Author: Peng Wang

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Preprints

Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

• Downloaded 36,475 times
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  • Site-wide: 287
  • In immunology: 20
• Year to date:
  • Site-wide: 16
• Since beginning of last month:
  • Site-wide: 3

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

• Downloaded 14,859 times
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  • Site-wide: 827
  • In immunology: 40
• Year to date:
  • Site-wide: 2,763
• Since beginning of last month:
  • Site-wide: 2,554

BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection

• Downloaded 14,224 times
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  • Site-wide: 875
  • In immunology: 45
• Year to date:
  • Site-wide: 841
• Since beginning of last month:
  • Site-wide: 588

Brain-wide single neuron reconstruction reveals morphological diversity in molecularly defined striatal, thalamic, cortical and claustral neuron types

• Downloaded 7,463 times
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  • Site-wide: 2,011
  • In neuroscience: 86
• Year to date:
  • Site-wide: 6,244
• Since beginning of last month:
  • Site-wide: 18,191

Glycoengineering of NK cells with glycan ligands of CD22 and selectins for B-cell lymphoma therapy

• Downloaded 6,443 times
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  • Site-wide: 2,473
  • In bioengineering: 21
• Year to date:
  • Site-wide: 38,477
• Since beginning of last month:
  • Site-wide: 39,719

A multimodal cell census and atlas of the mammalian primary motor cortex

• Downloaded 5,564 times
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  • Site-wide: 3,026
  • In neuroscience: 169
• Year to date:
  • Site-wide: 17,608
• Since beginning of last month:
  • Site-wide: 18,666

Characterizations of enhanced infectivity and antibody evasion of Omicron BA.2.75

• Downloaded 5,065 times
• Download rankings, all-time:
  • Site-wide: 3,433
  • In immunology: 142
• Year to date:
  • Site-wide: 2,092
• Since beginning of last month:
  • Site-wide: 2,328

A Randomized, Single-blind, Group sequential, Active-controlled Study to evaluate the clinical efficacy and safety of α-Lipoic acid for critically ill patients with coronavirus disease 2019(COVID-19)

• Downloaded 3,675 times
• Download rankings, all-time:
  • Site-wide: 5,418
  • In pharmacology and therapeutics: 18
• Year to date:
  • Site-wide: 29,069
• Since beginning of last month:
  • Site-wide: 54,026

Epigallocatechin Gallate from Green Tea Effectively Blocks Infection of SARS-CoV-2 and New Variants by Inhibiting Spike Binding to ACE2 Receptor

• Downloaded 3,656 times
• Download rankings, all-time:
  • Site-wide: 5,460
  • In microbiology: 365
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 45,199

Omicron BA.2 specifically evades broad sarbecovirus neutralizing antibodies

• Downloaded 2,293 times
• Download rankings, all-time:
  • Site-wide: 10,919
  • In immunology: 438
• Year to date:
  • Site-wide: 5,303
• Since beginning of last month:
  • Site-wide: 8,542

Multi-color 4D superresolution light-sheet microscopy reveals organelle interactions at isotropic 100-nm resolution and sub-second timescales

• Downloaded 1,937 times
• Download rankings, all-time:
  • Site-wide: 14,109
  • In biophysics: 321
• Year to date:
  • Site-wide: 22,431
• Since beginning of last month:
  • Site-wide: 36,879

Compartmental Neuropeptide Release Measured Using a New Oxytocin Sensor

• Downloaded 1,918 times
• Download rankings, all-time:
  • Site-wide: 14,321
  • In neuroscience: 1,588
• Year to date:
  • Site-wide: 14,589
• Since beginning of last month:
  • Site-wide: 4,908

Long-range functional coupling predicts performance: oscillatory EEG networks in multisensory processing

• Downloaded 1,509 times
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  • Site-wide: 20,869
  • In neuroscience: 2,387
• Year to date:
  • Site-wide: 117,255
• Since beginning of last month:
  • Site-wide: 144,847

Sensitive detection and quantification of SARS-CoV-2 in saliva

• Downloaded 1,411 times
• Download rankings, all-time:
  • Site-wide: 23,253
  • In infectious diseases: 2,508
• Year to date:
  • Site-wide: 93,504
• Since beginning of last month:
  • Site-wide: 44,094

