Rxivist logo

Author: Charles Kooperberg

Rankings

  • All-time downloads: 47,817 (rank: 2,929 )
  • Categories:
    • bioinformatics: 321 (rank: 30,992 (tie) )
    • epidemiology: 669 (rank: 12,020 (tie) )
    • genetic and genomic medicine: 4,973 (rank: 128 )
    • genetics: 27,612 (rank: 226 )
    • genomics: 13,188 (rank: 1,235 )
    • hematology: 467 (rank: 441 (tie) )
    • sexual and reproductive health: 587 (rank: 184 (tie) )

Downloads per author, site-wide

Preprints

Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19

infectious diseases more details view paper

No download data for this paper yet.

Recovery of trait heritability from whole genome sequence data

genetics more details view paper
  • Downloaded 11,519 times
  • Download rankings, all-time:
    • Site-wide: 657
    • In genetics: 17
  • Year to date:
    • Site-wide: 2,837
  • Since beginning of last month:
    • Site-wide: 4,537

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

genomics more details view paper
  • Downloaded 8,181 times
  • Download rankings, all-time:
    • Site-wide: 1,037
    • In genomics: 94
  • Year to date:
    • Site-wide: 2,094
  • Since beginning of last month:
    • Site-wide: 4,170

A reference panel of 64,976 haplotypes for genotype imputation

genetics more details view paper
  • Downloaded 4,585 times
  • Download rankings, all-time:
    • Site-wide: 2,235
    • In genetics: 82
  • Year to date:
    • Site-wide: 83,251
  • Since beginning of last month:
    • Site-wide: 115,200

The PAGE Study: How Genetic Diversity Improves Our Understanding of the Architecture of Complex Traits

genetics more details view paper
  • Downloaded 3,179 times
  • Download rankings, all-time:
    • Site-wide: 3,796
    • In genetics: 160
  • Year to date:
    • Site-wide: 33,182
  • Since beginning of last month:
    • Site-wide: 31,891

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

genomics more details view paper
  • Downloaded 2,882 times
  • Download rankings, all-time:
    • Site-wide: 4,335
    • In genomics: 486
  • Year to date:
    • Site-wide: 7,349
  • Since beginning of last month:
    • Site-wide: 8,717

Improving reporting standards for polygenic scores in risk prediction studies

genetic and genomic medicine more details view paper
  • Downloaded 2,111 times
  • Download rankings, all-time:
    • Site-wide: 6,857
    • In genetic and genomic medicine: 23
  • Year to date:
    • Site-wide: 2,231
  • Since beginning of last month:
    • Site-wide: 1,526

Novel genetic determinants of telomere length from a trans-ethnic analysis of 109,122 whole genome sequences in TOPMed

genetics more details view paper
  • Downloaded 1,455 times
  • Download rankings, all-time:
    • Site-wide: 11,892
    • In genetics: 580
  • Year to date:
    • Site-wide: 6,618
  • Since beginning of last month:
    • Site-wide: 4,649

Narrow-sense heritability estimation of complex traits using identity-by-descent information.

genetics more details view paper
  • Downloaded 1,138 times
  • Download rankings, all-time:
    • Site-wide: 17,261
    • In genetics: 846
  • Year to date:
    • Site-wide: 72,077
  • Since beginning of last month:
    • Site-wide: 60,000

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

genetic and genomic medicine more details view paper
  • Downloaded 1,083 times
  • Download rankings, all-time:
    • Site-wide: 18,568
    • In genetic and genomic medicine: 64
  • Year to date:
    • Site-wide: 7,302
  • Since beginning of last month:
    • Site-wide: 8,065

Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole genome sequencing studies

genetics more details view paper
  • Downloaded 839 times
  • Download rankings, all-time:
    • Site-wide: 26,822
    • In genetics: 1,303
  • Year to date:
    • Site-wide: 93,897
  • Since beginning of last month:
    • Site-wide: 100,629

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

genetics more details view paper
  • Downloaded 825 times
  • Download rankings, all-time:
    • Site-wide: 27,432
    • In genetics: 1,332
  • Year to date:
    • Site-wide: 60,293
  • Since beginning of last month:
    • Site-wide: 63,983

