Author: Gerome Breen

Downloads per author, site-wide

Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

• Downloaded 9,242 times
• Download rankings, all-time:
  • Site-wide: 314 out of 100,745
  • In genetics: 24 out of 5,016
• Year to date:
  • Site-wide: 11,442 out of 100,745
• Since beginning of last month:
  • Site-wide: 7,788 out of 100,745

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

• Downloaded 5,009 times
• Download rankings, all-time:
  • Site-wide: 867 out of 100,745
  • In genetics: 63 out of 5,016
• Year to date:
  • Site-wide: 11,569 out of 100,745
• Since beginning of last month:
  • Site-wide: 8,787 out of 100,745

A reference panel of 64,976 haplotypes for genotype imputation

• Downloaded 4,539 times
• Download rankings, all-time:
  • Site-wide: 1,031 out of 100,745
  • In genetics: 72 out of 5,016
• Year to date:
  • Site-wide: 70,944 out of 100,745
• Since beginning of last month:
  • Site-wide: 57,790 out of 100,745

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

• Downloaded 4,376 times
• Download rankings, all-time:
  • Site-wide: 1,108 out of 100,745
  • In genomics: 223 out of 6,246
• Year to date:
  • Site-wide: 3,583 out of 100,745
• Since beginning of last month:
  • Site-wide: None out of 100,745

Genetic Identification of Cell Types Underlying Brain Complex Traits Yields Novel Insights Into the Etiology of Parkinson’s Disease

• Downloaded 3,891 times
• Download rankings, all-time:
  • Site-wide: 1,358 out of 100,745
  • In genomics: 279 out of 6,246
• Year to date:
  • Site-wide: 1,747 out of 100,745
• Since beginning of last month:
  • Site-wide: 4,304 out of 100,745

Genetic Identification Of Brain Cell Types Underlying Schizophrenia

• Downloaded 3,539 times
• Download rankings, all-time:
  • Site-wide: 1,588 out of 100,745
  • In genomics: 323 out of 6,246
• Year to date:
  • Site-wide: 35,818 out of 100,745
• Since beginning of last month:
  • Site-wide: 39,877 out of 100,745

The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls

• Downloaded 1,907 times
• Download rankings, all-time:
  • Site-wide: 4,516 out of 100,745
  • In genomics: 745 out of 6,246
• Year to date:
  • Site-wide: 4,883 out of 100,745
• Since beginning of last month:
  • Site-wide: 10,724 out of 100,745

Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits

• Downloaded 1,857 times
• Download rankings, all-time:
  • Site-wide: 4,746 out of 100,745
  • In genetics: 335 out of 5,016
• Year to date:
  • Site-wide: 5,901 out of 100,745
• Since beginning of last month:
  • Site-wide: 4,931 out of 100,745

Applying polygenic risk scoring for psychiatric disorders to a large family with Bipolar Disorder and Major Depressive Disorder

• Downloaded 1,683 times
• Download rankings, all-time:
  • Site-wide: 5,544 out of 100,745
  • In genetics: 388 out of 5,016
• Year to date:
  • Site-wide: 42,166 out of 100,745
• Since beginning of last month:
  • Site-wide: 35,297 out of 100,745

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

• Downloaded 1,513 times
• Download rankings, all-time:
  • Site-wide: 6,651 out of 100,745
  • In genetics: 470 out of 5,016
• Year to date:
  • Site-wide: 12,771 out of 100,745
• Since beginning of last month:
  • Site-wide: 14,599 out of 100,745

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

• Downloaded 1,398 times
• Download rankings, all-time:
  • Site-wide: 7,597 out of 100,745
  • In genomics: 1,160 out of 6,246
• Year to date:
  • Site-wide: 72,685 out of 100,745
• Since beginning of last month:
  • Site-wide: None out of 100,745

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

• Downloaded 1,070 times
• Download rankings, all-time:
  • Site-wide: 11,888 out of 100,745
  • In genetics: 786 out of 5,016
• Year to date:
  • Site-wide: 44,607 out of 100,745
• Since beginning of last month:
  • Site-wide: 46,766 out of 100,745

Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders

• Downloaded 973 times
• Download rankings, all-time:
  • Site-wide: 13,858 out of 100,745
  • In genomics: 1,827 out of 6,246
• Year to date:
  • Site-wide: 93,072 out of 100,745
• Since beginning of last month:
  • Site-wide: None out of 100,745

Examination of the Shared Genetic Basis of Anorexia Nervosa and Obsessive-Compulsive Disorder