Anatomical and Functional Gradients Shape Dynamic Functional Connectivity in the Human Brain

• Downloaded 1,406 times
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  • Site-wide: 23,407
  • In neuroscience: 2,760
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 62,093

Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents

• Downloaded 1,388 times
• Download rankings, all-time:
  • Site-wide: 23,889
  • In immunology: 1,022
• Year to date:
  • Site-wide: 1,522
• Since beginning of last month:
  • Site-wide: 1,090

Human Beta Cell Mass Expansion In Vivo With A Harmine and Exendin-4 Combination: Quantification and Visualization By iDISCO+ 3D Imaging

• Downloaded 1,112 times
• Download rankings, all-time:
  • Site-wide: 33,890
  • In cell biology: 1,278
• Year to date:
  • Site-wide: 49,849
• Since beginning of last month:
  • Site-wide: 11,632

Single Cell Transcriptomic Landscape of Diabetic Foot Ulcers

• Downloaded 1,091 times
• Download rankings, all-time:
  • Site-wide: 34,892
  • In genomics: 2,804
• Year to date:
  • Site-wide: 102,464
• Since beginning of last month:
  • Site-wide: 113,433

Correlation of vaccine-elicited antibody levels and neutralizing activities against SARS-CoV-2 and its variants

• Downloaded 1,086 times
• Download rankings, all-time:
  • Site-wide: 35,076
  • In microbiology: 2,027
• Year to date:
  • Site-wide: 146,894
• Since beginning of last month:
  • Site-wide: 97,619

Modulation of Siglec-7 Signaling via in situ Created High-affinity cis-Ligands

• Downloaded 1,065 times
• Download rankings, all-time:
  • Site-wide: 36,148
  • In biochemistry: 860
• Year to date:
  • Site-wide: 122,863
• Since beginning of last month:
  • Site-wide: 100,704

Optimization of a Modular Steroid-Inducible Gene Expression System for Use in Rice

• Downloaded 1,015 times
• Download rankings, all-time:
  • Site-wide: 38,974
  • In plant biology: 668
• Year to date:
  • Site-wide: 65,007
• Since beginning of last month:
  • Site-wide: 143,910

In-situ observation of mitochondrial biogenesis as the early event of apoptosis

• Downloaded 992 times
• Download rankings, all-time:
  • Site-wide: 40,377
  • In cell biology: 1,543
• Year to date:
  • Site-wide: 164,019
• Since beginning of last month:
  • Site-wide: 123,597

Effects of graphene oxide and graphite on soil bacterial and fungal diversity

• Downloaded 986 times
• Download rankings, all-time:
  • Site-wide: 40,799
  • In microbiology: 2,348
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 145,182

A human disease model of SARS-CoV-2-induced lung injury and immune responses with a microengineered organ chip

• Downloaded 940 times
• Download rankings, all-time:
  • Site-wide: 43,895
  • In bioengineering: 868
• Year to date:
  • Site-wide: 84,616
• Since beginning of last month:
  • Site-wide: 80,322

DNA 5-Hydroxymethylcytosines from Cell-free Circulating DNA as Diagnostic Biomarkers for Human Cancers

• Downloaded 919 times
• Download rankings, all-time:
  • Site-wide: 45,368
  • In cancer biology: 1,302
• Year to date:
  • Site-wide: 52,640
• Since beginning of last month:
  • Site-wide: 150,093

Human pseudoislet system enables detection of differences in G-protein-coupled-receptor signaling pathways between α and β cells

• Downloaded 821 times
• Download rankings, all-time:
  • Site-wide: 53,965
  • In cell biology: 2,231
• Year to date:
  • Site-wide: 121,681
• Since beginning of last month:
  • Site-wide: 187,833

Metagenomic Study Revealed the Potential Role of the Gut Microbiome in Gout

• Downloaded 809 times
• Download rankings, all-time:
  • Site-wide: 55,130
  • In rheumatology: 42
• Year to date:
  • Site-wide: 128,937
• Since beginning of last month:
  • Site-wide: 126,811

