Author: Howard J. Edenberg

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Preprints

Genomewide association study identifies 30 loci associated with bipolar disorder

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  • Site-wide: 1,132
  • In genetics: 38
• Year to date:
  • Site-wide: 16,215
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  • Site-wide: 13,472

Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

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  • Site-wide: 2,029
  • In genomics: 216
• Year to date:
  • Site-wide: 12,884
• Since beginning of last month:
  • Site-wide: 15,509

Psychiatric Genomics: An Update and an Agenda

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  • Site-wide: 3,319
  • In genetics: 134
• Year to date:
  • Site-wide: 60,957
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  • Site-wide: 64,222

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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  • Site-wide: 7,716
  • In genetics: 369
• Year to date:
  • Site-wide: 63,060
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  • Site-wide: 63,332

Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts (N=141,932)

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  • Site-wide: 9,051
  • In genetics: 447
• Year to date:
  • Site-wide: 44,826
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  • Site-wide: 33,685

Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights

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  • Site-wide: 10,156
  • In psychiatry and clinical psychology: 32
• Year to date:
  • Site-wide: 2,715
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  • Site-wide: 3,306

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

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  • Site-wide: 13,391
  • In genetics: 675
• Year to date:
  • Site-wide: 73,426
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  • Site-wide: 63,735

Meta-analysis of problematic alcohol use in 435,563 individuals identifies 29 risk variants and yields insights into biology, pleiotropy and causality

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  • Site-wide: 18,041
  • In genetics: 904
• Year to date:
  • Site-wide: 26,254
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  • Site-wide: 23,711

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

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  • Site-wide: 30,568
  • In genetics: 1,517
• Year to date:
  • Site-wide: 18,893
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  • Site-wide: 10,448

Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

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  • Site-wide: 31,881
  • In genetics: 1,585
• Year to date:
  • Site-wide: 106,375
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Genetic Data Can Lead to Medical Discrimination: Opioid Use Disorder as a Cautionary Tale

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  • Site-wide: 32,130
  • In addiction medicine: 6
• Year to date:
  • Site-wide: 6,991
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  • Site-wide: 11,638

Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

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  • Site-wide: 33,766
  • In genetics: 1,659
• Year to date:
  • Site-wide: 20,314
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  • Site-wide: 40,643

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

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  • Site-wide: 37,220
  • In genetics: 1,813
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  • Site-wide: 14,841
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  • Site-wide: 6,026

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

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  • Site-wide: 60,846
  • In genetic and genomic medicine: 182
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  • Site-wide: 10,537
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  • Site-wide: 16,018

Multivariate GWAS elucidates the genetic architecture of alcohol consumption and misuse, corrects biases, and reveals novel associations with disease

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  • Site-wide: 69,331
  • In genetics: 3,236
• Year to date:
  • Site-wide: 26,755
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  • Site-wide: 20,398

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

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  • Site-wide: 77,729
  • In neuroscience: 11,984
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Polygenic Prediction of Substance Use Disorders in Clinical and Population Samples

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  • Site-wide: 79,683
  • In genetics: 3,691
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  • Site-wide: 72,343
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  • Site-wide: 52,219

Allele-Specific Expression and High-Throughput Reporter Assay Reveal Functional Variants in Human Brains with Alcohol Use Disorders

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  • Site-wide: 88,575
  • In neuroscience: 13,790
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Multi-omics integration analysis identifies novel genes for alcoholism with potential link to neurodegenerative diseases

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  • Site-wide: 94,264
  • In genomics: 5,790
• Year to date:
  • Site-wide: 26,484
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  • Site-wide: 35,816

Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder

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  • Site-wide: 102,267
  • In genetic and genomic medicine: 396
• Year to date:
  • Site-wide: 52,229
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  • Site-wide: 48,949

The Addiction Genetic Factor a(g): A Unitary Genetic Vulnerability Characterizes Substance Use Disorders and Their Associations with Common Correlates

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  • Site-wide: 102,535
  • In addiction medicine: 46
• Year to date:
  • Site-wide: 4,782
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  • Site-wide: 3,430