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Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 65,152 bioRxiv papers from 288,686 authors.

Author: David E Root

  • Most recently observed institution: Broad Institute of Harvard and MIT

Rankings

  • All-time downloads: 25,951 (rank: 801 out of 288,686)
  • Categories:
    • bioinformatics: 629 (rank: 11,673 (tie) out of 25,180)
    • cancer biology: 5,333 (rank: 191 out of 17,977)
    • genomics: 19,989 (rank: 333 out of 32,860)

Downloads per author, site-wide

Preprints

Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus

genomics more details view paper

No bioRxiv download data for this paper yet.

A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles

genomics more details view paper
  • Downloaded 8,258 times
  • Download rankings, all-time:
    • Site-wide: 166 out of 65,152
    • In genomics: 51 out of 4,449
  • Year to date:
    • Site-wide: 2,142 out of 65,152
  • Since beginning of last month:
    • Site-wide: 7,401 out of 65,152

Up, down, and out: optimized libraries for CRISPRa, CRISPRi, and CRISPR-knockout genetic screens

genomics more details view paper
  • Downloaded 5,605 times
  • Download rankings, all-time:
    • Site-wide: 353 out of 65,152
    • In genomics: 90 out of 4,449
  • Year to date:
    • Site-wide: 320 out of 65,152
  • Since beginning of last month:
    • Site-wide: 1,779 out of 65,152

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

genomics more details view paper
  • Downloaded 2,558 times
  • Download rankings, all-time:
    • Site-wide: 1,497 out of 65,152
    • In genomics: 338 out of 4,449
  • Year to date:
    • Site-wide: 2,444 out of 65,152
  • Since beginning of last month:
    • Site-wide: 11,569 out of 65,152

Computational correction of copy-number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells

genomics more details view paper
  • Downloaded 2,044 times
  • Download rankings, all-time:
    • Site-wide: 2,261 out of 65,152
    • In genomics: 478 out of 4,449
  • Year to date:
    • Site-wide: 13,456 out of 65,152
  • Since beginning of last month:
    • Site-wide: 8,997 out of 65,152

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

cancer biology more details view paper
  • Downloaded 1,896 times
  • Download rankings, all-time:
    • Site-wide: 2,559 out of 65,152
    • In cancer biology: 62 out of 2,169
  • Year to date:
    • Site-wide: 704 out of 65,152
  • Since beginning of last month:
    • Site-wide: 3,179 out of 65,152

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency datasets

cancer biology more details view paper
  • Downloaded 1,579 times
  • Download rankings, all-time:
    • Site-wide: 3,484 out of 65,152
    • In cancer biology: 88 out of 2,169
  • Year to date:
    • Site-wide: 749 out of 65,152
  • Since beginning of last month:
    • Site-wide: 3,393 out of 65,152

Mapping protein function with CRISPR/Cas9-mediated mutagenesis

genomics more details view paper
  • Downloaded 1,097 times
  • Download rankings, all-time:
    • Site-wide: 6,439 out of 65,152
    • In genomics: 1,055 out of 4,449
  • Year to date:
    • Site-wide: 53,594 out of 65,152
  • Since beginning of last month:
    • Site-wide: 51,279 out of 65,152

Acquired FGFR and FGF alterations confer resistance to estrogen receptor (ER) targeted therapy in ER+ metastatic breast cancer

cancer biology more details view paper
  • Downloaded 789 times
  • Download rankings, all-time:
    • Site-wide: 10,784 out of 65,152
    • In cancer biology: 309 out of 2,169
  • Year to date:
    • Site-wide: 2,610 out of 65,152
  • Since beginning of last month:
    • Site-wide: 2,535 out of 65,152

Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines

cancer biology more details view paper
  • Downloaded 632 times
  • Download rankings, all-time:
    • Site-wide: 14,815 out of 65,152
    • In cancer biology: 441 out of 2,169
  • Year to date:
    • Site-wide: 3,860 out of 65,152
  • Since beginning of last month:
    • Site-wide: 2,112 out of 65,152

Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map

bioinformatics more details view paper
  • Downloaded 629 times
  • Download rankings, all-time:
    • Site-wide: 14,929 out of 65,152
    • In bioinformatics: 2,355 out of 6,446
  • Year to date:
    • Site-wide: 55,740 out of 65,152
  • Since beginning of last month:
    • Site-wide: 41,444 out of 65,152

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

cancer biology more details view paper
  • Downloaded 437 times
  • Download rankings, all-time:
    • Site-wide: 23,770 out of 65,152
    • In cancer biology: 732 out of 2,169
  • Year to date:
    • Site-wide: 10,938 out of 65,152
  • Since beginning of last month:
    • Site-wide: 47,156 out of 65,152

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis

genomics more details view paper
  • Downloaded 427 times
  • Download rankings, all-time:
    • Site-wide: 24,385 out of 65,152
    • In genomics: 2,615 out of 4,449
  • Year to date:
    • Site-wide: 23,587 out of 65,152
  • Since beginning of last month:
    • Site-wide: 53,867 out of 65,152

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