Identification of spatially variable genes with graph cuts

• Downloaded 778 times
• Download rankings, all-time:
  • Site-wide: 58,424
  • In bioinformatics: 5,729
• Year to date:
  • Site-wide: 99,455
• Since beginning of last month:
  • Site-wide: 119,490

A role for heritable transcriptomic variation in maize adaptation to temperate environments

• Downloaded 684 times
• Download rankings, all-time:
  • Site-wide: 70,496
  • In bioinformatics: 7,297
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 41,754

Modeling SARS-CoV-2 infection in vitro with a human intestine-on-chip device

• Downloaded 617 times
• Download rankings, all-time:
  • Site-wide: 80,677
  • In bioengineering: 1,617
• Year to date:
  • Site-wide: 125,958
• Since beginning of last month:
  • Site-wide: 131,901

Medicago SPX1 and SPX3 regulate phosphate homeostasis, mycorrhizal colonization and arbuscule degradation

• Downloaded 609 times
• Download rankings, all-time:
  • Site-wide: 82,025
  • In plant biology: 2,010
• Year to date:
  • Site-wide: 93,003
• Since beginning of last month:
  • Site-wide: 157,836

Delta phase resets mediate non-rhythmic temporal prediction

• Downloaded 579 times
• Download rankings, all-time:
  • Site-wide: 87,601
  • In neuroscience: 12,379
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 154,350

Genome-wide survey and expression analysis of the SLAC/SLAH gene family in pear (Pyrus bretschneideri) and other members of the Rosaceae

• Downloaded 574 times
• Download rankings, all-time:
  • Site-wide: 88,465
  • In bioinformatics: 7,955
• Year to date:
  • Site-wide: 134,566
• Since beginning of last month:
  • Site-wide: 118,247

Filamentous recombinant human Tau activates primary astrocytes via an integrin receptor complex

• Downloaded 551 times
• Download rankings, all-time:
  • Site-wide: 93,079
  • In cell biology: 4,224
• Year to date:
  • Site-wide: 159,748
• Since beginning of last month:
  • Site-wide: 188,836

Natural variation in root exudation of GABA and DIMBOA impacts the maize root endosphere and rhizosphere microbiomes

• Downloaded 505 times
• Download rankings, all-time:
  • Site-wide: 103,188
  • In microbiology: 7,405
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 85,072

Effects of carbon nanotubes and derivatives of graphene oxide on soil bacterial diversity

• Downloaded 499 times
• Download rankings, all-time:
  • Site-wide: 104,490
  • In microbiology: 6,901
• Year to date:
  • Site-wide: 169,928
• Since beginning of last month:
  • Site-wide: 60,983

Orchestration of Chlorophyll and Carotenoid Biosynthesis by ORANGE Family Proteins in Plant

• Downloaded 488 times
• Download rankings, all-time:
  • Site-wide: 107,023
  • In plant biology: 2,881
• Year to date:
  • Site-wide: 43,847
• Since beginning of last month:
  • Site-wide: 25,368

SARS-CoV-2 causes human BBB injury and neuroinflammation indirectly in a linked organ chip platform

• Downloaded 468 times
• Download rankings, all-time:
  • Site-wide: 111,870
  • In bioengineering: 2,344
• Year to date:
  • Site-wide: 16,775
• Since beginning of last month:
  • Site-wide: 33,823

Dynamic Predictions: Oscillatory Mechanisms Underlying Multisensory Sequence Processing

• Downloaded 463 times
• Download rankings, all-time:
  • Site-wide: 113,153
  • In neuroscience: 16,394
• Year to date:
  • Site-wide: 143,213
• Since beginning of last month:
  • Site-wide: 211,604

A Novel Penalized Inverse-Variance Weighted Estimator for Mendelian Randomization with Applications to COVID-19 Outcomes

• Downloaded 459 times
• Download rankings, all-time:
  • Site-wide: 113,978
  • In epidemiology: 4,841
• Year to date:
  • Site-wide: 54,914
• Since beginning of last month:
  • Site-wide: 99,245

Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin

• Downloaded 457 times
• Download rankings, all-time:
  • Site-wide: 114,499
  • In biochemistry: 3,331
• Year to date:
  • Site-wide: 95,777
• Since beginning of last month:
  • Site-wide: 178,505

Soil chloride content influences the response of bacterial but not fungal diversity to silver nanoparticles entering soil via wastewater treatment processing

• Downloaded 450 times
• Download rankings, all-time:
  • Site-wide: 116,508
  • In microbiology: 7,841
• Year to date:
  • Site-wide: 175,026
• Since beginning of last month:
  • Site-wide: 38,131

Self-reported symptoms, self-reported viral testing result and seroprevalence of SARS CoV-2 among a community sample in Essex County New Jersey: A brief report.

