Author: Paul M Ridker

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Preprints

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

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  • Site-wide: 3,953
  • In genetics: 168
• Year to date:
  • Site-wide: 52,683
• Since beginning of last month:
  • Site-wide: 66,453

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

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  • Site-wide: 5,311
  • In genetics: 244
• Year to date:
  • Site-wide: 89,865
• Since beginning of last month:
  • Site-wide: 92,954

Efficient Bayesian mixed model analysis increases association power in large cohorts

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  • Site-wide: 6,128
  • In genetics: 292
• Year to date:
  • Site-wide: 61,905
• Since beginning of last month:
  • Site-wide: 54,130

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

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  • Site-wide: 8,334
  • In genetics: 391
• Year to date:
  • Site-wide: 85,043
• Since beginning of last month:
  • Site-wide: 81,681

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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  • Site-wide: 9,826
  • In genetics: 469
• Year to date:
  • Site-wide: 61,841
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  • Site-wide: 40,345

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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  • Site-wide: 11,676
  • In genetics: 569
• Year to date:
  • Site-wide: 85,440
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  • Site-wide: 100,122

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

• Downloaded 1,243 times
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  • Site-wide: 15,126
  • In genomics: 1,569
• Year to date:
  • Site-wide: 85,847
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  • Site-wide: 114,514

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

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  • Site-wide: 26,731
  • In genetics: 1,300
• Year to date:
  • Site-wide: 27,088
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  • Site-wide: 19,389

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

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  • Site-wide: 27,403
  • In genetics: 1,331
• Year to date:
  • Site-wide: 59,638
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  • Site-wide: 64,856

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

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  • Site-wide: 28,939
  • In genetics: 1,404
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  • Site-wide: 13,195
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  • Site-wide: 8,904

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

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  • Site-wide: 31,271
  • In genomics: 2,798
• Year to date:
  • Site-wide: 92,614
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  • Site-wide: 103,016

Prospective Evaluation of a Breast Cancer Risk Model Integrating Classical Risk Factors and Polygenic Risk in 15 Cohorts from Six Countries

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  • Site-wide: 41,659
  • In epidemiology: 1,979
• Year to date:
  • Site-wide: 53,377
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  • Site-wide: 42,047

Genetic insights into the biological mechanisms governing human ovarian ageing

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  • Site-wide: 43,335
  • In sexual and reproductive health: 18
• Year to date:
  • Site-wide: 2,215
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  • Site-wide: 6,029

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

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  • Site-wide: 44,476
  • In genetics: 2,089
• Year to date:
  • Site-wide: 67,647
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  • Site-wide: 108,368

A multivariate genome-wide association analysis of 10 LDL subfractions, and their response to statin treatment, in 1868 Caucasians

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  • Site-wide: 49,506
  • In genetics: 2,317
• Year to date:
  • Site-wide: 94,527
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  • Site-wide: 119,084

Genetics of fasting indices of glucose homeostasis using GWIS unravels tight relationships with inflammatory markers

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  • Site-wide: 71,935
  • In genetics: 3,287
• Year to date:
  • Site-wide: 58,148
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  • Site-wide: 60,919

Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

• Downloaded 308 times
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  • Site-wide: 83,154
  • In genetic and genomic medicine: 294
• Year to date:
  • Site-wide: 5,564
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  • Site-wide: 18,501

Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

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  • Site-wide: 84,638
  • In epidemiology: 3,478
• Year to date:
  • Site-wide: 74,255
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  • Site-wide: 73,868

Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

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  • Site-wide: 91,651
  • In genetics: 4,136
• Year to date:
  • Site-wide: 121,590
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  • Site-wide: 105,957