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Author: Edwin Cuppen

Rankings

  • All-time downloads: 35,326 (rank: 1,201 out of 397,248)
  • Categories:
    • bioinformatics: 3,983 (rank: 2,463 out of 33,885)
    • cancer biology: 14,372 (rank: 71 out of 27,563)
    • cell biology: 8,505 (rank: 256 (tie) out of 29,809)
    • developmental biology: 521 (rank: 6,332 (tie) out of 15,422)
    • genomics: 6,797 (rank: 2,428 out of 42,185)
    • molecular biology: 1,148 (rank: 3,259 (tie) out of 20,994)

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Preprints

Pan-cancer whole genome analyses of metastatic solid tumors

cancer biology more details view paper
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    • In cancer biology: 15 out of 3,289
  • Year to date:
    • Site-wide: 4,669 out of 93,037
  • Since beginning of last month:
    • Site-wide: 8,452 out of 93,037

Long-term expanding human airway organoids for disease modelling.

cell biology more details view paper
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    • Site-wide: 744 out of 93,037
    • In cell biology: 17 out of 4,791
  • Year to date:
    • Site-wide: 3,214 out of 93,037
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    • Site-wide: 9,255 out of 93,037

SARS-CoV-2 Productively Infects Human Gut Enterocytes

cell biology more details view paper
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    • In cell biology: 44 out of 4,791
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    • Site-wide: 2,672 out of 93,037

Tumor mutational landscape is a record of the pre-malignant state

genomics more details view paper
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    • In genomics: 349 out of 5,863
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    • Site-wide: 9,420 out of 93,037
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    • Site-wide: 18,859 out of 93,037

A deep learning system can accurately classify primary and metastatic cancers based on patterns of passenger mutations

cancer biology more details view paper
  • Downloaded 3,071 times
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    • Site-wide: 1,869 out of 93,037
    • In cancer biology: 49 out of 3,289
  • Year to date:
    • Site-wide: 9,771 out of 93,037
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    • Site-wide: 24,164 out of 93,037

MutationalPatterns: comprehensive genome-wide analysis of mutational processes

bioinformatics more details view paper
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    • Site-wide: 2,596 out of 93,037
    • In bioinformatics: 465 out of 8,711
  • Year to date:
    • Site-wide: 15,674 out of 93,037
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    • Site-wide: 11,578 out of 93,037

Mapping And Phasing Of Structural Variation In Patient Genomes Using Nanopore Sequencing

genomics more details view paper
  • Downloaded 2,418 times
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    • Site-wide: 2,791 out of 93,037
    • In genomics: 522 out of 5,863
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    • Site-wide: 60,490 out of 93,037
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    • Site-wide: 46,276 out of 93,037

The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact

cancer biology more details view paper
  • Downloaded 1,626 times
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    • Site-wide: 5,356 out of 93,037
    • In cancer biology: 129 out of 3,289
  • Year to date:
    • Site-wide: 18,411 out of 93,037
  • Since beginning of last month:
    • Site-wide: 14,953 out of 93,037

Learning mutational signatures and their multidimensional genomic properties with TensorSignatures

cancer biology more details view paper
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    • Site-wide: 6,452 out of 93,037
    • In cancer biology: 168 out of 3,289
  • Year to date:
    • Site-wide: 2,148 out of 93,037
  • Since beginning of last month:
    • Site-wide: 2,550 out of 93,037

Pan-cancer landscape of homologous recombination deficiency

cancer biology more details view paper
  • Downloaded 1,346 times
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    • Site-wide: 7,340 out of 93,037
    • In cancer biology: 199 out of 3,289
  • Year to date:
    • Site-wide: 1,135 out of 93,037
  • Since beginning of last month:
    • Site-wide: 1,795 out of 93,037

