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Author: Xiuqing Guo

  • ORCiD: http://orcid.org/0000-0002-5264-5068
  • Most recently observed institution: The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Rankings

  • All-time downloads: 53,871 (rank: 2,418 (tie) )
  • Categories:
    • bioinformatics: 276 (rank: 31,704 (tie) )
    • epidemiology: 905 (rank: 8,988 (tie) )
    • gastroenterology: 766 (rank: 349 (tie) )
    • genetic and genomic medicine: 3,153 (rank: 227 )
    • genetics: 30,025 (rank: 193 )
    • genomics: 17,417 (rank: 646 )
    • hiv aids: 973 (rank: 59 (tie) )
    • physiology: 356 (rank: 4,177 (tie) )

Downloads per author, site-wide

Preprints

Recovery of trait heritability from whole genome sequence data

genetics more details view paper
  • Downloaded 11,356 times
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    • Site-wide: 624
    • In genetics: 17
  • Year to date:
    • Site-wide: 2,083
  • Since beginning of last month:
    • Site-wide: 2,083

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

genomics more details view paper
  • Downloaded 8,033 times
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    • Site-wide: 986
    • In genomics: 92
  • Year to date:
    • Site-wide: 1,288
  • Since beginning of last month:
    • Site-wide: 1,288

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

genomics more details view paper
  • Downloaded 3,223 times
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    • Site-wide: 3,489
    • In genomics: 397
  • Year to date:
    • Site-wide: 62,768
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    • Site-wide: 62,768

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

genetics more details view paper
  • Downloaded 3,069 times
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    • Site-wide: 3,728
    • In genetics: 166
  • Year to date:
    • Site-wide: 35,664
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Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

genomics more details view paper
  • Downloaded 2,773 times
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    • Site-wide: 4,280
    • In genomics: 494
  • Year to date:
    • Site-wide: 6,541
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    • Site-wide: 6,541

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

genetics more details view paper
  • Downloaded 1,826 times
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    • Site-wide: 7,929
    • In genetics: 385
  • Year to date:
    • Site-wide: None
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    • Site-wide: None

Identification of type 2 diabetes loci in 433,540 East Asian individuals

genetics more details view paper
  • Downloaded 1,777 times
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    • Site-wide: 8,279
    • In genetics: 403
  • Year to date:
    • Site-wide: 27,891
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    • Site-wide: 27,891

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

genetics more details view paper
  • Downloaded 1,637 times
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    • Site-wide: 9,406
    • In genetics: 462
  • Year to date:
    • Site-wide: 72,619
  • Since beginning of last month:
    • Site-wide: 72,619

Novel genetic determinants of telomere length from a trans-ethnic analysis of 109,122 whole genome sequences in TOPMed

genetics more details view paper
  • Downloaded 1,315 times
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    • Site-wide: 12,989
    • In genetics: 659
  • Year to date:
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    • Site-wide: 7,337

Genetic architecture of gene expression traits across diverse populations

genomics more details view paper
  • Downloaded 1,206 times
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    • Site-wide: 14,793
    • In genomics: 1,559
  • Year to date:
    • Site-wide: 82,014
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    • Site-wide: 82,014

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

genetics more details view paper
  • Downloaded 1,187 times
  • Download rankings, all-time:
    • Site-wide: 15,156
    • In genetics: 780
  • Year to date:
    • Site-wide: 32,631
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    • Site-wide: 32,631

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

genetics more details view paper
  • Downloaded 1,026 times
  • Download rankings, all-time:
    • Site-wide: 18,905
    • In genetics: 943
  • Year to date:
    • Site-wide: 5,937
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    • Site-wide: 5,937

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

genetic and genomic medicine more details view paper
  • Downloaded 980 times
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    • Site-wide: 20,144
    • In genetic and genomic medicine: 60
  • Year to date:
    • Site-wide: 6,175
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    • Site-wide: 6,175

