Author: Najaf Amin

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Preprints

New insights on the genetic etiology of Alzheimer and related dementia

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  • Site-wide: 3,445
  • In neurology: 9
• Year to date:
  • Site-wide: 578
• Since beginning of last month:
  • Site-wide: 423

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

• Downloaded 3,261 times
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  • Site-wide: 3,657
  • In genetics: 150
• Year to date:
  • Site-wide: 38,989
• Since beginning of last month:
  • Site-wide: 79,985

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

• Downloaded 3,082 times
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  • Site-wide: 3,953
  • In genetics: 168
• Year to date:
  • Site-wide: 52,683
• Since beginning of last month:
  • Site-wide: 66,453

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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  • Site-wide: 8,334
  • In genetics: 391
• Year to date:
  • Site-wide: 85,043
• Since beginning of last month:
  • Site-wide: 81,681

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

• Downloaded 1,717 times
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  • Site-wide: 9,354
  • In genetics: 447
• Year to date:
  • Site-wide: 79,904
• Since beginning of last month:
  • Site-wide: 81,699

Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

• Downloaded 1,442 times
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  • Site-wide: 12,041
  • In genetics: 589
• Year to date:
  • Site-wide: 29,303
• Since beginning of last month:
  • Site-wide: 22,967

Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour

• Downloaded 1,282 times
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  • Site-wide: 14,434
  • In genetics: 715
• Year to date:
  • Site-wide: 80,436
• Since beginning of last month:
  • Site-wide: 81,665

Exome sequencing identifies novel AD-associated genes.

• Downloaded 1,084 times
• Download rankings, all-time:
  • Site-wide: 18,524
  • In genetic and genomic medicine: 63
• Year to date:
  • Site-wide: 10,180
• Since beginning of last month:
  • Site-wide: 11,479

Genetic Association Study of Childhood Aggression across raters, instruments and age

• Downloaded 898 times
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  • Site-wide: 24,351
  • In genomics: 2,333
• Year to date:
  • Site-wide: 16,233
• Since beginning of last month:
  • Site-wide: 9,363

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

• Downloaded 840 times
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  • Site-wide: 26,731
  • In genetics: 1,300
• Year to date:
  • Site-wide: 27,088
• Since beginning of last month:
  • Site-wide: 19,389

Quality Control and Integration of Genotypes from Two Calling Pipelines for Whole Genome Sequence Data in the Alzheimer's Disease Sequencing Project

• Downloaded 819 times
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  • Site-wide: 27,719
  • In genetics: 1,352
• Year to date:
  • Site-wide: 42,582
• Since beginning of last month:
  • Site-wide: 66,400

Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness

• Downloaded 801 times
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  • Site-wide: 28,574
  • In genetics: 1,385
• Year to date:
  • Site-wide: 112,642
• Since beginning of last month:
  • Site-wide: 91,419

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

• Downloaded 794 times
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  • Site-wide: 28,939
  • In genetics: 1,404
• Year to date:
  • Site-wide: 13,195
• Since beginning of last month:
  • Site-wide: 8,904

Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants

• Downloaded 784 times
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  • Site-wide: 29,435
  • In genetics: 1,428
• Year to date:
  • Site-wide: 19,635
• Since beginning of last month:
  • Site-wide: 19,631

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

• Downloaded 751 times
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  • Site-wide: 31,271
  • In genomics: 2,798
• Year to date:
  • Site-wide: 92,614
• Since beginning of last month:
  • Site-wide: 103,016

Genome-wide association study of plasma triglycerides, phospholipids and relation to cardio-metabolic risk factors

• Downloaded 722 times
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  • Site-wide: 33,065
  • In epidemiology: 1,650
• Year to date:
  • Site-wide: 45,000
• Since beginning of last month:
  • Site-wide: 37,919

Relationship between gut microbiota and circulating metabolites in population-based cohorts

• Downloaded 692 times
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  • Site-wide: 35,031
  • In epidemiology: 1,720
• Year to date:
  • Site-wide: 127,876
• Since beginning of last month:
  • Site-wide: 128,635

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

• Downloaded 506 times
• Download rankings, all-time:
  • Site-wide: 51,792
  • In genomics: 4,020
• Year to date:
  • Site-wide: 119,149
• Since beginning of last month:
  • Site-wide: 119,940

Common genetic variation indicates separate etiologies for periventricular and deep white matter hyperintensities

• Downloaded 439 times
• Download rankings, all-time:
  • Site-wide: 60,460
  • In neuroscience: 9,091
• Year to date:
  • Site-wide: 94,216
• Since beginning of last month:
  • Site-wide: 93,729

Novel DNA methylation sites of glucose and insulin homeostasis: an integrative cross-omics analysis

• Downloaded 352 times
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  • Site-wide: 74,614
  • In genomics: 5,060
• Year to date:
  • Site-wide: 126,048
• Since beginning of last month:
  • Site-wide: 122,833

Effect of inbreeding on type 2 diabetes-related metabolites in a Dutch genetic isolate

• Downloaded 254 times
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  • Site-wide: 94,688
  • In genetics: 4,254
• Year to date:
  • Site-wide: 127,764
• Since beginning of last month:
  • Site-wide: 125,552

Recessive genetic effects on type 2 diabetes-related metabolites in a consanguineous population

• Downloaded 223 times
• Download rankings, all-time:
  • Site-wide: 101,546
  • In genetics: 4,515
• Year to date:
  • Site-wide: 132,965
• Since beginning of last month:
  • Site-wide: 128,653

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

• Downloaded 210 times
• Download rankings, all-time:
  • Site-wide: 104,515
  • In genomics: 6,111
• Year to date:
  • Site-wide: 96,101
• Since beginning of last month:
  • Site-wide: 69,196