Author: Wei Wang

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Preprints

Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia

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Association of Visual Impairment with Risk for Future Parkinson's Disease

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Comorbidity and its impact on 1,590 patients with COVID-19 in China: A Nationwide Analysis

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  • Site-wide: 234
  • In respiratory medicine: 3
• Year to date:
  • Site-wide: 5,742
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  • Site-wide: 3,605

Age profile of susceptibility, mixing, and social distancing shape the dynamics of the novel coronavirus disease 2019 outbreak in China

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  • Site-wide: 666
  • In epidemiology: 99
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  • Site-wide: 25,204

COVID-19 in Wuhan: Immediate Psychological Impact on 5062 Health Workers

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  • Site-wide: 925
  • In psychiatry and clinical psychology: 3
• Year to date:
  • Site-wide: 966
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  • Site-wide: 592

Environmental contamination of the SARS-CoV-2 in healthcare premises: An urgent call for protection for healthcare workers

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  • Site-wide: 980
  • In infectious diseases: 262
• Year to date:
  • Site-wide: 4,274
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  • Site-wide: 7,520

Global profiling of SARS-CoV-2 specific IgG/ IgM responses of convalescents using a proteome microarray

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  • Site-wide: 1,387
  • In infectious diseases: 342
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  • Site-wide: 16,220

Modified TCA/acetone precipitation of plant proteins for proteomic analysis

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  • Site-wide: 1,511
  • In biochemistry: 22
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  • Site-wide: 2,082

Is Oculudentavis a bird or even archosaur?

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  • Site-wide: 1,745
  • In evolutionary biology: 24
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  • Site-wide: 10,682

Systematic mapping of chromatin state landscapes during mouse development

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  • Site-wide: 1,964
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Detection of 2019 novel coronavirus in semen and testicular biopsy specimen of COVID-19 patients

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  • Site-wide: 2,287
  • In infectious diseases: 450
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  • Site-wide: 27,275

CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos

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  • Site-wide: 2,481
  • In developmental biology: 21
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  • Site-wide: 1,990
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  • Site-wide: 3,051

Evolving epidemiology of novel coronavirus diseases 2019 and possible interruption of local transmission outside Hubei Province in China: a descriptive and modeling study

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  • Site-wide: 2,735
  • In infectious diseases: 500
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  • Site-wide: 26,798

The Use of Adjuvant Therapy in Preventing Progression to Severe Pneumonia in Patients with Coronavirus Disease 2019: A Multicenter Data Analysis

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  • Site-wide: 3,895
  • In infectious diseases: 618
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  • Site-wide: 65,489

A single cell transcriptional roadmap for cardiopharyngeal fate diversification

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  • Site-wide: 4,191
  • In developmental biology: 46
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  • Site-wide: 36,962
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  • Site-wide: 15,188

Early Prediction of Disease Progression in 2019 Novel Coronavirus Pneumonia Patients Outside Wuhan with CT and Clinical Characteristics

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  • Site-wide: 4,758
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Infectivity, susceptibility, and risk factors associated with SARS-CoV-2 transmission under intensive contact tracing in Hunan, China

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  • Site-wide: 5,058
  • In infectious diseases: 737
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  • Site-wide: 2,484
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  • Site-wide: 1,423

Assessment of single cell RNA-seq normalization methods

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  • Site-wide: 5,525
  • In bioinformatics: 675
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  • Site-wide: 87,809

Case fatality risk of novel coronavirus diseases 2019 in China

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  • Site-wide: 6,886
  • In infectious diseases: 867
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  • Site-wide: 48,004

Establishment In Culture Of Expanded Potential Stem Cells

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  • Site-wide: 8,288
  • In developmental biology: 109
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  • Site-wide: 50,548
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  • Site-wide: 21,865

Spatially clustered loci with multiple enhancers are frequent targets of HIV-1

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  • Site-wide: 8,452
  • In genomics: 983
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  • Site-wide: 89,072

Persistent SARS-CoV-2 presence is companied with defects in adaptive immune system in non-severe COVID-19 patients

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  • Site-wide: 8,945
  • In infectious diseases: 1,001
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  • Site-wide: 107,652

The Effectiveness of China’s National Forest Protection Program and National-level Nature Reserves, 2000 to 2010