A high-resolution HLA reference panel capturing global population diversity enables multi-ethnic fine-mapping in HIV host response

hiv aids more details view paper
  • Downloaded 973 times
  • Download rankings, all-time:
    • Site-wide: 20,348
    • In hiv aids: 8
  • Year to date:
    • Site-wide: 10,222
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    • Site-wide: 10,222

Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole genome sequencing studies

genetics more details view paper
  • Downloaded 829 times
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    • Site-wide: 25,626
    • In genetics: 1,270
  • Year to date:
    • Site-wide: 84,595
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    • Site-wide: 84,595

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

genetics more details view paper
  • Downloaded 813 times
  • Download rankings, all-time:
    • Site-wide: 26,297
    • In genetics: 1,311
  • Year to date:
    • Site-wide: 43,447
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    • Site-wide: 43,447

A genome-wide association study for nonalcoholic fatty liver disease identifies novel genetic loci and trait-relevant candidate genes in the Million Veteran Program.

genetic and genomic medicine more details view paper
  • Downloaded 807 times
  • Download rankings, all-time:
    • Site-wide: 26,562
    • In genetic and genomic medicine: 77
  • Year to date:
    • Site-wide: 615
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    • Site-wide: 615

Machine learning enables new insights into clinical significance of and genetic contributions to liver fat accumulation

genetic and genomic medicine more details view paper
  • Downloaded 799 times
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    • Site-wide: 26,934
    • In genetic and genomic medicine: 78
  • Year to date:
    • Site-wide: 7,987
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    • Site-wide: 7,987

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

genetics more details view paper
  • Downloaded 794 times
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    • Site-wide: 27,156
    • In genetics: 1,353
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    • Site-wide: 26,470
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    • Site-wide: 26,470

rs641738C>T near MBOAT7 promotes steatosis, NASH, fibrosis and hepatocellular carcinoma in non-alcoholic fatty liver disease: a meta-analysis

gastroenterology more details view paper
  • Downloaded 766 times
  • Download rankings, all-time:
    • Site-wide: 28,588
    • In gastroenterology: 20
  • Year to date:
    • Site-wide: 22,684
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    • Site-wide: 22,684

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

genomics more details view paper
  • Downloaded 746 times
  • Download rankings, all-time:
    • Site-wide: 29,651
    • In genomics: 2,713
  • Year to date:
    • Site-wide: 67,772
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    • Site-wide: 67,772

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

genomics more details view paper
  • Downloaded 736 times
  • Download rankings, all-time:
    • Site-wide: 30,183
    • In genomics: 2,753
  • Year to date:
    • Site-wide: 53,903
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    • Site-wide: 53,903

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

genetics more details view paper
  • Downloaded 711 times
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    • Site-wide: 31,727
    • In genetics: 1,576
  • Year to date:
    • Site-wide: 13,852
  • Since beginning of last month:
    • Site-wide: 13,852

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

genetics more details view paper
  • Downloaded 709 times
  • Download rankings, all-time:
    • Site-wide: 31,843
    • In genetics: 1,587
  • Year to date:
    • Site-wide: 98,970
  • Since beginning of last month:
    • Site-wide: 98,970

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

genetics more details view paper
  • Downloaded 601 times
  • Download rankings, all-time:
    • Site-wide: 39,565
    • In genetics: 1,918
  • Year to date:
    • Site-wide: 63,951
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    • Site-wide: 63,951

Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

genetics more details view paper
  • Downloaded 504 times
  • Download rankings, all-time:
    • Site-wide: 49,052
    • In genetics: 2,351
  • Year to date:
    • Site-wide: 3,437
  • Since beginning of last month:
    • Site-wide: 3,437

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

genomics more details view paper
  • Downloaded 501 times
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    • Site-wide: 49,342
    • In genomics: 3,914
  • Year to date:
    • Site-wide: 106,960
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    • Site-wide: 106,960

