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Author: Eric Vallabh Minikel

Rankings

  • All-time downloads: 56,611 (rank: 718 out of 426,414)
  • Categories:
    • biochemistry: 819 (rank: 4,573 (tie) out of 20,785)
    • genetics: 2,008 (rank: 8,018 (tie) out of 38,003)
    • genomics: 52,015 (rank: 127 out of 44,644)
    • neuroscience: 1,769 (rank: 10,130 (tie) out of 72,387)

Downloads per author, site-wide

Preprints

The mutational constraint spectrum quantified from variation in 141,456 humans

genomics more details view paper
  • Downloaded 23,222 times
  • Download rankings, all-time:
    • Site-wide: 71 out of 100,936
    • In genomics: 9 out of 6,255
  • Year to date:
    • Site-wide: 151 out of 100,936
  • Since beginning of last month:
    • Site-wide: 361 out of 100,936

Analysis of protein-coding genetic variation in 60,706 humans

genomics more details view paper
  • Downloaded 21,837 times
  • Download rankings, all-time:
    • Site-wide: 77 out of 100,936
    • In genomics: 10 out of 6,255
  • Year to date:
    • Site-wide: 18,742 out of 100,936
  • Since beginning of last month:
    • Site-wide: 24,124 out of 100,936

Evaluating potential drug targets through human loss-of-function genetic variation

genomics more details view paper
  • Downloaded 4,425 times
  • Download rankings, all-time:
    • Site-wide: 1,098 out of 100,936
    • In genomics: 219 out of 6,255
  • Year to date:
    • Site-wide: 3,554 out of 100,936
  • Since beginning of last month:
    • Site-wide: 8,485 out of 100,936

Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples

genetics more details view paper
  • Downloaded 2,008 times
  • Download rankings, all-time:
    • Site-wide: 4,169 out of 100,936
    • In genetics: 303 out of 5,022
  • Year to date:
    • Site-wide: 51,527 out of 100,936
  • Since beginning of last month:
    • Site-wide: 33,139 out of 100,936

Human loss-of-function variants suggest that partial LRRK2 inhibition is a safe therapeutic strategy for Parkinson’s disease

genomics more details view paper
  • Downloaded 1,867 times
  • Download rankings, all-time:
    • Site-wide: 4,748 out of 100,936
    • In genomics: 772 out of 6,255
  • Year to date:
    • Site-wide: 10,385 out of 100,936
  • Since beginning of last month:
    • Site-wide: 24,464 out of 100,936

Age of onset in genetic prion disease and the design of preventive clinical trials

neuroscience more details view paper
  • Downloaded 790 times
  • Download rankings, all-time:
    • Site-wide: 19,488 out of 100,936
    • In neuroscience: 3,167 out of 17,983
  • Year to date:
    • Site-wide: 32,262 out of 100,936
  • Since beginning of last month:
    • Site-wide: 49,590 out of 100,936

Response to Shah et al: Using high-resolution variant frequencies empowers clinical genome interpretation and enables investigation of genetic architecture

genomics more details view paper
  • Downloaded 664 times
  • Download rankings, all-time:
    • Site-wide: 25,168 out of 100,936
    • In genomics: 2,737 out of 6,255
  • Year to date:
    • Site-wide: 85,298 out of 100,936
  • Since beginning of last month:
    • Site-wide: 62,825 out of 100,936

Multimodal small-molecule screening for human prion protein binders

biochemistry more details view paper
  • Downloaded 559 times
  • Download rankings, all-time:
    • Site-wide: 31,627 out of 100,936
    • In biochemistry: 895 out of 3,446
  • Year to date:
    • Site-wide: 6,393 out of 100,936
  • Since beginning of last month:
    • Site-wide: 25,119 out of 100,936

Domain-specific quantification of prion protein in cerebrospinal fluid by targeted mass spectrometry

neuroscience more details view paper
  • Downloaded 502 times
  • Download rankings, all-time:
    • Site-wide: 36,360 out of 100,936
    • In neuroscience: 6,206 out of 17,983
  • Year to date:
    • Site-wide: 51,626 out of 100,936
  • Since beginning of last month:
    • Site-wide: 51,077 out of 100,936

Prion protein lowering is a disease-modifying therapy across prion strains, disease stages, and endpoints

neuroscience more details view paper
  • Downloaded 477 times
  • Download rankings, all-time:
    • Site-wide: 38,667 out of 100,936
    • In neuroscience: 6,632 out of 17,983
  • Year to date:
    • Site-wide: 8,199 out of 100,936
  • Since beginning of last month:
    • Site-wide: 15,316 out of 100,936

Characterization of the prion protein binding properties of antisense oligonucleotides

biochemistry more details view paper
  • Downloaded 260 times
  • Download rankings, all-time:
    • Site-wide: 67,933 out of 100,936
    • In biochemistry: 2,163 out of 3,446
  • Year to date:
    • Site-wide: 68,491 out of 100,936
  • Since beginning of last month:
    • Site-wide: 67,507 out of 100,936

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  • 20 Oct 2020: Support for sorting preprints using Twitter activity has been removed, at least temporarily, until a new source of social media activity data becomes available.
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