Author: Jian’an Luan

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Preprints

Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes

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  • Site-wide: 5,365
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• Year to date:
  • Site-wide: 2,827
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  • Site-wide: 4,461

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 8,945
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• Year to date:
  • Site-wide: 64,151
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  • Site-wide: 38,011

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

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  • Site-wide: 9,570
  • In genomics: 1,084
• Year to date:
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  • Site-wide: 45,847

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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  • Site-wide: 10,511
  • In genetics: 532
• Year to date:
  • Site-wide: 39,282
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  • Site-wide: 68,105

Genetic architecture of host proteins interacting with SARS-CoV-2

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  • Site-wide: 11,232
  • In genomics: 1,275
• Year to date:
  • Site-wide: 4,655
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  • Site-wide: 3,801

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

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  • Site-wide: 11,276
  • In genetics: 573
• Year to date:
  • Site-wide: 76,525
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  • Site-wide: 62,001

A Comprehensive Reanalysis Of Publicly Available GWAS Datasets Reveals An X Chromosome Rare Regulatory Variant Associated With High Risk For Type 2 Diabetes.

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  • Site-wide: 12,579
  • In genetics: 646
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  • Site-wide: 66,945
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  • Site-wide: 80,179

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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  • Site-wide: 27,227
  • In genetics: 1,372
• Year to date:
  • Site-wide: 21,330
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  • Site-wide: 24,317

Genome-wide scan and fine-mapping of rare nonsynonymous associations implicates intracellular lipolysis genes in fat distribution and cardio-metabolic risk

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  • Site-wide: 32,995
  • In genetics: 1,650
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  • Site-wide: 44,496
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  • Site-wide: 40,766

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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  • Site-wide: 34,277
  • In genetics: 1,717
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  • Site-wide: 20,702
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  • Site-wide: 11,192

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

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  • Site-wide: 42,551
  • In genetics: 2,090
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  • Site-wide: 76,042
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  • Site-wide: 79,040

Regional fat depot masses are influenced by protein-coding gene variants

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  • Site-wide: 91,631
  • In genomics: 5,661
• Year to date:
  • Site-wide: 102,285
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  • Site-wide: 93,905