Author: Paul M Ridker

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Preprints

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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  • Site-wide: 3,502
  • In genetics: 165
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  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 53,098

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

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  • Site-wide: 4,649
  • In genetics: 229
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  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 103,188

Efficient Bayesian mixed model analysis increases association power in large cohorts

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  • Site-wide: 5,367
  • In genetics: 269
• Year to date:
  • Site-wide: 17,324
• Since beginning of last month:
  • Site-wide: 36,331

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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  • Site-wide: 7,278
  • In genetics: 364
• Year to date:
  • Site-wide: 23,654
• Since beginning of last month:
  • Site-wide: 70,160

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 8,682
  • In genetics: 448
• Year to date:
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  • Site-wide: 25,388

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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  • Site-wide: 10,433
  • In genetics: 537
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  • Site-wide: None
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  • Site-wide: 101,264

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

• Downloaded 1,224 times
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  • Site-wide: 13,340
  • In genomics: 1,472
• Year to date:
  • Site-wide: 28,314
• Since beginning of last month:
  • Site-wide: 68,892

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

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  • Site-wide: 25,549
  • In genetics: 1,309
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• Since beginning of last month:
  • Site-wide: 91,163

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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  • Site-wide: 26,489
  • In genetics: 1,350
• Year to date:
  • Site-wide: 9,524
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  • Site-wide: 16,049

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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  • Site-wide: 28,526
  • In genomics: 2,654
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  • Site-wide: None
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  • Site-wide: 109,334

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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  • Site-wide: 33,472
  • In genetics: 1,685
• Year to date:
  • Site-wide: 9,565
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  • Site-wide: 7,308

Prospective Evaluation of a Breast Cancer Risk Model Integrating Classical Risk Factors and Polygenic Risk in 15 Cohorts from Six Countries

• Downloaded 552 times
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  • Site-wide: 40,720
  • In epidemiology: 1,853
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  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 89,059

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

• Downloaded 544 times
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  • Site-wide: 41,489
  • In genetics: 2,052
• Year to date:
  • Site-wide: 39,215
• Since beginning of last month:
  • Site-wide: 52,916

A multivariate genome-wide association analysis of 10 LDL subfractions, and their response to statin treatment, in 1868 Caucasians

• Downloaded 507 times
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  • Site-wide: 45,176
  • In genetics: 2,211
• Year to date:
  • Site-wide: 44,224
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  • Site-wide: 61,079

Genetics of fasting indices of glucose homeostasis using GWIS unravels tight relationships with inflammatory markers

• Downloaded 327 times
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  • Site-wide: 70,059
  • In genetics: 3,340
• Year to date:
  • Site-wide: 55,684
• Since beginning of last month:
  • Site-wide: 55,066

Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

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  • Site-wide: 79,408
  • In epidemiology: 3,193
• Year to date:
  • Site-wide: 25,680
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  • Site-wide: 83,007

Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

• Downloaded 254 times
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  • Site-wide: 84,324
  • In genetics: 3,925
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 99,555