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  • Site-wide: 9,841
  • In ecology: 141
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  • Site-wide: 43,009

In-Vivo Toxicity Studies and In-Vitro Inactivation of SARS-CoV-2 by Povidone-iodine In-situ Gel Forming Formulations

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  • Site-wide: 10,231
  • In microbiology: 550
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  • Site-wide: 3,567
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  • Site-wide: 3,044

GSKB: A gene set database for pathway analysis in mouse

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  • Site-wide: 10,585
  • In bioinformatics: 1,351
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  • Site-wide: 39,681

Identification of DNA motifs that regulate DNA methylation

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  • Site-wide: 12,469
  • In bioinformatics: 1,572
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  • Site-wide: 70,965

Single-cell transcriptome profiling of the Ciona larval brain

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  • Site-wide: 13,569
  • In developmental biology: 223
• Year to date:
  • Site-wide: 41,407
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  • Site-wide: 52,617

SHP2 Inhibition Abrogates Adaptive Resistance to KRASG12C-Inhibition and Remodels the Tumor Microenvironment of KRAS-Mutant Tumors

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  • Site-wide: 13,778
  • In cancer biology: 303
• Year to date:
  • Site-wide: 4,093
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  • Site-wide: 3,189

Assessing the measurement transfer function of single-cell RNA sequencing

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  • Site-wide: 15,954
  • In genomics: 1,713
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  • Site-wide: None
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  • Site-wide: 98,707

Hybrid origins and the earliest stages of diploidization in the highly successful recent polyploid Capsella bursa-pastoris

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  • Site-wide: 16,576
  • In evolutionary biology: 709
• Year to date:
  • Site-wide: 42,874
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  • Site-wide: 66,082

Finding de novo methylated DNA motifs

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  • Site-wide: 17,867
  • In bioinformatics: 2,213
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  • Site-wide: None
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  • Site-wide: 117,513

TahcoRoll: An Efficient Approach for Signature Profiling in Genomic Data through Variable-Length k-mers

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  • Site-wide: 18,012
  • In bioinformatics: 2,227
• Year to date:
  • Site-wide: 24,565
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  • Site-wide: 53,760

The RNA-binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria

• Downloaded 932 times
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  • Site-wide: 20,116
  • In genetics: 1,017
• Year to date:
  • Site-wide: 61,090
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  • Site-wide: 93,944

Molecular Crowding Tunes Material States of Ribonucleoprotein Condensates

• Downloaded 891 times
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  • Site-wide: 21,429
  • In biophysics: 610
• Year to date:
  • Site-wide: 30,566
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  • Site-wide: 15,851

Loss of SATB1 Induces a p21 Dependent Cellular Senescence Phenotype in Dopaminergic Neurons

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  • Site-wide: 21,836
  • In neuroscience: 2,881
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  • Site-wide: 30,353
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  • Site-wide: 42,053

Co-expression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders

• Downloaded 838 times
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  • Site-wide: 23,439
  • In genetics: 1,191
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  • Site-wide: 75,381

Role of short-chain fatty acids in the gut-brain axis in schizophrenia: contribution to immune activation and pathophysiology in humans and mice

• Downloaded 827 times
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  • Site-wide: 23,878
  • In neuroscience: 3,192
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  • Site-wide: 29,844

Full-genome evolutionary histories of selfing, splitting and selection in Caenorhabditis

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  • Site-wide: 24,091
  • In genomics: 2,360
• Year to date:
  • Site-wide: 54,288
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  • Site-wide: 63,957

A nuclear hormone receptor and lipid metabolism axis are required for the maintenance and regeneration of reproductive organs

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  • Site-wide: 25,426
  • In developmental biology: 521
• Year to date:
  • Site-wide: 35,553
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  • Site-wide: 30,582

Identification of gut microbiome markers for schizophrenia delineates a potential role of Streptococcus

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  • Site-wide: 25,943
  • In microbiology: 1,492
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  • Site-wide: 80,852

Association of 25 hydroxyvitamin D concentration with risk of COVID-19: a Mendelian randomization study

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  • Site-wide: 26,763
  • In infectious diseases: 1,676
• Year to date:
  • Site-wide: 14,339
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  • Site-wide: 18,223