Whole-Genome Association Analyses of Sleep-disordered Breathing Phenotypes in the NHLBI TOPMed Program

genetics more details view paper
  • Downloaded 426 times
  • Download rankings, all-time:
    • Site-wide: 58,850
    • In genetics: 2,795
  • Year to date:
    • Site-wide: 61,383
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    • Site-wide: 61,383

Impact of rare and common genetic variants on diabetes diagnosis by hemoglobin A1c in multi-ancestry cohorts: The Trans-Omics for Precision Medicine Program.

genetics more details view paper
  • Downloaded 374 times
  • Download rankings, all-time:
    • Site-wide: 66,941
    • In genetics: 3,132
  • Year to date:
    • Site-wide: 63,850
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    • Site-wide: 63,850

Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Humans and Mice

physiology more details view paper
  • Downloaded 356 times
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    • Site-wide: 69,853
    • In physiology: 520
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    • Site-wide: 48,327
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Multi-ethnic genome-wide association study of decomposed cardioelectric phenotypes illustrates strategies to identify and characterize evidence of shared genetic effects for complex traits

epidemiology more details view paper
  • Downloaded 350 times
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    • Site-wide: 70,929
    • In epidemiology: 2,945
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    • Site-wide: 110,496
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Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

epidemiology more details view paper
  • Downloaded 290 times
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    • Site-wide: 82,197
    • In epidemiology: 3,364
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    • Site-wide: 61,796
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    • Site-wide: 61,796

A system for phenotype harmonization in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program

genetics more details view paper
  • Downloaded 286 times
  • Download rankings, all-time:
    • Site-wide: 82,956
    • In genetics: 3,831
  • Year to date:
    • Site-wide: 25,835
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    • Site-wide: 25,835

Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries

bioinformatics more details view paper
  • Downloaded 276 times
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    • Site-wide: 85,116
    • In bioinformatics: 7,644
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Rare Non-coding Variation Identified by Large Scale Whole Genome Sequencing Reveals Unexplained Heritability of Type 2 Diabetes: Trans-Omics for Precision Medicine (TOPMed) Program

genetic and genomic medicine more details view paper
  • Downloaded 271 times
  • Download rankings, all-time:
    • Site-wide: 86,217
    • In genetic and genomic medicine: 288
  • Year to date:
    • Site-wide: 19,977
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    • Site-wide: 19,977

Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

genetics more details view paper
  • Downloaded 269 times
  • Download rankings, all-time:
    • Site-wide: 86,731
    • In genetics: 3,970
  • Year to date:
    • Site-wide: 102,500
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    • Site-wide: 102,500

Association of mitochondrial DNA copy number with cardiometabolic diseases in a large cross-sectional study of multiple ancestries

epidemiology more details view paper
  • Downloaded 265 times
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    • Site-wide: 87,444
    • In epidemiology: 3,560
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Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

genetics more details view paper
  • Downloaded 261 times
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    • Site-wide: 88,234
    • In genetics: 4,054
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    • Site-wide: 116,989
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GWAS of QRS Duration Identifies New Loci Specific to Hispanic/Latino Populations

genetics more details view paper
  • Downloaded 255 times
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    • Site-wide: 89,586
    • In genetics: 4,097
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    • Site-wide: 117,345
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    • Site-wide: 117,345

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

genomics more details view paper
  • Downloaded 199 times
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    • Site-wide: 101,758
    • In genomics: 6,010
  • Year to date:
    • Site-wide: 94,303
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    • Site-wide: 94,303

Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program

genetic and genomic medicine more details view paper
  • Downloaded 148 times
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    • Site-wide: 112,156
    • In genetic and genomic medicine: 486
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    • Site-wide: 6,417
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    • Site-wide: 6,417

BinomiRare: A carriers-only test for association of rare genetic variants with a binary outcome for mixed models and any case-control proportion

genetic and genomic medicine more details view paper
  • Downloaded 148 times
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    • Site-wide: 112,158
    • In genetic and genomic medicine: 487
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    • Site-wide: 6,420
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