Author: Nancy L. Pedersen

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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  • Site-wide: 818
  • In genetics: 25
• Year to date:
  • Site-wide: 23,006
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  • Site-wide: 25,260

Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimers disease risk

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  • Site-wide: 1,766
  • In genetics: 66
• Year to date:
  • Site-wide: 23,677
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  • Site-wide: 28,603

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

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  • Site-wide: 1,791
  • In genetics: 68
• Year to date:
  • Site-wide: 26,038
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  • Site-wide: None

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

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  • Site-wide: 3,468
  • In genetics: 149
• Year to date:
  • Site-wide: 25,947
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  • Site-wide: 25,762

Common variants in Alzheimer's disease: Novel association of six genetic variants with AD and risk stratification by polygenic risk scores

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  • Site-wide: 5,527
  • In genetic and genomic medicine: 15
• Year to date:
  • Site-wide: 9,168
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  • Site-wide: 10,320

Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

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  • Site-wide: 6,406
  • In genetics: 319
• Year to date:
  • Site-wide: 18,171
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  • Site-wide: 15,160

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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  • Site-wide: 7,712
  • In genetics: 369
• Year to date:
  • Site-wide: 62,350
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  • Site-wide: 64,490

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

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  • Site-wide: 8,888
  • In genetics: 440
• Year to date:
  • Site-wide: 56,079
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  • Site-wide: 54,444

Largest GWAS (N=1,126,563) of Alzheimer's Disease Implicates Microglia and Immune Cells

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  • Site-wide: 9,146
  • In genetic and genomic medicine: 26
• Year to date:
  • Site-wide: 2,299
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  • Site-wide: 2,050

A Genome-Wide Association Study of the Frailty Index Highlights Synaptic Pathways in Aging

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  • Site-wide: 12,001
  • In genetic and genomic medicine: 41
• Year to date:
  • Site-wide: 38,865
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  • Site-wide: 27,480

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

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  • Site-wide: 19,002
  • In genetics: 944
• Year to date:
  • Site-wide: 6,496
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  • Site-wide: 6,589

An epigenome-wide association study of educational attainment (n = 10,767)

• Downloaded 984 times
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  • Site-wide: 20,143
  • In genetics: 1,000
• Year to date:
  • Site-wide: 47,231
• Since beginning of last month:
  • Site-wide: 42,900

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

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  • Site-wide: 26,412
  • In genetics: 1,315
• Year to date:
  • Site-wide: 47,028
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  • Site-wide: 64,714

Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness

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  • Site-wide: 27,336
  • In genetics: 1,360
• Year to date:
  • Site-wide: 112,853
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  • Site-wide: 80,907

Profiles of circulating histidine-rich glycoprotein associate with chronological age and risk of all-cause mortality

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  • Site-wide: 33,294
  • In epidemiology: 1,631
• Year to date:
  • Site-wide: 73,201
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  • Site-wide: None

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

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  • Site-wide: 35,289
  • In genetics: 1,729
• Year to date:
  • Site-wide: 111,282
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  • Site-wide: 78,589

A frailty index for UK Biobank participants

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  • Site-wide: 35,929
  • In epidemiology: 1,722
• Year to date:
  • Site-wide: 83,111
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  • Site-wide: 81,356

Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

• Downloaded 633 times
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  • Site-wide: 37,197
  • In genetics: 1,813
• Year to date:
  • Site-wide: 14,693
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  • Site-wide: 5,861

The Anorexia Nervosa Genetics Initiative: Overview and Methods

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  • Site-wide: 37,951
  • In genetics: 1,851
• Year to date:
  • Site-wide: 84,560
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  • Site-wide: 54,661

A decade of epigenetic change in aging twins: genetic and environmental contributions to longitudinal DNA methylation

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  • Site-wide: 43,954
  • In genetics: 2,115
• Year to date:
  • Site-wide: 56,995
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  • Site-wide: None

Genetic insights into the biological mechanisms governing human ovarian ageing

• Downloaded 470 times
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  • Site-wide: 53,356
  • In sexual and reproductive health: 20
• Year to date:
  • Site-wide: 1,386
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  • Site-wide: 1,563

Genetic variation in the Major Histocompatibility Complex and association with depression

• Downloaded 420 times
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  • Site-wide: 60,016
  • In genetics: 2,840
• Year to date:
  • Site-wide: 114,613
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  • Site-wide: 81,663

Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer's disease

• Downloaded 399 times
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  • Site-wide: 63,168
  • In genomics: 4,590
• Year to date:
  • Site-wide: 102,882
• Since beginning of last month:
  • Site-wide: 95,128

Drivers of Frailty from Adulthood into Old Age: Results from a 27-year Longitudinal Population-Based Study in Sweden

• Downloaded 327 times
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  • Site-wide: 75,365
  • In epidemiology: 3,107
• Year to date:
  • Site-wide: 69,163
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  • Site-wide: 57,430

Asthma and affective traits in adults: a genetically informative study

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  • Site-wide: 86,700
  • In genetics: 3,979
• Year to date:
  • Site-wide: 108,619
• Since beginning of last month:
  • Site-wide: 100,558

Comprehensive longitudinal study of epigenetic mutations in aging

• Downloaded 250 times
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  • Site-wide: 91,112
  • In genetics: 4,152
• Year to date:
  • Site-wide: 90,325
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  • Site-wide: 64,854

DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

• Downloaded 247 times
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  • Site-wide: 91,722
  • In genetics: 4,183
• Year to date:
  • Site-wide: 39,494
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  • Site-wide: 34,361

Neuroticism as a predictor of frailty in old age: a genetically informative approach

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  • Site-wide: 93,732
  • In epidemiology: 3,793
• Year to date:
  • Site-wide: 49,253
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  • Site-wide: 37,501

The frailty index is a predictor of cause-specific mortality independent of familial effects from midlife onwards

• Downloaded 215 times
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  • Site-wide: 98,635
  • In epidemiology: 4,007
• Year to date:
  • Site-wide: 114,510
• Since beginning of last month:
  • Site-wide: 95,769

Sex differences in genetic and environmental influences on frailty and its relation to body mass index and education

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  • Site-wide: 112,890
  • In geriatric medicine: 61
• Year to date:
  • Site-wide: 16,393
• Since beginning of last month:
  • Site-wide: 15,597

The genetic architecture of obsessive-compulsive disorder: alleles across the frequency spectrum contribute liability to OCD

• Downloaded 95 times
• Download rankings, all-time:
  • Site-wide: 121,957
  • In psychiatry and clinical psychology: 571
• Year to date:
  • Site-wide: 12,427
• Since beginning of last month:
  • Site-wide: 9,311