Association of Personal Protective Equipment Use with Successful Protection Against COVID-19 Infection Among Health Care Workers

• Downloaded 759 times
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  • Site-wide: 26,871
  • In epidemiology: 1,358
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  • Site-wide: None
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  • Site-wide: 43,053

Molecular evolution across developmental time reveals rapid divergence in early embryogenesis

• Downloaded 729 times
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  • Site-wide: 28,459
  • In evolutionary biology: 1,454
• Year to date:
  • Site-wide: 36,949
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  • Site-wide: 79,710

An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time

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  • Site-wide: 29,474
  • In developmental biology: 633
• Year to date:
  • Site-wide: 67,312
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  • Site-wide: 74,118

Cardiac Structural and Functional Characteristics in Patients with Coronavirus Disease 2019: A Serial Echocardiographic Study

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  • Site-wide: 29,709
  • In cardiovascular medicine: 43
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  • Site-wide: 10,063

Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients

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  • Site-wide: 29,896
  • In infectious diseases: 1,768
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  • Site-wide: 31,137

Systems-level identification of transcription factors critical for mouse embryonic development

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  • Site-wide: 30,113
  • In bioinformatics: 3,477
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  • Site-wide: 61,669
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  • Site-wide: 116,378

Computational Study of Ions and Water Permeation and Transportation Mechanisms of the SARS-CoV-2 Pentameric E Protein Channel

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  • Site-wide: 30,423
  • In biophysics: 967
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  • Site-wide: 58,445

Contemporary circulating enterovirus D68 strains show differential viral entry and replication in human neuronal cells

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  • Site-wide: 31,555
  • In microbiology: 1,842
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  • Site-wide: 82,958

Systematic identification of cooperation between DNA binding proteins in 3D space

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  • Site-wide: 32,674
  • In bioinformatics: 3,724
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  • Site-wide: 113,030

Paralogues of the PXY and ER receptor kinases enforce radial patterning in plant vascular tissue.

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  • Site-wide: 32,758
  • In plant biology: 688
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  • Site-wide: 43,410
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  • Site-wide: 37,937

MiniScrub: de novo long read scrubbing using approximate alignment and deep learning

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  • Site-wide: 34,147
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  • Site-wide: 115,750

Lasagna: Multifaceted Protein-Protein Interaction Prediction Based on Siamese Residual RCNN

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  • Site-wide: 35,704
  • In bioinformatics: 4,002
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  • Site-wide: 31,090
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  • Site-wide: 26,911

Symptom-level genetic modelling identifies novel risk loci and unravels the shared genetic architecture of anxiety and depression

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  • Site-wide: 36,963
  • In genetic and genomic medicine: 97
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  • Site-wide: 48,153
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  • Site-wide: 40,325

Motto: Representing motifs in consensus sequences with minimum information loss

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  • Site-wide: 38,661
  • In bioinformatics: 4,274
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  • Site-wide: 16,111
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  • Site-wide: 23,305

Prophase removal of chromosome-associated RNAs facilitates anaphase chromosome segregation

• Downloaded 546 times
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  • Site-wide: 41,370
  • In cell biology: 1,759
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  • Site-wide: 13,447
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  • Site-wide: 43,759

Interplay Between Short-range Attraction and Long-range Repulsion Controls Reentrant Liquid Condensation of Ribonucleoprotein-RNA Complexes

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  • Site-wide: 41,458
  • In biophysics: 1,415
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  • Site-wide: 42,420
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  • Site-wide: 47,924

Nationwide population genetic screening improves outcomes of newborn screening for hearing loss in China

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  • Site-wide: 42,827
  • In genetics: 2,111
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  • Site-wide: 86,006

Genome-wide study identifies association between HLA-B*55:01 and penicillin allergy

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  • Site-wide: 43,409
  • In genetics: 2,143
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  • Site-wide: 24,063
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  • Site-wide: 37,427

Global variability of the human IgG glycome

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  • Site-wide: 43,517
  • In biochemistry: 1,131
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  • Site-wide: 48,113
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  • Site-wide: 57,183

Xist Intron 1 Repression by TALE Transcriptional Factor Improves Somatic Cell Reprogamming in Mice