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

genomics more details view paper
  • Downloaded 742 times
  • Download rankings, all-time:
    • Site-wide: 31,829
    • In genomics: 2,834
  • Year to date:
    • Site-wide: 79,956
  • Since beginning of last month:
    • Site-wide: 113,266

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

genetics more details view paper
  • Downloaded 713 times
  • Download rankings, all-time:
    • Site-wide: 33,588
    • In genetics: 1,633
  • Year to date:
    • Site-wide: 120,770
  • Since beginning of last month:
    • Site-wide: 108,350

Integration of rare large-effect expression variants improves polygenic risk prediction

genetic and genomic medicine more details view paper
  • Downloaded 685 times
  • Download rankings, all-time:
    • Site-wide: 35,485
    • In genetic and genomic medicine: 112
  • Year to date:
    • Site-wide: 6,975
  • Since beginning of last month:
    • Site-wide: 13,503

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

genomics more details view paper
  • Downloaded 667 times
  • Download rankings, all-time:
    • Site-wide: 36,809
    • In genomics: 3,140
  • Year to date:
    • Site-wide: 73,370
  • Since beginning of last month:
    • Site-wide: 96,742

Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

genetics more details view paper
  • Downloaded 617 times
  • Download rankings, all-time:
    • Site-wide: 40,700
    • In genetics: 1,939
  • Year to date:
    • Site-wide: 4,755
  • Since beginning of last month:
    • Site-wide: 13,485

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

genetics more details view paper
  • Downloaded 613 times
  • Download rankings, all-time:
    • Site-wide: 41,051
    • In genetics: 1,950
  • Year to date:
    • Site-wide: 74,782
  • Since beginning of last month:
    • Site-wide: 63,928

Genetic insights into the biological mechanisms governing human ovarian ageing

sexual and reproductive health more details view paper
  • Downloaded 587 times
  • Download rankings, all-time:
    • Site-wide: 43,368
    • In sexual and reproductive health: 18
  • Year to date:
    • Site-wide: 2,236
  • Since beginning of last month:
    • Site-wide: 6,209

Exome chip meta-analysis elucidates the genetic architecture of rare coding variants in smoking and drinking behavior

genetics more details view paper
  • Downloaded 577 times
  • Download rankings, all-time:
    • Site-wide: 44,223
    • In genetics: 2,081
  • Year to date:
    • Site-wide: 113,818
  • Since beginning of last month:
    • Site-wide: 89,094

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

genomics more details view paper
  • Downloaded 506 times
  • Download rankings, all-time:
    • Site-wide: 51,862
    • In genomics: 4,019
  • Year to date:
    • Site-wide: 119,396
  • Since beginning of last month:
    • Site-wide: 115,463

Whole genome sequencing association analysis of quantitative red blood cell phenotypes: the NHLBI TOPMed program

hematology more details view paper
  • Downloaded 467 times
  • Download rankings, all-time:
    • Site-wide: 56,769
    • In hematology: 34
  • Year to date:
    • Site-wide: 6,196
  • Since beginning of last month:
    • Site-wide: 10,720

Threshold trait architecture of Hsp90-buffered variation

genetics more details view paper
  • Downloaded 418 times
  • Download rankings, all-time:
    • Site-wide: 63,662
    • In genetics: 2,958
  • Year to date:
    • Site-wide: 127,704
  • Since beginning of last month:
    • Site-wide: 132,468

Impact of rare and common genetic variants on diabetes diagnosis by hemoglobin A1c in multi-ancestry cohorts: The Trans-Omics for Precision Medicine Program.

genetics more details view paper
  • Downloaded 396 times
  • Download rankings, all-time:
    • Site-wide: 67,027
    • In genetics: 3,092
  • Year to date:
    • Site-wide: 59,767
  • Since beginning of last month:
    • Site-wide: 63,152