• Downloaded 410 times
• Download rankings, all-time:
  • Site-wide: 127,200
  • In epidemiology: 5,275
• Year to date:
  • Site-wide: 109,527
• Since beginning of last month:
  • Site-wide: 113,629

Individual alpha power predicts language comprehension

• Downloaded 401 times
• Download rankings, all-time:
  • Site-wide: 129,737
  • In neuroscience: 18,999
• Year to date:
  • Site-wide: 79,411
• Since beginning of last month:
  • Site-wide: 49,683

Reporting amyloid beta levels via bioluminescence imaging with amyloid reservoirs inAlzheimer's disease models

• Downloaded 379 times
• Download rankings, all-time:
  • Site-wide: 136,302
  • In neuroscience: 20,015
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 111,371

Novel enzyme for dimethyl sulfide-releasing in bacteria reveals a missing route in the marine sulfur cycle

• Downloaded 351 times
• Download rankings, all-time:
  • Site-wide: 144,498
  • In ecology: 4,325
• Year to date:
  • Site-wide: 162,352
• Since beginning of last month:
  • Site-wide: 103,407

Response of Asplenium nidus to Drought Stress and Identification of Drought Tolerance Genes

• Downloaded 347 times
• Download rankings, all-time:
  • Site-wide: 145,749
  • In genetics: 5,457
• Year to date:
  • Site-wide: 123,639
• Since beginning of last month:
  • Site-wide: 185,959

Lin28a rejuvenates muscle stem cells via mitochondrial optimization

• Downloaded 342 times
• Download rankings, all-time:
  • Site-wide: 147,295
  • In cell biology: 7,022
• Year to date:
  • Site-wide: 28,781
• Since beginning of last month:
  • Site-wide: 72,294

HY5 Regulates GLK and GNC Transcription Factors to Orchestrate Photomorphogenesis in Arabidopsis thaliana

• Downloaded 320 times
• Download rankings, all-time:
  • Site-wide: 153,866
  • In plant biology: 4,468
• Year to date:
  • Site-wide: 7,522
• Since beginning of last month:
  • Site-wide: 8,058

Efficient detection of pre-proinsulin by double antibody sandwich ELISA

• Downloaded 294 times
• Download rankings, all-time:
  • Site-wide: 161,851
  • In bioengineering: 3,404
• Year to date:
  • Site-wide: 82,897
• Since beginning of last month:
  • Site-wide: 80,366

An oscillator ensemble model of sequence learning

• Downloaded 288 times
• Download rankings, all-time:
  • Site-wide: 163,742
  • In neuroscience: 23,927
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 203,783

Clonal hematopoiesis in individuals with ANKRD26 or ETV6 germline mutations

• Downloaded 277 times
• Download rankings, all-time:
  • Site-wide: 167,104
  • In genetics: 6,161
• Year to date:
  • Site-wide: 80,187
• Since beginning of last month:
  • Site-wide: 99,961

iEnhancer-CLA: Self-attention-based interpretable model for enhancers and their strength prediction

• Downloaded 251 times
• Download rankings, all-time:
  • Site-wide: 174,497
  • In bioinformatics: 13,228
• Year to date:
  • Site-wide: 80,261
• Since beginning of last month:
  • Site-wide: 115,640

Folate depletion induces erythroid differentiation through perturbation of de novo purine synthesis

• Downloaded 217 times
• Download rankings, all-time:
  • Site-wide: 183,382
  • In molecular biology: None
• Year to date:
  • Site-wide: 3,727
• Since beginning of last month:
  • Site-wide: 947

Mapping the adaptor protein complex interaction network in Arabidopsis identifies P34 as a common stability regulator