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  • Site-wide: 44,171
  • In developmental biology: 1,073
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  • Site-wide: 57,150
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  • Site-wide: 51,674

Mechanisms of integrin αVβ5 clustering in flat clathrin lattices

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  • Site-wide: 45,449
  • In cell biology: 1,975
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  • Site-wide: 36,178
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  • Site-wide: 35,521

Global, regional, and national estimates of target population sizes for COVID-19 vaccination

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  • Site-wide: 47,801
  • In infectious diseases: 2,238
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  • Site-wide: 7,658
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  • Site-wide: 3,632

Genome structure predicts modular transcriptome responses to genetic and environmental conditions

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  • Site-wide: 48,322
  • In genomics: 3,874
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Identification of 67 pleiotropic genes for seven autoimmune diseases using multivariate statistical analysis

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  • Site-wide: 48,700
  • In genetics: 2,382
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  • Site-wide: 63,535

Neurogenin regulates effectors of migratory neuron cell behaviors in Ciona

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  • Site-wide: 49,589
  • In developmental biology: 1,240
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  • Site-wide: 26,112
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  • Site-wide: 83,745

Cell Cycle, Energy Metabolism and DNA Repair Pathways in Cancer Cells are Suppressed by Compound Kushen Injection.

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  • Site-wide: 50,287
  • In cancer biology: 1,426
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  • Site-wide: 104,416

JEDI: Circular RNA Prediction based on Junction Encoders and Deep Interaction among Splice Sites

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  • Site-wide: 31,576

Non-parametric and semi-parametric support estimation using SEquential RESampling random walks on biomolecular sequences

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  • Site-wide: 51,246
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Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure

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  • Site-wide: 51,582
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Association between Alzheimer's disease and COVID-19: A bidirectional Mendelian randomization

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  • Site-wide: 51,821
  • In genetic and genomic medicine: 138
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  • Site-wide: 17,527
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  • Site-wide: 19,698

Screening of FDA-approved Drugs and Identification of Novel Lassa Virus Entry Inhibitors

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  • Site-wide: 55,193
  • In microbiology: 3,564
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  • Site-wide: 49,489
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  • Site-wide: 84,480

Fecal microbiota as a non-invasive biomarker to predict the tissue iron accumulation in intestine epithelial cells and liver

• Downloaded 415 times
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  • Site-wide: 56,355
  • In microbiology: 3,663
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  • Site-wide: 27,625

Targeted mutations on 3D hub loci alter spatial interaction environment

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  • Site-wide: 56,955
  • In biophysics: 2,068
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  • Site-wide: 94,167

Mutation effect estimation on protein-protein interactions using deep contextualized representation learning

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  • Site-wide: 80,671

Bacterial Glycogen as a Durable Energy Reserve Contributing to Persistence: An Updated Bibliography and Mathematical Model

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  • Site-wide: 61,198
  • In microbiology: 4,038
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  • Site-wide: 39,896

The Effect of Compound Kushen Injection on Cancer Cells: Integrated Identification of Candidate Molecular Mechanisms.

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  • Site-wide: 62,180
  • In pharmacology and toxicology: 377
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  • Site-wide: 56,156

Cell cycle-gated feedback control mediates desensitization to interferon stimulation

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  • Site-wide: 62,367
  • In systems biology: 1,556
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  • Site-wide: 95,148

Uncovering Medical Insights from Vast Amounts of Biomedical Data in Clinical Case Reports

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  • Site-wide: 63,512
  • In bioinformatics: 6,234
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  • Site-wide: 64,481

Loss of Dnmt3a dependent methylation in inhibitory neurons impairs neural function through a mechanism that impacts Rett syndrome

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  • Site-wide: 63,863
  • In neuroscience: 9,764
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  • Site-wide: 105,708

Chemical, physical and biological triggers of Bcl-xL-mediated apoptosis

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  • Site-wide: 64,344
  • In cancer biology: 1,871
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  • Site-wide: 25,718
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  • Site-wide: 27,676

Build a Better Bootstrap and the RAWR Shall Beat a Random Path to Your Door: Phylogenetic Support Estimation Revisited

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  • Site-wide: 66,312
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  • Site-wide: 15,662