• Downloaded 918 times
• Download rankings, all-time:
  • Site-wide: 15,236 out of 100,745
  • In genetics: 968 out of 5,016
• Year to date:
  • Site-wide: 30,484 out of 100,745
• Since beginning of last month:
  • Site-wide: 28,874 out of 100,745

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

• Downloaded 775 times
• Download rankings, all-time:
  • Site-wide: 19,823 out of 100,745
  • In genetics: 1,227 out of 5,016
• Year to date:
  • Site-wide: 70,704 out of 100,745
• Since beginning of last month:
  • Site-wide: None out of 100,745

FORGE: multivariate calculation of gene-wide p-values from Genome-Wide Association Studies Authors and Affiliations

• Downloaded 767 times
• Download rankings, all-time:
  • Site-wide: 20,108 out of 100,745
  • In genetics: 1,246 out of 5,016
• Year to date:
  • Site-wide: 42,930 out of 100,745
• Since beginning of last month:
  • Site-wide: 30,126 out of 100,745

New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

• Downloaded 562 times
• Download rankings, all-time:
  • Site-wide: 31,148 out of 100,745
  • In genomics: 3,145 out of 6,246
• Year to date:
  • Site-wide: 83,454 out of 100,745
• Since beginning of last month:
  • Site-wide: 80,572 out of 100,745

Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.

• Downloaded 520 times
• Download rankings, all-time:
  • Site-wide: 34,337 out of 100,745
  • In genomics: 3,353 out of 6,246
• Year to date:
  • Site-wide: 6,852 out of 100,745
• Since beginning of last month:
  • Site-wide: 8,997 out of 100,745

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

• Downloaded 519 times
• Download rankings, all-time:
  • Site-wide: 34,449 out of 100,745
  • In genetics: 2,008 out of 5,016
• Year to date:
  • Site-wide: 22,476 out of 100,745
• Since beginning of last month:
  • Site-wide: 33,427 out of 100,745

Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

• Downloaded 501 times
• Download rankings, all-time:
  • Site-wide: 36,005 out of 100,745
  • In genetics: 2,086 out of 5,016
• Year to date:
  • Site-wide: 7,289 out of 100,745
• Since beginning of last month:
  • Site-wide: 2,334 out of 100,745

Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

• Downloaded 496 times
• Download rankings, all-time:
  • Site-wide: 36,465 out of 100,745
  • In genetics: 2,105 out of 5,016
• Year to date:
  • Site-wide: 7,392 out of 100,745
• Since beginning of last month:
  • Site-wide: 11,036 out of 100,745

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

• Downloaded 473 times
• Download rankings, all-time:
  • Site-wide: 38,568 out of 100,745
  • In genetics: 2,214 out of 5,016
• Year to date:
  • Site-wide: 34,853 out of 100,745
• Since beginning of last month:
  • Site-wide: 16,681 out of 100,745

Genetic effects on educational attainment in Hungary

• Downloaded 386 times
• Download rankings, all-time:
  • Site-wide: 48,210 out of 100,745
  • In genetics: 2,725 out of 5,016
• Year to date:
  • Site-wide: 10,945 out of 100,745
• Since beginning of last month:
  • Site-wide: 12,084 out of 100,745

Using Major Depression Polygenic Risk Scores to Explore the Depressive Symptom Continuum

• Downloaded 379 times
• Download rankings, all-time:
  • Site-wide: 49,197 out of 100,745
  • In genetics: 2,766 out of 5,016
• Year to date:
  • Site-wide: 11,268 out of 100,745
• Since beginning of last month:
  • Site-wide: None out of 100,745

Genomic Influences on Self-Reported Childhood Maltreatment

• Downloaded 347 times
• Download rankings, all-time:
  • Site-wide: 53,413 out of 100,745
  • In genomics: 4,418 out of 6,246
• Year to date:
  • Site-wide: 51,226 out of 100,745
• Since beginning of last month:
  • Site-wide: 62,862 out of 100,745

Genes associated with neuropsychiatric disease increase vulnerability to abnormal deep grey matter development

• Downloaded 253 times
• Download rankings, all-time:
  • Site-wide: 68,450 out of 100,745
  • In neuroscience: 11,997 out of 17,945
• Year to date:
  • Site-wide: 86,927 out of 100,745
• Since beginning of last month:
  • Site-wide: 76,078 out of 100,745

Evaluation of Polygenic Prediction Methodology within a Reference-Standardized Framework

• Downloaded 125 times
• Download rankings, all-time:
  • Site-wide: 89,635 out of 100,745
  • In genomics: 5,840 out of 6,246
• Year to date:
  • Site-wide: 49,369 out of 100,745
• Since beginning of last month:
  • Site-wide: None out of 100,745