Author: Wei Xu

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Preprints

Multi-platform discovery of haplotype-resolved structural variation in human genomes

• Downloaded 8,336 times
• Download rankings, all-time:
  • Site-wide: 949
  • In genomics: 84
• Year to date:
  • Site-wide: 46,200
• Since beginning of last month:
  • Site-wide: None

Genomewide association study identifies 30 loci associated with bipolar disorder

• Downloaded 7,266 times
• Download rankings, all-time:
  • Site-wide: 1,132
  • In genetics: 38
• Year to date:
  • Site-wide: 16,098
• Since beginning of last month:
  • Site-wide: 13,777

Inhibition of SARS-CoV-2 infection (previously 2019-nCoV) by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

• Downloaded 5,842 times
• Download rankings, all-time:
  • Site-wide: 1,503
  • In microbiology: 126
• Year to date:
  • Site-wide: 14,028
• Since beginning of last month:
  • Site-wide: 21,117

Stability of the COVID-19 virus under wet, dry and acidic conditions

• Downloaded 4,209 times
• Download rankings, all-time:
  • Site-wide: 2,373
  • In infectious diseases: 498
• Year to date:
  • Site-wide: 705
• Since beginning of last month:
  • Site-wide: 998

AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system in four weeks

• Downloaded 3,306 times
• Download rankings, all-time:
  • Site-wide: 3,368
  • In health informatics: 20
• Year to date:
  • Site-wide: 6,369
• Since beginning of last month:
  • Site-wide: 5,741

Mental health status and coping strategy of medical workers in China during The COVID-19 outbreak

• Downloaded 3,113 times
• Download rankings, all-time:
  • Site-wide: 3,694
  • In psychiatry and clinical psychology: 10
• Year to date:
  • Site-wide: 11,558
• Since beginning of last month:
  • Site-wide: 10,064

Recapitulation of SARS-CoV-2 Infection and Cholangiocyte Damage with Human Liver Organoids

• Downloaded 2,409 times
• Download rankings, all-time:
  • Site-wide: 5,336
  • In cell biology: 105
• Year to date:
  • Site-wide: 22,020
• Since beginning of last month:
  • Site-wide: 23,325

The S1/S2 boundary of SARS-CoV-2 spike protein modulates cell entry pathways and transmission

• Downloaded 1,972 times
• Download rankings, all-time:
  • Site-wide: 7,100
  • In microbiology: 391
• Year to date:
  • Site-wide: 1,747
• Since beginning of last month:
  • Site-wide: 1,826

Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights

• Downloaded 1,557 times
• Download rankings, all-time:
  • Site-wide: 10,158
  • In psychiatry and clinical psychology: 32
• Year to date:
  • Site-wide: 2,739
• Since beginning of last month:
  • Site-wide: 3,393

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,447 times
• Download rankings, all-time:
  • Site-wide: 11,307
  • In genomics: 1,257
• Year to date:
  • Site-wide: 60,391
• Since beginning of last month:
  • Site-wide: 54,882

Targeting glutamine metabolism enhances tumor specific immunity by inhibiting the generation of MDSCs and reprogramming tumor associated macrophages

• Downloaded 1,017 times
• Download rankings, all-time:
  • Site-wide: 19,239
  • In immunology: 533
• Year to date:
  • Site-wide: 48,624
• Since beginning of last month:
  • Site-wide: 45,484

Base editing in Streptomyces with Cas9-deaminase fusions

• Downloaded 789 times
• Download rankings, all-time:
  • Site-wide: 27,583
  • In microbiology: 1,615
• Year to date:
  • Site-wide: 41,700
• Since beginning of last month:
  • Site-wide: 66,952

Feasibility and Safety of Perioperative Chemotherapy with Fluorouracil plus Leucovorin, Oxaliplatin, and Docetaxel (FLOT) for Locally-Advanced Gastric Cancer Patients in China

• Downloaded 688 times
• Download rankings, all-time:
  • Site-wide: 33,317
  • In oncology: 34
• Year to date:
  • Site-wide: 11,745
• Since beginning of last month:
  • Site-wide: 12,416

Intronic heterochromatin prevents cryptic transcription initiation in Arabidopsis

• Downloaded 664 times
• Download rankings, all-time:
  • Site-wide: 34,981
  • In plant biology: 733
• Year to date:
  • Site-wide: 100,711
• Since beginning of last month:
  • Site-wide: None

What is the evidence for transmission of COVID-19 by children in schools? A living systematic review

• Downloaded 657 times
• Download rankings, all-time:
  • Site-wide: 35,437
  • In epidemiology: 1,714
• Year to date:
  • Site-wide: 18,824
• Since beginning of last month:
  • Site-wide: None

A Chemical Probe of CARM1 Alters Epigenetic Plasticity against Breast Cancer Cell Invasion

• Downloaded 629 times
• Download rankings, all-time:
  • Site-wide: 37,519
  • In biochemistry: 925
• Year to date:
  • Site-wide: 112,761
• Since beginning of last month:
  • Site-wide: None

Clinically applicable histopathological diagnosis system for gastric cancer detection using deep learning

• Downloaded 566 times
• Download rankings, all-time:
  • Site-wide: 42,900
  • In pathology: 190
• Year to date:
  • Site-wide: 58,644
• Since beginning of last month:
  • Site-wide: None