GRIDSS, PURPLE, LINX: Unscrambling the tumor genome via integrated analysis of structural variation and copy number

bioinformatics more details view paper
  • Downloaded 1,309 times
  • Download rankings, all-time:
    • Site-wide: 7,717 out of 93,037
    • In bioinformatics: 1,330 out of 8,711
  • Year to date:
    • Site-wide: 3,455 out of 93,037
  • Since beginning of last month:
    • Site-wide: 8,529 out of 93,037

Deficiency of nucleotide excision repair explains mutational signature observed in cancer

molecular biology more details view paper
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    • Site-wide: 9,598 out of 93,037
    • In molecular biology: 328 out of 3,187
  • Year to date:
    • Site-wide: 36,158 out of 93,037
  • Since beginning of last month:
    • Site-wide: 58,801 out of 93,037

5-Fluorouracil treatment induces characteristic T>G mutations in human cancer

cancer biology more details view paper
  • Downloaded 576 times
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    • Site-wide: 27,388 out of 93,037
    • In cancer biology: 864 out of 3,289
  • Year to date:
    • Site-wide: 61,849 out of 93,037
  • Since beginning of last month:
    • Site-wide: 89,857 out of 93,037

Sperm DNA damage causes genomic instability in early embryonic development

developmental biology more details view paper
  • Downloaded 521 times
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    • Site-wide: 31,130 out of 93,037
    • In developmental biology: 870 out of 2,758
  • Year to date:
    • Site-wide: 23,235 out of 93,037
  • Since beginning of last month:
    • Site-wide: 70,011 out of 93,037

Mutational impact of culturing human pluripotent and adult stem cells

genomics more details view paper
  • Downloaded 480 times
  • Download rankings, all-time:
    • Site-wide: 34,402 out of 93,037
    • In genomics: 3,356 out of 5,863
  • Year to date:
    • Site-wide: 48,389 out of 93,037
  • Since beginning of last month:
    • Site-wide: 43,040 out of 93,037

Early divergence of mutational mechanisms drives genetic heterogeneity of fetal tissues

genomics more details view paper
  • Downloaded 420 times
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    • Site-wide: 40,136 out of 93,037
    • In genomics: 3,711 out of 5,863
  • Year to date:
    • Site-wide: 77,617 out of 93,037
  • Since beginning of last month:
    • Site-wide: 78,543 out of 93,037

A system-wide approach to monitor responses to synergistic BRAF and EGFR inhibition in colorectal cancer cells

cancer biology more details view paper
  • Downloaded 408 times
  • Download rankings, all-time:
    • Site-wide: 41,430 out of 93,037
    • In cancer biology: 1,326 out of 3,289
  • Year to date:
    • Site-wide: 76,132 out of 93,037
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    • Site-wide: 44,379 out of 93,037

Prioritization of genes driving congenital phenotypes of patients with de novo genomic structural variants

genomics more details view paper
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    • Site-wide: 54,764 out of 93,037
    • In genomics: 4,454 out of 5,863
  • Year to date:
    • Site-wide: 63,267 out of 93,037
  • Since beginning of last month:
    • Site-wide: 48,995 out of 93,037

Mutational impact of chronic alcohol use on stem cells in cirrhotic liver

cancer biology more details view paper
  • Downloaded 291 times
  • Download rankings, all-time:
    • Site-wide: 56,715 out of 93,037
    • In cancer biology: 1,841 out of 3,289
  • Year to date:
    • Site-wide: 48,793 out of 93,037
  • Since beginning of last month:
    • Site-wide: 42,603 out of 93,037

GRIDSS2: harnessing the power of phasing and single breakends in somatic structural variant detection

bioinformatics more details view paper
  • Downloaded 150 times
  • Download rankings, all-time:
    • Site-wide: 80,139 out of 93,037
    • In bioinformatics: 7,831 out of 8,711
  • Year to date:
    • Site-wide: 28,801 out of 93,037
  • Since beginning of last month:
    • Site-wide: 2,079 out of 93,037

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