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Author: Jerome I. Rotter

  • ORCiD: http://orcid.org/0000-0001-7191-1723
  • Most recently observed institution: The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California

Rankings

  • All-time downloads: 88,709 (rank: 1,422 )
  • Categories:
    • bioinformatics: 1,499 (rank: 9,750 (tie) )
    • epidemiology: 1,806 (rank: 5,546 )
    • genetic and genomic medicine: 6,038 (rank: 103 )
    • genetics: 45,257 (rank: 94 )
    • genomics: 33,278 (rank: 262 )
    • hematology: 467 (rank: 441 (tie) )
    • physiology: 364 (rank: 4,414 (tie) )

Downloads per author, site-wide

Preprints

Recovery of trait heritability from whole genome sequence data

genetics more details view paper
  • Downloaded 11,519 times
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    • Site-wide: 657
    • In genetics: 17
  • Year to date:
    • Site-wide: 2,814
  • Since beginning of last month:
    • Site-wide: 4,427

An open resource of structural variation for medical and population genetics

genomics more details view paper
  • Downloaded 10,981 times
  • Download rankings, all-time:
    • Site-wide: 708
    • In genomics: 53
  • Year to date:
    • Site-wide: 8,560
  • Since beginning of last month:
    • Site-wide: 12,569

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

genomics more details view paper
  • Downloaded 8,181 times
  • Download rankings, all-time:
    • Site-wide: 1,037
    • In genomics: 94
  • Year to date:
    • Site-wide: 2,077
  • Since beginning of last month:
    • Site-wide: 4,074

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

genetics more details view paper
  • Downloaded 3,261 times
  • Download rankings, all-time:
    • Site-wide: 3,657
    • In genetics: 150
  • Year to date:
    • Site-wide: 38,989
  • Since beginning of last month:
    • Site-wide: 79,986

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

genomics more details view paper
  • Downloaded 3,247 times
  • Download rankings, all-time:
    • Site-wide: 3,679
    • In genomics: 415
  • Year to date:
    • Site-wide: 56,193
  • Since beginning of last month:
    • Site-wide: 37,962

Genetic analysis of over one million people identifies 535 novel loci for blood pressure.

genetics more details view paper
  • Downloaded 3,082 times
  • Download rankings, all-time:
    • Site-wide: 3,953
    • In genetics: 168
  • Year to date:
    • Site-wide: 52,684
  • Since beginning of last month:
    • Site-wide: 66,454

Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes

genomics more details view paper
  • Downloaded 2,882 times
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    • Site-wide: 4,330
    • In genomics: 486
  • Year to date:
    • Site-wide: 7,275
  • Since beginning of last month:
    • Site-wide: 8,486

Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations

genetics more details view paper
  • Downloaded 2,366 times
  • Download rankings, all-time:
    • Site-wide: 5,795
    • In genetics: 271
  • Year to date:
    • Site-wide: 5,433
  • Since beginning of last month:
    • Site-wide: 6,225

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

genomics more details view paper
  • Downloaded 2,092 times
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    • Site-wide: 6,936
    • In genomics: 768
  • Year to date:
    • Site-wide: 125,717
  • Since beginning of last month:
    • Site-wide: 103,246

The Polygenic and Monogenic Basis of Blood Traits and Diseases

genetic and genomic medicine more details view paper
  • Downloaded 2,006 times
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    • Site-wide: 7,364
    • In genetic and genomic medicine: 24
  • Year to date:
    • Site-wide: 21,347
  • Since beginning of last month:
    • Site-wide: 17,429

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

genetics more details view paper
  • Downloaded 1,851 times
  • Download rankings, all-time:
    • Site-wide: 8,334
    • In genetics: 391
  • Year to date:
    • Site-wide: 85,043
  • Since beginning of last month:
    • Site-wide: 81,682

Identification of type 2 diabetes loci in 433,540 East Asian individuals

genetics more details view paper
  • Downloaded 1,814 times
  • Download rankings, all-time:
    • Site-wide: 8,600
    • In genetics: 405
  • Year to date:
    • Site-wide: 31,123
  • Since beginning of last month:
    • Site-wide: 26,145

