Author: Harry Hemingway

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Preprints

An Informatics Consult approach for generating clinical evidence for treatment decisions

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Identifying high-risk groups for change in weight and body mass index: population cohort of 11 million measurements in 2.3 million adults

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Estimating excess 1- year mortality from COVID-19 according to underlying conditions and age in England: a rapid analysis using NHS health records in 3.8 million adults

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  • Site-wide: 473
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  • Site-wide: 1,283

Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary prevention

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  • Site-wide: 2,336
  • In genetics: 98
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Machine learning models in electronic health records can outperform conventional survival models for predicting patient mortality in coronary artery disease

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  • Site-wide: 3,903
  • In epidemiology: 354
• Year to date:
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Flipping the odds of drug development success through human genomics

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  • In genomics: 1,037
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Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

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  • Site-wide: 10,511
  • In genetics: 532
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Estimating excess mortality in people with cancer and multimorbidity in the COVID-19 emergency

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  • Site-wide: 10,907
  • In oncology: 9
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  • Site-wide: 11,969
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Covid-19 infection and attributable mortality in UK Long Term Care Facilities: Cohort study using active surveillance and electronic records (March-June 2020)

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  • Site-wide: 14,454
  • In infectious diseases: 1,282
• Year to date:
  • Site-wide: 18,187
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UK phenomics platform for developing and validating EHR phenotypes: CALIBER

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  • Site-wide: 21,405
  • In epidemiology: 1,170
• Year to date:
  • Site-wide: 31,386
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  • Site-wide: 20,968

Excess deaths in people with cardiovascular diseases during the COVID-19 pandemic.

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  • Site-wide: 22,248
  • In cardiovascular medicine: 29
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  • Site-wide: 43,053
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  • Site-wide: 12,216

Coronavirus (COVID-19) infection in children at a specialist centre: outcome and implications of underlying high-risk comorbidities in a paediatric population

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  • Site-wide: 27,069
  • In pediatrics: 23
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  • Site-wide: 58,634
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Obesity during the COVID-19 pandemic: cause of high risk or an effect of lockdown? A population-based electronic health record analysis in 1 958 184 individuals.

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  • Site-wide: 29,600
  • In health policy: 65
• Year to date:
  • Site-wide: 32,913
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Protocol for the development and evaluation of a tool for predicting risk of short-term adverse outcomes due to COVID-19 in the general UK population

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  • Site-wide: 40,610
  • In epidemiology: 1,871
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  • Site-wide: 9,677
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Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

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  • In genetics: 2,090
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Clinical academic research in the time of Corona: a simulation study in England and a call for action

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  • In health systems and quality improvement: 45
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Analyzing the heterogeneity of rule-based EHR phenotyping algorithms in CALIBER and the UK Biobank

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  • In bioinformatics: 5,845
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Weight change and the incidence of cardiovascular diseases in adults with normal weight, overweight and obesity without chronic diseases; emulating trials using electronic health records

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  • Site-wide: 66,226
  • In cardiovascular medicine: 91
• Year to date:
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Bleeding in cardiac patients prescribed antithrombotic drugs: Electronic health record phenotyping algorithms, incidence, trends and prognosis

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  • Site-wide: 71,310
  • In epidemiology: 2,920
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  • Site-wide: 78,363

A semi-supervised approach for rapidly creating clinical biomarker phenotypes in the UK Biobank using different primary care EHR and clinical terminology systems.

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  • Site-wide: 73,019
  • In health informatics: 229
• Year to date:
  • Site-wide: 114,438
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Body mass index and heart failure risk: a cohort study in 1.5 million individuals and Mendelian randomisation analysis

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  • Site-wide: 82,742
  • In cardiovascular medicine: 122
• Year to date:
  • Site-wide: 34,633
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  • Site-wide: 44,977

The 4C Initiative (Clinical Care for Cardiovascular disease in the COVID-19 pandemic): monitoring the indirect impact of the coronavirus pandemic on services for cardiovascular diseases in the UK

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  • Site-wide: 86,168
  • In public and global health: 847
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  • Site-wide: 63,986