Author: Benjamin G Neel

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Preprints

Both Fallopian Tube and Ovarian Surface Epithelium Can Act as Cell-of-Origin for High Grade Serous Ovarian Carcinoma

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  • Site-wide: 8,428
  • In cancer biology: 153
• Year to date:
  • Site-wide: 62,423
• Since beginning of last month:
  • Site-wide: 59,319

SHP2 Inhibition Abrogates MEK inhibitor Resistance in Multiple Cancer Models

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  • Site-wide: 9,990
  • In cancer biology: 198
• Year to date:
  • Site-wide: 28,427
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  • Site-wide: 46,134

Distinct cancer-associated fibroblast states drive clinical outcomes in high-grade serous ovarian cancer and are regulated by TCF21

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  • Site-wide: 12,831
  • In cancer biology: 277
• Year to date:
  • Site-wide: 38,824
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  • Site-wide: 20,879

SHP2 Inhibition Abrogates Adaptive Resistance to KRASG12C-Inhibition and Remodels the Tumor Microenvironment of KRAS-Mutant Tumors

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  • Site-wide: 14,126
  • In cancer biology: 303
• Year to date:
  • Site-wide: 9,513
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  • Site-wide: 4,664

Off-target inhibition by active site-targeting SHP2 inhibitors

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  • Site-wide: 15,913
  • In cell biology: 511
• Year to date:
  • Site-wide: 22,094
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  • Site-wide: 38,313

Genetically Defined, Syngeneic Organoid Platform for Developing Combination Therapies for Ovarian Cancer

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  • Site-wide: 19,633
  • In cancer biology: 470
• Year to date:
  • Site-wide: 23,730
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  • Site-wide: 30,029

SHP2 Is Required for BCR-ABL1-Induced Hematologic Neoplasms

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  • Site-wide: 41,533
  • In cancer biology: 1,155
• Year to date:
  • Site-wide: 103,066
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  • Site-wide: 83,973

Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival

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  • Site-wide: 51,151
  • In bioinformatics: 5,325
• Year to date:
  • Site-wide: 99,494
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  • Site-wide: 116,817

Assay to visualize specific protein oxidation reveals spatio-temporal regulation of SHP2

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  • Site-wide: 51,650
  • In cell biology: 2,257
• Year to date:
  • Site-wide: 115,646
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  • Site-wide: 114,864

Cellular Interplay and Cytokine Hierarchy Cause Pathological Cardiac Hypertrophy in RAF1-Mutant Noonan Syndrome

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  • Site-wide: 57,937
  • In cell biology: 2,567
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  • Site-wide: 111,326
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  • Site-wide: 91,563

Activated thiol Sepharose-based proteomic approach to globally quantify protein oxidation

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  • Site-wide: 61,567
  • In biochemistry: 1,658
• Year to date:
  • Site-wide: 71,478
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  • Site-wide: 52,703

Computational Modeling of Ovarian Cancer: Implications for Therapy and Screening

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  • Site-wide: 67,090
  • In oncology: 76
• Year to date:
  • Site-wide: 33,179
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  • Site-wide: 44,734

Moyamoya Disease-Associated RNF213 Alleles Encode Dominant Negative Alleles That Globally Impair Ubiquitylation

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  • Site-wide: 69,114
  • In biochemistry: 1,888
• Year to date:
  • Site-wide: 104,173
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  • Site-wide: 48,159

Ontogeny and Vulnerabilities of Lapatinib Drug-Tolerant Persisters in HER2+ Breast Cancer

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  • Site-wide: 76,598
  • In cancer biology: 2,259
• Year to date:
  • Site-wide: 14,141
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  • Site-wide: 15,878

Pathological Oxidation of PTPN12 Underlies ABL1 Phosphorylation in HLRCC

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  • Site-wide: 83,039
  • In cancer biology: 2,483
• Year to date:
  • Site-wide: 77,878
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  • Site-wide: 101,903