Author: Trever G. Bivona

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Preprints

Efficacy of SHP2 phosphatase inhibition in cancers with nucleotide-cycling oncogenic RAS, RAS-GTP dependent oncogenic BRAF and NF1 loss

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Continuous lineage recording reveals rapid, multidirectional metastasis in a lung cancer xenograft model in mouse

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Heterogeneity and targeted therapy-induced adaptations in lung cancer revealed by longitudinal single-cell RNA sequencing

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Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules

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Evolution and clinical impact of genetic epistasis within EGFR-mutant lung cancers

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Co-occurring alterations in the RAS-MAPK pathway limit response to MET inhibitor treatment in MET exon 14 skipping mutation positive lung cancer

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The CIC-DUX4 fusion oncoprotein drives metastasis and tumor growth via distinct downstream regulatory programs and therapeutic targets in sarcoma

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Synthetic essentiality of metabolic regulator PDHK1 in PTEN-deficient cells and cancers

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A tyrosine kinase protein interaction map reveals targetable EGFR network oncogenesis in lung cancer

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Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution

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Global analysis of epigenetic heterogeneity identifies divergent drivers of esophageal squamous cell carcinoma

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