Author: Sean PJ Whelan

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Preprints

Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape

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Glucocorticoids and B Cell Depleting Agents Substantially Impair Immunogenicity of mRNA Vaccines to SARS-CoV-2

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Structural basis for broad sarbecovirus neutralization by a human monoclonal antibody

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Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization

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Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition

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Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2

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A public vaccine-induced human antibody protects against SARS-CoV-2 and emerging variants

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Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor

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Nitazoxanide and JIB-04 have broad-spectrum antiviral activity and inhibit SARS-CoV-2 replication in cell culture and coronavirus pathogenesis in a pig model

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Reconstruction of the cell entry pathway of an extinct virus

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Human, Nonhuman Primate, and Bat Cells Are Broadly Susceptible to Tibrovirus Particle Cell Entry

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Vesicular stomatitis virus transcription is inhibited by TRIM69 in the interferon-induced antiviral state

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Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

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Messenger RNA cap methylation by PCIF1 attenuates the interferon-β induced antiviral state

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Human immunoglobulin from transchromosomic bovines hyperimmunized with SARS-CoV-2 spike antigen efficiently neutralizes viral variants.

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Vesicular stomatitis virus chimeras expressing the Oropouche virus glycoproteins elicit protective immune responses in mice.

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