nucleolus

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  • In biophysics: 5,245
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Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model

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  • In biochemistry: 4,016
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Triblock copolymer micelle model of spherical paraspeckles

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  • In biophysics: 5,957
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