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

genetics more details view paper
  • Downloaded 1,717 times
  • Download rankings, all-time:
    • Site-wide: 9,354
    • In genetics: 447
  • Year to date:
    • Site-wide: 79,904
  • Since beginning of last month:
    • Site-wide: 81,700

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

genetics more details view paper
  • Downloaded 1,660 times
  • Download rankings, all-time:
    • Site-wide: 9,826
    • In genetics: 469
  • Year to date:
    • Site-wide: 61,842
  • Since beginning of last month:
    • Site-wide: 40,345

Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries

genetics more details view paper
  • Downloaded 1,650 times
  • Download rankings, all-time:
    • Site-wide: 9,913
    • In genetics: 477
  • Year to date:
    • Site-wide: 76,351
  • Since beginning of last month:
    • Site-wide: 65,825

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

genetics more details view paper
  • Downloaded 1,471 times
  • Download rankings, all-time:
    • Site-wide: 11,676
    • In genetics: 569
  • Year to date:
    • Site-wide: 85,440
  • Since beginning of last month:
    • Site-wide: 100,123

Genotyping common, large structural variations in 5,202 genomes using pangenomes, the Giraffe mapper, and the vg toolkit

bioinformatics more details view paper
  • Downloaded 1,446 times
  • Download rankings, all-time:
    • Site-wide: 11,983
    • In bioinformatics: 1,471
  • Year to date:
    • Site-wide: 1,812
  • Since beginning of last month:
    • Site-wide: 2,874

Genetic Determinants of Cortical Structure (Thickness, Surface Area and Volumes) among Disease Free Adults in the CHARGE Consortium

genetics more details view paper
  • Downloaded 1,442 times
  • Download rankings, all-time:
    • Site-wide: 12,041
    • In genetics: 589
  • Year to date:
    • Site-wide: 29,303
  • Since beginning of last month:
    • Site-wide: 22,967

Population sequencing data reveal a compendium of mutational processes in human germline

genetics more details view paper
  • Downloaded 1,291 times
  • Download rankings, all-time:
    • Site-wide: 14,275
    • In genetics: 704
  • Year to date:
    • Site-wide: 19,763
  • Since beginning of last month:
    • Site-wide: 14,109

Genetic architecture of gene expression traits across diverse populations

genomics more details view paper
  • Downloaded 1,215 times
  • Download rankings, all-time:
    • Site-wide: 15,663
    • In genomics: 1,616
  • Year to date:
    • Site-wide: 92,727
  • Since beginning of last month:
    • Site-wide: 98,209

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

genetics more details view paper
  • Downloaded 1,198 times
  • Download rankings, all-time:
    • Site-wide: 15,978
    • In genetics: 792
  • Year to date:
    • Site-wide: 49,930
  • Since beginning of last month:
    • Site-wide: 65,674

Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

genetics more details view paper
  • Downloaded 1,165 times
  • Download rankings, all-time:
    • Site-wide: 16,673
    • In genetics: 817
  • Year to date:
    • Site-wide: 5,865
  • Since beginning of last month:
    • Site-wide: 5,271

Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

genetic and genomic medicine more details view paper
  • Downloaded 1,083 times
  • Download rankings, all-time:
    • Site-wide: 18,544
    • In genetic and genomic medicine: 64
  • Year to date:
    • Site-wide: 7,238
  • Since beginning of last month:
    • Site-wide: 7,863

A genome-wide association study for nonalcoholic fatty liver disease identifies novel genetic loci and trait-relevant candidate genes in the Million Veteran Program.

genetic and genomic medicine more details view paper
  • Downloaded 1,017 times
  • Download rankings, all-time:
    • Site-wide: 20,381
    • In genetic and genomic medicine: 69
  • Year to date:
    • Site-wide: 1,028
  • Since beginning of last month:
    • Site-wide: 3,284

Genome-wide Meta-analysis of 158,000 Individuals of European Ancestry Identifies Three Loci Associated with Chronic Back Pain

genomics more details view paper
  • Downloaded 969 times
  • Download rankings, all-time:
    • Site-wide: 21,794
    • In genomics: 2,153
  • Year to date:
    • Site-wide: 98,259
  • Since beginning of last month:
    • Site-wide: 81,544

Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation

genetics more details view paper
  • Downloaded 840 times
  • Download rankings, all-time:
    • Site-wide: 26,731
    • In genetics: 1,300
  • Year to date:
    • Site-wide: 27,056
  • Since beginning of last month:
    • Site-wide: 19,531

Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole genome sequencing studies

genetics more details view paper
  • Downloaded 839 times
  • Download rankings, all-time:
    • Site-wide: 26,786
    • In genetics: 1,302
  • Year to date:
    • Site-wide: 93,665
  • Since beginning of last month:
    • Site-wide: 99,890

Atrial Fibrillation Genetic Risk Differentiates Cardioembolic Stroke from other Stroke Subtypes

genetics more details view paper
  • Downloaded 825 times
  • Download rankings, all-time:
    • Site-wide: 27,403
    • In genetics: 1,331
  • Year to date:
    • Site-wide: 59,639
  • Since beginning of last month:
    • Site-wide: 64,857

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

genetic and genomic medicine more details view paper
  • Downloaded 811 times
  • Download rankings, all-time:
    • Site-wide: 28,075
    • In genetic and genomic medicine: 89
  • Year to date:
    • Site-wide: 25,482
  • Since beginning of last month:
    • Site-wide: 19,103

The Trans-Ancestral Genomic Architecture of Glycaemic Traits

genetics more details view paper
  • Downloaded 794 times
  • Download rankings, all-time:
    • Site-wide: 28,939
    • In genetics: 1,404
  • Year to date:
    • Site-wide: 13,179
  • Since beginning of last month:
    • Site-wide: 8,900

Novel blood pressure locus and gene discovery using GWAS and expression datasets from blood and the kidney

genomics more details view paper
  • Downloaded 751 times
  • Download rankings, all-time:
    • Site-wide: 31,271
    • In genomics: 2,798
  • Year to date:
    • Site-wide: 92,614
  • Since beginning of last month:
    • Site-wide: 103,017

Loss-of-function genomic variants with impact on liver-related blood traits highlight potential therapeutic targets for cardiovascular disease

genomics more details view paper
  • Downloaded 742 times
  • Download rankings, all-time:
    • Site-wide: 31,784
    • In genomics: 2,829
  • Year to date:
    • Site-wide: 79,256
  • Since beginning of last month:
    • Site-wide: 116,845

Trans-ethnic genome-wide association study provides insight into effector genes and molecular mechanisms for kidney function and highlights a causal effect on kidney-specific disease aetiologies

genetics more details view paper
  • Downloaded 713 times
  • Download rankings, all-time:
    • Site-wide: 33,565
    • In genetics: 1,633
  • Year to date:
    • Site-wide: 119,846
  • Since beginning of last month:
    • Site-wide: 104,695

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

genomics more details view paper
  • Downloaded 667 times
  • Download rankings, all-time:
    • Site-wide: 36,801
    • In genomics: 3,140
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    • Site-wide: 73,511
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    • Site-wide: 101,791

Rare coding variants in 35 genes associate with circulating lipid levels: a multi-ancestry analysis of 170,000 exomes

genetics more details view paper
  • Downloaded 617 times
  • Download rankings, all-time:
    • Site-wide: 40,669
    • In genetics: 1,941
  • Year to date:
    • Site-wide: 4,690
  • Since beginning of last month:
    • Site-wide: 13,181

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction

genetics more details view paper
  • Downloaded 613 times
  • Download rankings, all-time:
    • Site-wide: 41,009
    • In genetics: 1,949
  • Year to date:
    • Site-wide: 73,733
  • Since beginning of last month:
    • Site-wide: 63,939

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

genetics more details view paper
  • Downloaded 607 times
  • Download rankings, all-time:
    • Site-wide: 41,525
    • In genetics: 1,976
  • Year to date:
    • Site-wide: 108,324
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    • Site-wide: 81,694

Discovering patterns of pleiotropy in genome-wide association studies

genetics more details view paper
  • Downloaded 579 times
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    • Site-wide: 43,973
    • In genetics: 2,068
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    • Site-wide: 113,088
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Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

genetics more details view paper
  • Downloaded 570 times
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    • Site-wide: 44,835
    • In genetics: 2,114
  • Year to date:
    • Site-wide: 89,839
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    • Site-wide: 74,346

