Author: John C Chambers

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Preprints

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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  • Site-wide: 3,747
  • In genetics: 167
• Year to date:
  • Site-wide: 39,415
• Since beginning of last month:
  • Site-wide: 51,372

Identification of type 2 diabetes loci in 433,540 East Asian individuals

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  • Site-wide: 8,261
  • In genetics: 401
• Year to date:
  • Site-wide: 26,084
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  • Site-wide: 21,037

Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

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  • Site-wide: 9,419
  • In genetics: 461
• Year to date:
  • Site-wide: 65,230
• Since beginning of last month:
  • Site-wide: 63,704

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 9,448
  • In genetics: 464
• Year to date:
  • Site-wide: 80,032
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  • Site-wide: 77,425

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

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  • Site-wide: 20,279
  • In genetic and genomic medicine: 61
• Year to date:
  • Site-wide: 6,816
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  • Site-wide: 7,252

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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  • Site-wide: 27,100
  • In genetics: 1,350
• Year to date:
  • Site-wide: 26,541
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  • Site-wide: 45,487

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

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  • Site-wide: 28,780
  • In genetic and genomic medicine: 82
• Year to date:
  • Site-wide: 25,957
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  • Site-wide: 24,050

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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  • Site-wide: 29,807
  • In genomics: 2,731
• Year to date:
  • Site-wide: 72,834
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  • Site-wide: 66,779

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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  • Site-wide: 31,900
  • In genetics: 1,583
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  • Site-wide: 15,168
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  • Site-wide: 11,650

Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics

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  • Site-wide: 43,375
  • In epidemiology: 2,007
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Alcohol consumption is associated with widespread changes in blood DNA methylation: analysis of cross-sectional and longitudinal data

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  • Site-wide: 44,855
  • In epidemiology: 2,057
• Year to date:
  • Site-wide: 44,945
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  • Site-wide: 33,249

Data Resource Profile: Understanding the patterns and determinants of health in South Asians - South Asia Biobank

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  • Site-wide: 92,142
  • In epidemiology: 3,729
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  • Site-wide: 21,242
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  • Site-wide: 17,609

Low uptake of COVID-19 prevention behaviours and high socioeconomic impact of lockdown measures in South Asia: evidence from a large-scale multi-country surveillance programme

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  • Site-wide: 107,230
  • In public and global health: 1,137
• Year to date:
  • Site-wide: 30,337
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  • Site-wide: 30,934

The iHealth-T2D study: Statistical analysis plan for a cluster randomised controlled trial with intensive family based lifestyle modification programme to reduce type 2 diabetes risk amongst South Asians.

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  • Site-wide: 125,130
  • In epidemiology: 4,995
• Year to date:
  • Site-wide: 59,560
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The iHealth-T2D study: rationale and design of a cluster randomised trial for prevention of Type 2 Diabetes amongst South Asians with central obesity and prediabetes

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  • Site-wide: 126,890
  • In epidemiology: 5,083
• Year to date:
  • Site-wide: 80,982
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  • Site-wide: 60,957

Systematic Review and Scientific Rating of Commercial Apps Available in India for Diabetes Prevention

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  • Site-wide: 127,422
  • In endocrinology: 151
• Year to date:
  • Site-wide: 29,210
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  • Site-wide: 9,670