Dual functions of Discoidin domain receptor coordinate cell-matrix adhesion and collective polarity in migratory cardiopharyngeal progenitors

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  • Site-wide: 67,430
  • In developmental biology: 1,791
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  • Site-wide: 89,071

Human Cytomegalovirus Immediate-Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus

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  • Site-wide: 67,582
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  • Site-wide: 85,857

Genome-wide association analysis and replication in 810,625 individuals identifies novel therapeutic targets for varicose veins

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  • Site-wide: 67,826
  • In genetics: 3,235
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  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 56,774

Genome-wide analysis identifies cis-acting elements regulating mRNA polyadenylation and translation during vertebrate oocyte maturation

• Downloaded 341 times
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  • Site-wide: 67,932
  • In genomics: 4,794
• Year to date:
  • Site-wide: 60,390
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  • Site-wide: 47,609

Bio-JOIE: Joint Representation Learning of Biological Knowledge Bases

• Downloaded 336 times
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  • Site-wide: 68,821
  • In bioinformatics: 6,592
• Year to date:
  • Site-wide: 11,994
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  • Site-wide: 25,417

Single-cell Characterization of Acute Myeloid Leukemia and its Microenvironment Following PD-1 Blockade Based Therapy

• Downloaded 319 times
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  • Site-wide: 71,817
  • In cancer biology: 2,125
• Year to date:
  • Site-wide: 17,324
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  • Site-wide: 8,761

Contextual Regression: An Accurate and Conveniently Interpretable Nonlinear Model for Mining Discovery from Scientific Data

• Downloaded 313 times
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  • Site-wide: 72,760
  • In bioinformatics: 6,836
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  • Site-wide: None
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  • Site-wide: 117,054

DTI-CDF: a CDF model towards the prediction of DTIs based on hybrid features

• Downloaded 311 times
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  • Site-wide: 73,257
  • In bioinformatics: 6,859
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  • Site-wide: None
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  • Site-wide: 104,228

Structural basis for transfer RNA mimicry by a bacterial Y RNA

• Downloaded 305 times
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  • Site-wide: 74,321
  • In biochemistry: 2,132
• Year to date:
  • Site-wide: 68,334
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  • Site-wide: 79,653

Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis

• Downloaded 292 times
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  • Site-wide: 76,750
  • In pharmacology and toxicology: 508
• Year to date:
  • Site-wide: 60,186
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  • Site-wide: 41,358

Latent defense response to non-pathogenic microbial factors impairs plant-rhizobacteria mutualism

• Downloaded 285 times
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  • Site-wide: 78,199
  • In plant biology: 2,094
• Year to date:
  • Site-wide: 35,249
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  • Site-wide: 25,956

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease

• Downloaded 281 times
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  • Site-wide: 78,944
  • In microbiology: 5,499
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  • Site-wide: 21,682
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  • Site-wide: 16,268

NF-κB modifies the mammalian circadian clock through interaction with the core clock protein BMAL1

• Downloaded 278 times
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  • Site-wide: 79,492
  • In molecular biology: 2,368
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  • Site-wide: None
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  • Site-wide: 27,645

A new strategy for identifying mechanisms of drug-drug interaction using transcriptome analysis: Compound Kushen injection as a proof of principle

• Downloaded 277 times
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  • Site-wide: 79,634
  • In pharmacology and toxicology: 538
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  • Site-wide: None
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  • Site-wide: 117,723

Comparative Transcriptomes Analysis of Taenia pisiformis at Different Development Stages

• Downloaded 270 times
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  • Site-wide: 81,033
  • In molecular biology: 2,420
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  • Site-wide: None
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  • Site-wide: 108,615

Role of Water Mediated Interactions in Calcium-Coupled Allostery of Calmodulin Domains

• Downloaded 270 times
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  • Site-wide: 81,083
  • In biochemistry: 2,370
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  • Site-wide: 68,968
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  • Site-wide: 44,234

Exploring the Changing Landscape of Cell-to-Cell Variation After CTCF Knockdown via Single Cell RNA-seq

• Downloaded 267 times
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  • Site-wide: 81,734
  • In genomics: 5,329
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  • Site-wide: None
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  • Site-wide: 52,601

Sulforaphane modulates microRNA expression in colon cancer cells to implicate the regulation of oncogenes CDC25A, HMGA2 and MYC

