Author: David M Hougaard

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Preprints

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

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Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism

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  • Site-wide: 740
  • In genetics: 22
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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Common risk variants identified in autism spectrum disorder

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  • Site-wide: 1,050
  • In genetics: 34
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Genomewide association study identifies 30 loci associated with bipolar disorder

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Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia

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  • In genetic and genomic medicine: 11
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Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum

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Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders

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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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ASD and ADHD have a similar burden of rare protein-truncating variants

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Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population

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  • Site-wide: 9,139
  • In genetics: 451
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  • Site-wide: 70,513
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Genome-wide association study implicates CHRNA2 in cannabis use disorder

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  • Site-wide: 9,469
  • In genomics: 1,060
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  • Site-wide: 23,161
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Genome-wide association study of over 40,000 bipolar disorder cases provides novel biological insights

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  • Site-wide: 10,129
  • In psychiatry and clinical psychology: 32
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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

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  • In genetics: 594
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A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

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  • Site-wide: 11,938
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Genome-wide Association Study of Anxiety and Stress-related Disorders in the iPSYCH Cohort

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A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator

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  • Site-wide: 15,828
  • In genetics: 805
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The genetic architecture of sporadic and recurrent miscarriage

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  • In genetics: 851
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Genome-wide association study of school grades identifies a genetic overlap between language ability, psychopathology and creativity

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  • Site-wide: 17,608
  • In genomics: 1,831
• Year to date:
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Mitochondrial DNA SNPs associated with Schizophrenia exhibit Highly Variable Inter-allelic Haplogroup Affiliation and Nuclear Genogeographic Affinity: Bi-Genomic Linkage Disequilibrium raises Major Concerns for Link to Disease

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  • Site-wide: 17,937
  • In genomics: 1,861
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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders

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Complex spatio-temporal distribution and genogeographic affinity of mitochondrial DNA haplogroups in 24,216 Danes

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  • Site-wide: 23,238
  • In genomics: 2,269
• Year to date:
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The iPSYCH2012 case-cohort sample: New directions for unravelling genetic and environmental architectures of severe mental disorders

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  • Site-wide: 28,503
  • In genetics: 1,422
• Year to date:
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Untargeted metabolomic study of autism in newborn screening samples: a pilot study

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  • Site-wide: 40,993
  • In psychiatry and clinical psychology: 127
• Year to date:
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  • Site-wide: 24,303

Identification of risk variants and characterization of the polygenic architecture of disruptive behavior disorders in the context of ADHD

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  • Site-wide: 43,122
  • In genomics: 3,539
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Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

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Meta-analysis of Scandinavian Schizophrenia Exomes

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Gestational-age-dependent development of the neonatal metabolome

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Polygenic prediction of school performance in children with and without psychiatric disorders

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Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders – findings from a Danish population-based study

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  • Site-wide: 86,774
  • In bioinformatics: 7,750
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The iPSYCH2015 Case-Cohort sample: updated directions for unravelling genetic and environmental architectures of severe mental disorders

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  • Site-wide: 117,301
  • In epidemiology: 4,742
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Genome-wide association study of febrile seizures identifies seven new loci implicating fever response and neuronal excitability genes

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  • Site-wide: 119,404
  • In genetic and genomic medicine: 540
• Year to date:
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Mendelian randomization study of spermine oxidase and cancer risk

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  • Site-wide: 123,843
  • In genetic and genomic medicine: 571
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