• Downloaded 199 times
• Download rankings, all-time:
  • Site-wide: 187,825
  • In plant biology: 5,316
• Year to date:
  • Site-wide: 41,062
• Since beginning of last month:
  • Site-wide: 28,224

ATF6 aggravates angiogenesis-osteogenesis coupling during ankylosing spondylitis by mediating FGF2 expression in chondrocytes

• Downloaded 191 times
• Download rankings, all-time:
  • Site-wide: 189,791
  • In molecular biology: 5,708
• Year to date:
  • Site-wide: 154,036
• Since beginning of last month:
  • Site-wide: 185,547

Total parenteral nutrition drives glucose metabolism disorders by modulating gut microbiota and its metabolites

• Downloaded 186 times
• Download rankings, all-time:
  • Site-wide: 190,861
  • In microbiology: 14,378
• Year to date:
  • Site-wide: 105,704
• Since beginning of last month:
  • Site-wide: 84,638

Development of Equine Polyclonal Antibodies as a Broad-Spectrum Therapy Against SARS-CoV-2 Variants

• Downloaded 176 times
• Download rankings, all-time:
  • Site-wide: 192,970
  • In immunology: 6,263
• Year to date:
  • Site-wide: 53,373
• Since beginning of last month:
  • Site-wide: 41,474

Repetition-attenuation of auditory N1 is modulated by the phonological representations of spoken word-forms

• Downloaded 155 times
• Download rankings, all-time:
  • Site-wide: 197,379
  • In neuroscience: 28,849
• Year to date:
  • Site-wide: 28,680
• Since beginning of last month:
  • Site-wide: 72,297

Clinical and molecular response of AML harboring non-canonical FLT3 N676K driver mutations to contemporary FLT3 inhibitors

• Downloaded 131 times
• Download rankings, all-time:
  • Site-wide: 201,854
  • In hematology: 182
• Year to date:
  • Site-wide: 13,749
• Since beginning of last month:
  • Site-wide: 46,672

Tumor landscape of epithelial ovarian cancer highlights that EGR1 drives tumor invasion at single-cell resolution

• Downloaded 124 times
• Download rankings, all-time:
  • Site-wide: 203,156
  • In bioinformatics: 14,771
• Year to date:
  • Site-wide: 130,485
• Since beginning of last month:
  • Site-wide: 108,011

Rational design by structural biology of industrializable, long-acting antihyperglycemic GLP-1 receptor agonists

• Downloaded 118 times
• Download rankings, all-time:
  • Site-wide: 204,346
  • In bioengineering: 4,430
• Year to date:
  • Site-wide: 181,472
• Since beginning of last month:
  • Site-wide: 168,864

Laminar Neural Dynamics of Auditory Evoked Responses: Computational Modeling of Local Field Potentials in Auditory Cortex of Non-Human Primates

• Downloaded 87 times
• Download rankings, all-time:
  • Site-wide: 209,869
  • In neuroscience: None
• Year to date:
  • Site-wide: 12,354
• Since beginning of last month:
  • Site-wide: 4,331

DEEP LEARNING IN THE PREDICTION OF ANGIOGRAPHY-PROVEN SEVERE CORONARY STENOSIS IN PATIENTS WITH APPARENTLY NORMAL ELECTROCARDIOGRAMS

• Downloaded 70 times
• Download rankings, all-time:
  • Site-wide: 213,100
  • In cardiovascular medicine: 852
• Year to date:
  • Site-wide: 21,768
• Since beginning of last month:
  • Site-wide: 12,475

IL-33 Involved in the Progression of Liver Fibrosis Through Innate Immunity Cells (MΦ) Regulated by ICOS/ICOSL Signaling in Early Stage of Mice Schistosomiasis

• Downloaded 68 times
• Download rankings, all-time:
  • Site-wide: 213,298
  • In immunology: 6,806
• Year to date:
  • Site-wide: 133,350
• Since beginning of last month:
  • Site-wide: 169,025

Frequency of incidental pathogenic and likely pathogenic germline variants detected via tumor-only mesothelioma genomic profiling

• Downloaded 68 times
• Download rankings, all-time:
  • Site-wide: 213,295
  • In oncology: 927
• Year to date:
  • Site-wide: 9,116
• Since beginning of last month:
  • Site-wide: 8,114