• Downloaded 265 times
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  • Site-wide: 82,082
  • In cancer biology: 2,482
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  • Site-wide: None
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  • Site-wide: 105,029

Systematic profiling of SARS-CoV-2 specific IgG epitopes at single amino acid resolution

• Downloaded 263 times
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  • Site-wide: 82,601
  • In epidemiology: 3,318
• Year to date:
  • Site-wide: 12,937
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  • Site-wide: 30,897

Recovery of Consciousness and Cognition after General Anesthesia in Humans

• Downloaded 261 times
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  • Site-wide: 83,071
  • In neuroscience: 12,905
• Year to date:
  • Site-wide: 23,413
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  • Site-wide: 25,149

Androgen Promotes Differentiation of PLZF+ Spermatogonia pool via Indirect Regulatory Pattern

• Downloaded 250 times
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  • Site-wide: 85,245
  • In developmental biology: 2,380
• Year to date:
  • Site-wide: 61,824
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  • Site-wide: 52,973

Autophagy Decreases Alveolar Epithelial Cell Injury by Suppressing the NF-κB Signaling Pathway and Regulating the Release of Inflammatory Mediators

• Downloaded 249 times
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  • Site-wide: 85,526
  • In cell biology: 3,996
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  • Site-wide: 28,619
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  • Site-wide: 92,736

An Analysis of Outbreak Dynamics and Intervention Effects for COVID-19 Transmission in Europe

• Downloaded 248 times
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  • Site-wide: 85,718
  • In infectious diseases: 2,972
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  • Site-wide: None
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  • Site-wide: 105,100

Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in the murine cardiopharyngeal mesoderm

• Downloaded 244 times
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  • Site-wide: 86,652
  • In developmental biology: 2,402
• Year to date:
  • Site-wide: 1,815
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  • Site-wide: 1,655

Thm2 interacts with paralog, Thm1, and sensitizes to Hedgehog signaling in postnatal skeletogenesis

• Downloaded 228 times
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  • Site-wide: 89,939
  • In developmental biology: 2,484
• Year to date:
  • Site-wide: 65,418
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  • Site-wide: 103,538

Efficacy and Acceptability Comparisons of Cognitive Behavior Therapy, Drugs, and Their Combination for Panic Disorder in Adults: a Network Meta-analysis

• Downloaded 217 times
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  • Site-wide: 92,173
  • In psychiatry and clinical psychology: 324
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  • Site-wide: 52,944
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  • Site-wide: 56,219

Causal associations between COVID-19 and Atrial Fibrillation: A bidirectional Mendelian randomization study

• Downloaded 214 times
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  • Site-wide: 92,814
  • In genetic and genomic medicine: 312
• Year to date:
  • Site-wide: 33,552
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  • Site-wide: 28,757

Testosterone Changes in Female Pandas in Estrus

• Downloaded 211 times
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  • Site-wide: 93,415
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  • Site-wide: 96,140

Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary protein trafficking, Hedgehog signaling and embryogenesis

• Downloaded 209 times
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  • Site-wide: 93,766
  • In genetics: 4,350
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  • Site-wide: 70,209
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  • Site-wide: 110,295

Integrative analysis with expanded DNA methylation data reveals common key regulators and pathways in cancers

• Downloaded 207 times
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  • Site-wide: 94,163
  • In bioinformatics: 8,200
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  • Site-wide: None
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  • Site-wide: 106,118

Experimental Stroke Induces Chronic Gut Dysbiosis and Neuroinflammation in Male Mice

• Downloaded 206 times
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  • Site-wide: 94,431
  • In neuroscience: 14,757
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  • Site-wide: None
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  • Site-wide: 39,015

Association between ocular biometrical parameters and diabetic retinopathy in Chinese adults with type 2 diabetes mellitus

• Downloaded 205 times
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  • Site-wide: 94,731
  • In pathology: 529
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  • Site-wide: None
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  • Site-wide: 90,186

Heterodimerization of UNC-13/RIM regulates synaptic vesicle release probability but not priming

• Downloaded 202 times
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  • Site-wide: 95,248
  • In neuroscience: 14,909
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  • Site-wide: None
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  • Site-wide: 90,498