A Comprehensive Evaluation of the Genetic Architecture of Sudden Cardiac Arrest

genetics more details view paper
  • Downloaded 564 times
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    • Site-wide: 45,490
    • In genetics: 2,143
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    • Site-wide: 113,620
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    • Site-wide: 125,689

Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile

genomics more details view paper
  • Downloaded 506 times
  • Download rankings, all-time:
    • Site-wide: 51,792
    • In genomics: 4,020
  • Year to date:
    • Site-wide: 119,149
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    • Site-wide: 119,941

Whole genome sequencing association analysis of quantitative red blood cell phenotypes: the NHLBI TOPMed program

hematology more details view paper
  • Downloaded 467 times
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    • Site-wide: 56,700
    • In hematology: 34
  • Year to date:
    • Site-wide: 6,130
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    • Site-wide: 10,408

Large Meta-Analysis in the CHARGE Consortium Provides Evidence For an Association of Serum Vitamin D With Pulmonary Function

epidemiology more details view paper
  • Downloaded 438 times
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    • Site-wide: 60,555
    • In epidemiology: 2,614
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    • Site-wide: 110,550
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    • Site-wide: 99,044

Whole-Genome Association Analyses of Sleep-disordered Breathing Phenotypes in the NHLBI TOPMed Program

genetics more details view paper
  • Downloaded 437 times
  • Download rankings, all-time:
    • Site-wide: 60,740
    • In genetics: 2,831
  • Year to date:
    • Site-wide: 73,827
  • Since beginning of last month:
    • Site-wide: 72,897

Collaborative Cohort of Cohorts for COVID-19 Research (C4R) Study: Study Design

epidemiology more details view paper
  • Downloaded 408 times
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    • Site-wide: 65,192
    • In epidemiology: 2,779
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    • Site-wide: 3,637
  • Since beginning of last month:
    • Site-wide: 938

Impact of rare and common genetic variants on diabetes diagnosis by hemoglobin A1c in multi-ancestry cohorts: The Trans-Omics for Precision Medicine Program.

genetics more details view paper
  • Downloaded 396 times
  • Download rankings, all-time:
    • Site-wide: 67,040
    • In genetics: 3,093
  • Year to date:
    • Site-wide: 59,013
  • Since beginning of last month:
    • Site-wide: 64,396

Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits

genetics more details view paper
  • Downloaded 396 times
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    • Site-wide: 67,094
    • In genetics: 3,089
  • Year to date:
    • Site-wide: 69,916
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    • Site-wide: 69,707

Multi-ethnic genome-wide association study of decomposed cardioelectric phenotypes illustrates strategies to identify and characterize evidence of shared genetic effects for complex traits

epidemiology more details view paper
  • Downloaded 368 times
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    • Site-wide: 71,751
    • In epidemiology: 3,010
  • Year to date:
    • Site-wide: 85,101
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    • Site-wide: 64,265

Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Humans and Mice

physiology more details view paper
  • Downloaded 364 times
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    • Site-wide: 72,481
    • In physiology: 545
  • Year to date:
    • Site-wide: 68,399
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    • Site-wide: 91,297

Novel DNA methylation sites of glucose and insulin homeostasis: an integrative cross-omics analysis

genomics more details view paper
  • Downloaded 352 times
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    • Site-wide: 74,614
    • In genomics: 5,060
  • Year to date:
    • Site-wide: 126,048
  • Since beginning of last month:
    • Site-wide: 122,834

Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American specific associations

genomics more details view paper
  • Downloaded 323 times
  • Download rankings, all-time:
    • Site-wide: 80,116
    • In genomics: 5,258
  • Year to date:
    • Site-wide: 112,753
  • Since beginning of last month:
    • Site-wide: 105,977

Rare Non-coding Variation Identified by Large Scale Whole Genome Sequencing Reveals Unexplained Heritability of Type 2 Diabetes: Trans-Omics for Precision Medicine (TOPMed) Program

genetic and genomic medicine more details view paper
  • Downloaded 320 times
  • Download rankings, all-time:
    • Site-wide: 80,733
    • In genetic and genomic medicine: 283
  • Year to date:
    • Site-wide: 22,307
  • Since beginning of last month:
    • Site-wide: 18,361

Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

epidemiology more details view paper
  • Downloaded 301 times
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    • Site-wide: 84,638
    • In epidemiology: 3,478
  • Year to date:
    • Site-wide: 74,255
  • Since beginning of last month:
    • Site-wide: 73,869

A system for phenotype harmonization in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program

genetics more details view paper
  • Downloaded 292 times
  • Download rankings, all-time:
    • Site-wide: 86,359
    • In genetics: 3,919
  • Year to date:
    • Site-wide: 46,720
  • Since beginning of last month:
    • Site-wide: None

Association of mitochondrial DNA copy number with cardiometabolic diseases in a large cross-sectional study of multiple ancestries

epidemiology more details view paper
  • Downloaded 291 times
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    • Site-wide: 86,716
    • In epidemiology: 3,563
  • Year to date:
    • Site-wide: 38,726
  • Since beginning of last month:
    • Site-wide: 52,339

Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization

genetics more details view paper
  • Downloaded 268 times
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    • Site-wide: 91,651
    • In genetics: 4,136
  • Year to date:
    • Site-wide: 121,590
  • Since beginning of last month:
    • Site-wide: 105,958

GWAS of QRS Duration Identifies New Loci Specific to Hispanic/Latino Populations

genetics more details view paper
  • Downloaded 259 times
  • Download rankings, all-time:
    • Site-wide: 93,690
    • In genetics: 4,211
  • Year to date:
    • Site-wide: 129,587
  • Since beginning of last month:
    • Site-wide: 125,806

Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

genomics more details view paper
  • Downloaded 210 times
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    • Site-wide: 104,515
    • In genomics: 6,111
  • Year to date:
    • Site-wide: 95,502
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    • Site-wide: 69,827

Transcriptional survey of peripheral blood links lower oxygen saturation during sleep with reduced expressions of CD1D and RAB20 that is reversed by CPAP therapy

genetic and genomic medicine more details view paper
  • Downloaded 188 times
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    • Site-wide: 109,159
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    • Site-wide: 104,595
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    • Site-wide: 69,945

Bidirectional Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of intermediate potential

genetic and genomic medicine more details view paper
  • Downloaded 183 times
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    • Site-wide: 110,264
    • In genetic and genomic medicine: 481
  • Year to date:
    • Site-wide: 11,503
  • Since beginning of last month:
    • Site-wide: 2,912

Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program

genetic and genomic medicine more details view paper
  • Downloaded 178 times
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    • Site-wide: 111,282
    • In genetic and genomic medicine: 494
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    • Site-wide: 11,897
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    • Site-wide: 32,124

BinomiRare: A carriers-only test for association of rare genetic variants with a binary outcome for mixed models and any case-control proportion

genetic and genomic medicine more details view paper
  • Downloaded 171 times
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    • Site-wide: 112,774
    • In genetic and genomic medicine: 509
  • Year to date:
    • Site-wide: 12,555
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    • Site-wide: 36,352

Mitochondrial DNA Copy Number and Incident Atrial Fibrillation

genetics more details view paper
  • Downloaded 161 times
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    • Site-wide: 114,815
    • In genetics: 4,972
  • Year to date:
    • Site-wide: 115,089
  • Since beginning of last month:
    • Site-wide: 113,165

A long noncoding RNA, LOC157273, is the effector transcript at the chromosome 8p23.1-PPP1R3B metabolic traits and type 2 diabetes risk locus

genomics more details view paper
  • Downloaded 160 times
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    • Site-wide: 115,154
    • In genomics: 6,425
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    • Site-wide: 109,044
  • Since beginning of last month:
    • Site-wide: 120,827

Genome-wide association study of body fat distribution traits in Hispanics/Latinos from the HCHS/SOL Study

genetic and genomic medicine more details view paper
  • Downloaded 81 times
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    • Site-wide: 129,607
    • In genetic and genomic medicine: 633
  • Year to date:
    • Site-wide: 30,610
  • Since beginning of last month:
    • Site-wide: 20,423

Benchmarking Association Analyses of Continuous Exposures with RNA-seq in Observational Studies

bioinformatics more details view paper
  • Downloaded 53 times
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    • Site-wide: 132,599
    • In bioinformatics: 10,379
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    • Site-wide: 46,498
  • Since beginning of last month:
    • Site-wide: 61,166

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