Author: Tim D Spector

Downloads per author, site-wide

Preprints

The Genomic Loci of Specific Human tRNA Genes Exhibit Ageing-Related DNA Hypermethylation

No bioRxiv download data for this paper yet.

Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use

• Downloaded 8,383 times
• Download rankings, all-time:
  • Site-wide: 297 out of 84,901
  • In genetics: 23 out of 4,454
• Year to date:
  • Site-wide: 15,728 out of 84,901
• Since beginning of last month:
  • Site-wide: 22,918 out of 84,901

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

• Downloaded 2,906 times
• Download rankings, all-time:
  • Site-wide: 1,826 out of 84,901
  • In genetics: 147 out of 4,454
• Year to date:
  • Site-wide: 24,176 out of 84,901
• Since beginning of last month:
  • Site-wide: 20,274 out of 84,901

Interplay between the human gut microbiome and host metabolism

• Downloaded 2,058 times
• Download rankings, all-time:
  • Site-wide: 3,275 out of 84,901
  • In microbiology: 196 out of 7,209
• Year to date:
  • Site-wide: 9,868 out of 84,901
• Since beginning of last month:
  • Site-wide: 24,167 out of 84,901

Genome-wide association study identifies 48 common genetic variants associated with handedness

• Downloaded 1,989 times
• Download rankings, all-time:
  • Site-wide: 3,456 out of 84,901
  • In genetics: 267 out of 4,454
• Year to date:
  • Site-wide: 7,432 out of 84,901
• Since beginning of last month:
  • Site-wide: 13,654 out of 84,901

The genetics of the human face: identification of large effect single gene variants

• Downloaded 1,682 times
• Download rankings, all-time:
  • Site-wide: 4,564 out of 84,901
  • In genetics: 343 out of 4,454
• Year to date:
  • Site-wide: 26,305 out of 84,901
• Since beginning of last month:
  • Site-wide: 13,348 out of 84,901

Genetic Associations with Subjective Well-Being Also Implicate Depression and Neuroticism

• Downloaded 1,602 times
• Download rankings, all-time:
  • Site-wide: 4,955 out of 84,901
  • In genetics: 378 out of 4,454
• Year to date:
  • Site-wide: 46,334 out of 84,901
• Since beginning of last month:
  • Site-wide: 36,400 out of 84,901

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

• Downloaded 1,346 times
• Download rankings, all-time:
  • Site-wide: 6,637 out of 84,901
  • In genetics: 482 out of 4,454
• Year to date:
  • Site-wide: 23,069 out of 84,901
• Since beginning of last month:
  • Site-wide: 48,186 out of 84,901

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

• Downloaded 1,156 times
• Download rankings, all-time:
  • Site-wide: 8,538 out of 84,901
  • In genomics: 1,286 out of 5,475
• Year to date:
  • Site-wide: 71,800 out of 84,901
• Since beginning of last month:
  • Site-wide: 62,324 out of 84,901

Genome-wide association study of offspring birth weight in 86,577 women highlights maternal genetic effects that are independent of fetal genetics

• Downloaded 1,112 times
• Download rankings, all-time:
  • Site-wide: 9,106 out of 84,901
  • In genetics: 648 out of 4,454
• Year to date:
  • Site-wide: 53,946 out of 84,901
• Since beginning of last month:
  • Site-wide: 36,001 out of 84,901

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

• Downloaded 1,039 times
• Download rankings, all-time:
  • Site-wide: 10,158 out of 84,901
  • In genetics: 697 out of 4,454
• Year to date:
  • Site-wide: 31,654 out of 84,901
• Since beginning of last month:
  • Site-wide: 25,184 out of 84,901

Profound perturbation of the human metabolome by obesity

• Downloaded 807 times
• Download rankings, all-time:
  • Site-wide: 15,080 out of 84,901
  • In genetics: 981 out of 4,454
• Year to date:
  • Site-wide: 58,295 out of 84,901
• Since beginning of last month:
  • Site-wide: 44,575 out of 84,901

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

• Downloaded 683 times
• Download rankings, all-time:
  • Site-wide: 19,352 out of 84,901
  • In genomics: 2,301 out of 5,475
• Year to date:
  • Site-wide: 48,362 out of 84,901
• Since beginning of last month:
  • Site-wide: 65,400 out of 84,901

Network-based metabolite ratios for an improved functional characterization of genome-wide association study results

• Downloaded 551 times
• Download rankings, all-time:
  • Site-wide: 26,177 out of 84,901
  • In genetics: 1,631 out of 4,454
• Year to date:
  • Site-wide: 65,035 out of 84,901
• Since beginning of last month:
  • Site-wide: 72,380 out of 84,901

Decreased IgG core fucosylation, a player in antibody-dependent cell-mediated cytotoxicity, is associated with autoimmune thyroid diseases

• Downloaded 451 times
• Download rankings, all-time:
  • Site-wide: 33,462 out of 84,901
  • In immunology: 790 out of 2,384
• Year to date:
  • Site-wide: 57,618 out of 84,901
• Since beginning of last month:
  • Site-wide: 31,256 out of 84,901

Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health

• Downloaded 415 times
• Download rankings, all-time:
  • Site-wide: 36,759 out of 84,901
  • In genomics: 3,495 out of 5,475
• Year to date:
  • Site-wide: 74,540 out of 84,901
• Since beginning of last month:
  • Site-wide: 75,543 out of 84,901

Novel DNA methylation sites of glucose and insulin homeostasis: an integrative cross-omics analysis

• Downloaded 307 times
• Download rankings, all-time:
  • Site-wide: 49,344 out of 84,901
  • In genomics: 4,134 out of 5,475
• Year to date:
  • Site-wide: 66,030 out of 84,901
• Since beginning of last month:
  • Site-wide: 44,164 out of 84,901

Multi-omic analyses reveal antibody-dependent natural killer cell-mediated cytotoxicity in autoimmune thyroid diseases

• Downloaded 289 times
• Download rankings, all-time:
  • Site-wide: 51,843 out of 84,901
  • In immunology: 1,296 out of 2,384
• Year to date:
  • Site-wide: 37,627 out of 84,901
• Since beginning of last month:
  • Site-wide: 23,429 out of 84,901

KCND3 is a novel susceptibility locus for early repolarization

• Downloaded 191 times
• Download rankings, all-time:
  • Site-wide: 67,367 out of 84,901
  • In genetics: 3,704 out of 4,454
• Year to date:
  • Site-wide: 75,795 out of 84,901
• Since beginning of last month:
  • Site-wide: 50,508 out of 84,901

Introducing ExHiBITT – Exploring Host microbiome inTeractions in Twins-, a colon multiomic cohort study

• Downloaded 150 times
• Download rankings, all-time:
  • Site-wide: 73,883 out of 84,901
  • In systems biology: 2,061 out of 2,235
• Year to date:
  • Site-wide: 52,660 out of 84,901
• Since beginning of last month:
  • Site-wide: 51,853 out of 84,901