DNNBrain: a unifying toolbox for mapping deep neural networks and brains

• Downloaded 527 times
• Download rankings, all-time:
  • Site-wide: 46,749
  • In neuroscience: 6,847
• Year to date:
  • Site-wide: 47,226
• Since beginning of last month:
  • Site-wide: 48,294

Genome and community-level interaction insights on wide carbon utilizing and element cycling function of Hydrothermarchaeota from hydrothermal sediment

• Downloaded 474 times
• Download rankings, all-time:
  • Site-wide: 52,907
  • In ecology: 1,402
• Year to date:
  • Site-wide: 70,196
• Since beginning of last month:
  • Site-wide: 53,453

Physical activity, BMI and COVID-19: an observational and Mendelian randomisation study

• Downloaded 396 times
• Download rankings, all-time:
  • Site-wide: 63,771
  • In infectious diseases: 2,790
• Year to date:
  • Site-wide: 68,467
• Since beginning of last month:
  • Site-wide: 61,393

Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide

• Downloaded 374 times
• Download rankings, all-time:
  • Site-wide: 67,168
  • In microbiology: 4,561
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: None

Interactions Between Molecular Chaperone P20 And Cyt2Ba7 Toxin In Bacillus thuringiensis

• Downloaded 354 times
• Download rankings, all-time:
  • Site-wide: 70,549
  • In microbiology: 4,829
• Year to date:
  • Site-wide: 104,127
• Since beginning of last month:
  • Site-wide: 105,584

Cold Response of the Mediterranean fruit fly (Ceratitis capitata) in the Lab Diet

• Downloaded 340 times
• Download rankings, all-time:
  • Site-wide: 72,986
  • In zoology: 272
• Year to date:
  • Site-wide: 107,071
• Since beginning of last month:
  • Site-wide: None

A negative feedback mechanism in the insulin-regulated glucose homeostasis in Japanese flounder Paralichthys olivaceus by two ways of glucose administration

• Downloaded 322 times
• Download rankings, all-time:
  • Site-wide: 76,312
  • In biochemistry: 2,160
• Year to date:
  • Site-wide: 60,962
• Since beginning of last month:
  • Site-wide: 87,421

Dragon III: Neoadjuvant Chemotherapy FLOT versus SOX for Gastric Cancer

• Downloaded 312 times
• Download rankings, all-time:
  • Site-wide: 78,265
  • In oncology: 107
• Year to date:
  • Site-wide: 30,909
• Since beginning of last month:
  • Site-wide: 49,058

Transcriptional elongation machinery controls vulnerability of breast cancer cells to PRC2 inhibitors

• Downloaded 298 times
• Download rankings, all-time:
  • Site-wide: 81,043
  • In cancer biology: 2,420
• Year to date:
  • Site-wide: 53,167
• Since beginning of last month:
  • Site-wide: 43,965

Extrinsic and Intrinsic Dynamics in Movement Intermittency

• Downloaded 272 times
• Download rankings, all-time:
  • Site-wide: 86,447
  • In neuroscience: 13,428
• Year to date:
  • Site-wide: 122,571
• Since beginning of last month:
  • Site-wide: 102,613

Oncoprotein CoAA repeats interact with RNA polymerase II CTD repeats

• Downloaded 245 times
• Download rankings, all-time:
  • Site-wide: 92,238
  • In biochemistry: 2,690
• Year to date:
  • Site-wide: 78,619
• Since beginning of last month:
  • Site-wide: 53,569

A Missense Point Mutation in Nerve Growth Factor (NGFR100W) Results in Selective Peripheral Sensory Neuropathy

• Downloaded 220 times
• Download rankings, all-time:
  • Site-wide: 97,653
  • In neuroscience: 15,265
• Year to date:
  • Site-wide: 70,833
• Since beginning of last month:
  • Site-wide: 65,757

Characterization of DNA hydroxymethylation in hypothalamus of elderly mice with postoperative cognitive dysfunction

• Downloaded 209 times
• Download rankings, all-time:
  • Site-wide: 100,070
  • In neuroscience: 15,638
• Year to date:
  • Site-wide: 122,635
• Since beginning of last month:
  • Site-wide: 105,627

Early and Midterm Outcomes of Transcatheter Aortic-Valve Replacement with Balloon-Expandable Versus Self-Expanding Valves: A Systematic Review and Meta-Analysis

• Downloaded 137 times
• Download rankings, all-time:
  • Site-wide: 114,588
  • In cardiovascular medicine: 271
• Year to date:
  • Site-wide: 67,239
• Since beginning of last month:
  • Site-wide: 90,637

Quantitative Control of Noise in Mammalian Gene Expression by Dynamic Histone Regulations

• Downloaded 106 times
• Download rankings, all-time:
  • Site-wide: 120,246
  • In molecular biology: 3,639
• Year to date:
  • Site-wide: 41,414
• Since beginning of last month:
  • Site-wide: None

Sterol 14α-demethylase is vital for mitochondrial functions and stress tolerance in Leishmania major

• Downloaded 96 times
• Download rankings, all-time:
  • Site-wide: 121,952
  • In microbiology: 9,369
• Year to date:
  • Site-wide: 102,908
• Since beginning of last month:
  • Site-wide: 104,699