Loss of tissue non-specific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis

• Downloaded 197 times
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  • Site-wide: 96,486
  • In neuroscience: 15,042
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  • Site-wide: None

A multiethnic GWAS meta-analysis of 585,243 individuals identifies new risk loci associated with cataract and reveals sex-specific effects

• Downloaded 194 times
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  • Site-wide: 97,069
  • In genetic and genomic medicine: 346
• Year to date:
  • Site-wide: 14,396
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  • Site-wide: 37,986

The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in Escherichia coli

• Downloaded 189 times
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  • Site-wide: 98,051
  • In molecular biology: 2,938
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  • Site-wide: None
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  • Site-wide: 89,838

Increased p53 signaling impairs neural differentiation causing HUWE1-promoted intellectual disabilities

• Downloaded 182 times
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  • Site-wide: 99,483
  • In cell biology: 4,642
• Year to date:
  • Site-wide: 50,507
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  • Site-wide: 76,146

Mechanical dysfunction induced by a hypertrophic cardiomyopathy mutation is the primary driver of cellular adaptation

• Downloaded 180 times
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  • Site-wide: 99,918
  • In biophysics: 3,893
• Year to date:
  • Site-wide: 42,069
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  • Site-wide: 49,398

Prediction of LncRNA Encoded Small Peptides in Glioma and The Oligomer Channel Functional Analysis Using in Silico Approaches

• Downloaded 154 times
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  • Site-wide: 104,946
  • In biophysics: 4,099
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  • Site-wide: 16,135
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  • Site-wide: 36,529

Oncogenic Activation of AKT by MAPK6

• Downloaded 142 times
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  • Site-wide: 107,031
  • In cancer biology: 3,357
• Year to date:
  • Site-wide: 39,641
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  • Site-wide: 31,554

The influence of insulin therapy on measurements of optical coherence tomography parameters in diabetic patients without retinopathy

• Downloaded 125 times
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  • Site-wide: 110,027
  • In physiology: 1,261
• Year to date:
  • Site-wide: 41,830
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  • Site-wide: 50,463

Genome-wide identification of long non-coding RNAs in the gravid ectoparasite Varroa destructor

• Downloaded 120 times
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  • Site-wide: 111,002
  • In genomics: 6,264
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  • Site-wide: None
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  • Site-wide: 111,511

Limbal Niche Cells in Three-Dimensional Matrigel Induced Dedifferentiation of Mature Corneal Epithelial Cells toward a Progenitor State

• Downloaded 89 times
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  • Site-wide: 116,234
  • In bioengineering: 2,393
• Year to date:
  • Site-wide: 53,687
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  • Site-wide: 58,916

Brassinosteroids Promote Parenchyma Cell and Secondary Xylem Development in Sugar Beet (Beta vulgaris L.) Root

• Downloaded 70 times
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  • Site-wide: 119,066
  • In plant biology: 3,351
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  • Site-wide: None
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  • Site-wide: 113,373

Screening of Botanical Drugs Against Lassa Virus Entry

• Downloaded 62 times
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  • Site-wide: 120,083
  • In microbiology: 9,248
• Year to date:
  • Site-wide: 55,299
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  • Site-wide: 58,581

Effects of N-linked glycan of Lassa Virus Envelope Glycoprotein on the Immune Response

• Downloaded 54 times
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  • Site-wide: 120,950
  • In microbiology: 9,369
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  • Site-wide: None
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  • Site-wide: 97,872

IFT-A deficiency in juvenile mice impairs biliary development and exacerbates ADPKD liver disease

• Downloaded 51 times
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  • Site-wide: 121,140
  • In genetics: 5,203
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  • Site-wide: None
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  • Site-wide: 72,774

Functional Characterization of a Lassa Virus Fusion Inhibitors Adaptive Mutant

• Downloaded 35 times
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  • Site-wide: 122,047
  • In microbiology: 9,535
• Year to date:
  • Site-wide: 43,430
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  • Site-wide: 16,167

Mechanism through which retrocyclin targets flavivirus multiplication

• Downloaded 18 times
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  • Site-wide: 122,390
  • In microbiology: 9,585
• Year to date:
  • Site-wide: 69,322
• Since beginning of last month:
  • Site-wide: 28,692