Author: Scott E Hensley

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Preprints

mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern

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  • In immunology: 13
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  • Site-wide: 285
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  • Site-wide: 170

Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions

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  • Site-wide: 900
  • In immunology: 40
• Year to date:
  • Site-wide: 10,465
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  • Site-wide: 7,264

Antigenic and virological properties of an H3N2 variant that will likely dominate the 2021-2022 Northern Hemisphere influenza season

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  • Site-wide: 1,268
  • In infectious diseases: 535
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  • Site-wide: 203
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Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection

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  • Site-wide: 2,275
  • In immunology: 85
• Year to date:
  • Site-wide: 13,474
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  • Site-wide: 13,677

Rapid induction of antigen-specific CD4+ T cells guides coordinated humoral and cellular immune responses to SARS-CoV-2 mRNA vaccination

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  • Site-wide: 2,972
  • In immunology: 116
• Year to date:
  • Site-wide: 8,860
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  • Site-wide: 8,654

SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared to SARS-CoV-2 mRNA vaccinations

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  • Site-wide: 4,155
  • In infectious diseases: 915
• Year to date:
  • Site-wide: 6,985
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  • Site-wide: 28,914

Longitudinal Analysis Reveals Distinct Antibody and Memory B Cell Responses in SARS-CoV2 Naive and Recovered Individuals Following mRNA Vaccination

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  • Site-wide: 5,563
  • In infectious diseases: 1,123
• Year to date:
  • Site-wide: 8,312
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  • Site-wide: 8,187

Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection

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  • Site-wide: 7,229
  • In infectious diseases: 1,282
• Year to date:
  • Site-wide: 28,271
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  • Site-wide: 22,480

Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine

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  • Site-wide: 8,872
  • In immunology: 519
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  • Site-wide: 488
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  • Site-wide: 3,712

Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals

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  • In allergy and immunology: 58
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  • Site-wide: 4,999
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  • Site-wide: 16,781

SARS-CoV-2 seropositivity and seroconversion in patients undergoing active cancer-directed therapy

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  • Site-wide: 12,311
  • In oncology: 15
• Year to date:
  • Site-wide: 44,593
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  • Site-wide: 46,203

Altered cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy.

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  • Site-wide: 14,924
  • In neurology: 37
• Year to date:
  • Site-wide: 41,042
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  • Site-wide: 55,876

Sero-monitoring of health care workers reveals complex relationships between common coronavirus antibodies and SARS-CoV-2 severity

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  • Site-wide: 16,868
  • In infectious diseases: 2,041
• Year to date:
  • Site-wide: 36,590
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  • Site-wide: 21,464

Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19

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  • Site-wide: 17,080
  • In immunology: 690
• Year to date:
  • Site-wide: 11,264
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  • Site-wide: 19,655

SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19

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  • Site-wide: 17,290
  • In infectious diseases: 2,022
• Year to date:
  • Site-wide: 65,574
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  • Site-wide: 74,382

SARS-CoV-2 Seroprevalence Among Parturient Women

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  • Site-wide: 18,544
  • In infectious diseases: 2,130
• Year to date:
  • Site-wide: 42,497
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  • Site-wide: 30,615

Glycan Clock Forecasts Human Influenza A Virus Hemagglutinin Evolution

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  • Site-wide: 25,193
  • In microbiology: 1,367
• Year to date:
  • Site-wide: 142,640
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  • Site-wide: 163,731

Transplacental Transfer of SARS-CoV-2 Antibodies

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  • Site-wide: 26,975
  • In infectious diseases: 2,547
• Year to date:
  • Site-wide: 73,429
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  • Site-wide: 64,137

Mapping person-to-person variation in viral mutations that escape polyclonal serum targeting influenza hemagglutinin

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  • Site-wide: 42,357
  • In microbiology: 2,406
• Year to date:
  • Site-wide: 104,392
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  • Site-wide: 131,116

Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility

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  • Site-wide: 45,077
  • In infectious diseases: 3,284
• Year to date:
  • Site-wide: 138,199
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  • Site-wide: 157,656

Complete mapping of viral escape from neutralizing antibodies

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  • Site-wide: 49,707
  • In microbiology: 2,734
• Year to date:
  • Site-wide: 176,932
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  • Site-wide: 183,263

Potential antigenic mismatch of the H3N2 component of the 2019 Southern Hemisphere influenza vaccine

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  • Site-wide: 60,600
  • In microbiology: 3,427
• Year to date:
  • Site-wide: 144,052
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  • Site-wide: 174,005

Despite egg-adaptive mutations, the 2012-13 H3N2 influenza vaccine induced comparable antibody titers to the intended strain

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  • Site-wide: 78,921
  • In epidemiology: 3,269
• Year to date:
  • Site-wide: 190,236
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  • Site-wide: 187,274

Vaccination reshapes the virus-specific T cell repertoire in unexposed adults

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  • Site-wide: 80,245
  • In immunology: 2,492
• Year to date:
  • Site-wide: 85,005
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  • Site-wide: 63,160

Identification of antibodies targeting the H3N2 hemagglutinin receptor binding site following vaccination of humans

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  • Site-wide: 85,106
  • In microbiology: 5,156
• Year to date:
  • Site-wide: 155,885
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  • Site-wide: 163,353

Assessing the protective potential of H1N1 influenza virus hemagglutinin head and stalk antibodies in humans

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  • Site-wide: 93,005
  • In microbiology: 5,681
• Year to date:
  • Site-wide: 174,564
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  • Site-wide: 147,927

An egg-derived sulfated N-Acetyllactosamine glycan is an antigenic decoy of influenza virus vaccines

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  • Site-wide: 112,275
  • In immunology: 3,283
• Year to date:
  • Site-wide: 103,241
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  • Site-wide: 122,617

Antigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine

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  • Site-wide: 113,155
  • In infectious diseases: 5,244
• Year to date:
  • Site-wide: 156,980
• Since beginning of last month:
  • Site-wide: 120,417

Pre-existing immunity provides a barrier to airborne transmission of influenza viruses

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  • Site-wide: 115,939
  • In microbiology: 7,353
• Year to date:
  • Site-wide: 184,144
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  • Site-wide: 167,238

Identification of human vaccinees that possess antibodies targeting the egg-adapted hemagglutinin receptor binding site of an H1N1 influenza vaccine strain

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  • Site-wide: 119,249
  • In microbiology: 7,701
• Year to date:
  • Site-wide: 173,500
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  • Site-wide: 161,444

Sera from individuals with narrowly focused influenza virus antibodies rapidly select viral escape mutations in ovo

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  • Site-wide: 124,701
  • In microbiology: 8,005
• Year to date:
  • Site-wide: 185,980
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  • Site-wide: 187,681

The 2009 pandemic H1N1 hemagglutinin stalk remained antigenically stable after circulating in humans for a decade

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  • Site-wide: 163,643
  • In microbiology: 12,261
• Year to date:
  • Site-wide: 17,890
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  • Site-wide: 72,860