Multi-ethnic genome-wide association study of decomposed cardioelectric phenotypes illustrates strategies to identify and characterize evidence of shared genetic effects for complex traits

epidemiology more details view paper
  • Downloaded 368 times
  • Download rankings, all-time:
    • Site-wide: 71,805
    • In epidemiology: 3,019
  • Year to date:
    • Site-wide: 85,526
  • Since beginning of last month:
    • Site-wide: 63,290

Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries

bioinformatics more details view paper
  • Downloaded 321 times
  • Download rankings, all-time:
    • Site-wide: 80,575
    • In bioinformatics: 7,376
  • Year to date:
    • Site-wide: 54,011
  • Since beginning of last month:
    • Site-wide: 36,394

Rare Non-coding Variation Identified by Large Scale Whole Genome Sequencing Reveals Unexplained Heritability of Type 2 Diabetes: Trans-Omics for Precision Medicine (TOPMed) Program

genetic and genomic medicine more details view paper
  • Downloaded 320 times
  • Download rankings, all-time:
    • Site-wide: 80,812
    • In genetic and genomic medicine: 285
  • Year to date:
    • Site-wide: 22,574
  • Since beginning of last month:
    • Site-wide: 18,869

Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

epidemiology more details view paper
  • Downloaded 301 times
  • Download rankings, all-time:
    • Site-wide: 84,688
    • In epidemiology: 3,488
  • Year to date:
    • Site-wide: 74,117
  • Since beginning of last month:
    • Site-wide: 73,457

A system for phenotype harmonization in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program

genetics more details view paper
  • Downloaded 292 times
  • Download rankings, all-time:
    • Site-wide: 86,444
    • In genetics: 3,914
  • Year to date:
    • Site-wide: 47,301
  • Since beginning of last month:
    • Site-wide: None

GWAS of QRS Duration Identifies New Loci Specific to Hispanic/Latino Populations

genetics more details view paper
  • Downloaded 259 times
  • Download rankings, all-time:
    • Site-wide: 93,759
    • In genetics: 4,207
  • Year to date:
    • Site-wide: 128,857
  • Since beginning of last month:
    • Site-wide: 121,210

Genetic architectures of proximal and distal colorectal cancer are partly distinct

genetic and genomic medicine more details view paper
  • Downloaded 242 times
  • Download rankings, all-time:
    • Site-wide: 97,244
    • In genetic and genomic medicine: 381
  • Year to date:
    • Site-wide: 57,819
  • Since beginning of last month:
    • Site-wide: 57,029

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

genomics more details view paper
  • Downloaded 210 times
  • Download rankings, all-time:
    • Site-wide: 104,532
    • In genomics: 6,116
  • Year to date:
    • Site-wide: 96,193
  • Since beginning of last month:
    • Site-wide: 67,360

A large-scale transcriptome-wide association study (TWAS) of ten blood cell phenotypes reveals complexities of TWAS fine-mapping

genetics more details view paper
  • Downloaded 187 times
  • Download rankings, all-time:
    • Site-wide: 109,463
    • In genetics: 4,785
  • Year to date:
    • Site-wide: 11,273
  • Since beginning of last month:
    • Site-wide: 9,738

Bidirectional Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of intermediate potential

genetic and genomic medicine more details view paper
  • Downloaded 183 times
  • Download rankings, all-time:
    • Site-wide: 110,332
    • In genetic and genomic medicine: 484
  • Year to date:
    • Site-wide: 11,626
  • Since beginning of last month:
    • Site-wide: 3,006

Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program

genetic and genomic medicine more details view paper
  • Downloaded 178 times
  • Download rankings, all-time:
    • Site-wide: 111,392
    • In genetic and genomic medicine: 495
  • Year to date:
    • Site-wide: 12,001
  • Since beginning of last month:
    • Site-wide: 33,227

BinomiRare: A carriers-only test for association of rare genetic variants with a binary outcome for mixed models and any case-control proportion

genetic and genomic medicine more details view paper
  • Downloaded 171 times
  • Download rankings, all-time:
    • Site-wide: 112,894
    • In genetic and genomic medicine: 511
  • Year to date:
    • Site-wide: 12,671
  • Since beginning of last month:
    • Site-wide: 37,186

PanLingua

Sign up for the Rxivist weekly newsletter! (Click here for more details.)


News