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Rxivist combines preprints from bioRxiv with data from Twitter to help you find the papers being discussed in your field. Currently indexing 72,967 bioRxiv papers from 317,668 authors.

Author: David E Root

  • Most recently observed institution: Broad Institute of Harvard and MIT

Rankings

  • All-time downloads: 28,066 (rank: 846 out of 317,952)
  • Categories:
    • bioinformatics: 653 (rank: 12,857 (tie) out of 27,595)
    • cancer biology: 6,569 (rank: 172 out of 20,911)
    • genomics: 20,844 (rank: 341 out of 35,549)

Downloads per author, site-wide

Preprints

A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles

genomics more details view paper
  • Downloaded 8,412 times
  • Download rankings, all-time:
    • Site-wide: 196 out of 73,028
    • In genomics: 54 out of 4,850
  • Year to date:
    • Site-wide: 8,204 out of 73,028
  • Since beginning of last month:
    • Site-wide: 8,204 out of 73,028

Up, down, and out: optimized libraries for CRISPRa, CRISPRi, and CRISPR-knockout genetic screens

genomics more details view paper
  • Downloaded 5,997 times
  • Download rankings, all-time:
    • Site-wide: 361 out of 73,028
    • In genomics: 88 out of 4,850
  • Year to date:
    • Site-wide: 2,030 out of 73,028
  • Since beginning of last month:
    • Site-wide: 2,030 out of 73,028

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

genomics more details view paper
  • Downloaded 2,603 times
  • Download rankings, all-time:
    • Site-wide: 1,667 out of 73,028
    • In genomics: 367 out of 4,850
  • Year to date:
    • Site-wide: 27,874 out of 73,028
  • Since beginning of last month:
    • Site-wide: 27,874 out of 73,028

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

cancer biology more details view paper
  • Downloaded 2,125 times
  • Download rankings, all-time:
    • Site-wide: 2,418 out of 73,028
    • In cancer biology: 57 out of 2,501
  • Year to date:
    • Site-wide: 4,326 out of 73,028
  • Since beginning of last month:
    • Site-wide: 4,326 out of 73,028

Computational correction of copy-number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells

genomics more details view paper
  • Downloaded 2,119 times
  • Download rankings, all-time:
    • Site-wide: 2,426 out of 73,028
    • In genomics: 498 out of 4,850
  • Year to date:
    • Site-wide: 20,982 out of 73,028
  • Since beginning of last month:
    • Site-wide: 20,982 out of 73,028

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency datasets

cancer biology more details view paper
  • Downloaded 1,742 times
  • Download rankings, all-time:
    • Site-wide: 3,403 out of 73,028
    • In cancer biology: 85 out of 2,501
  • Year to date:
    • Site-wide: 8,734 out of 73,028
  • Since beginning of last month:
    • Site-wide: 8,734 out of 73,028

Extracting Biological Insights from the Project Achilles Genome-Scale CRISPR Screens in Cancer Cell Lines

cancer biology more details view paper
  • Downloaded 1,132 times
  • Download rankings, all-time:
    • Site-wide: 7,040 out of 73,028
    • In cancer biology: 189 out of 2,501
  • Year to date:
    • Site-wide: 626 out of 73,028
  • Since beginning of last month:
    • Site-wide: 626 out of 73,028

Mapping protein function with CRISPR/Cas9-mediated mutagenesis

genomics more details view paper
  • Downloaded 1,122 times
  • Download rankings, all-time:
    • Site-wide: 7,149 out of 73,028
    • In genomics: 1,144 out of 4,850
  • Year to date:
    • Site-wide: 49,781 out of 73,028
  • Since beginning of last month:
    • Site-wide: 49,781 out of 73,028

Acquired FGFR and FGF alterations confer resistance to estrogen receptor (ER) targeted therapy in ER+ metastatic breast cancer

cancer biology more details view paper
  • Downloaded 1,084 times
  • Download rankings, all-time:
    • Site-wide: 7,526 out of 73,028
    • In cancer biology: 202 out of 2,501
  • Year to date:
    • Site-wide: 4,827 out of 73,028
  • Since beginning of last month:
    • Site-wide: 4,827 out of 73,028

Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map

bioinformatics more details view paper
  • Downloaded 653 times
  • Download rankings, all-time:
    • Site-wide: 16,515 out of 73,028
    • In bioinformatics: 2,541 out of 7,133
  • Year to date:
    • Site-wide: 62,650 out of 73,028
  • Since beginning of last month:
    • Site-wide: 62,650 out of 73,028

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

cancer biology more details view paper
  • Downloaded 486 times
  • Download rankings, all-time:
    • Site-wide: 24,586 out of 73,028
    • In cancer biology: 765 out of 2,501
  • Year to date:
    • Site-wide: 31,333 out of 73,028
  • Since beginning of last month:
    • Site-wide: 31,333 out of 73,028

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis

genomics more details view paper
  • Downloaded 452 times
  • Download rankings, all-time:
    • Site-wide: 26,794 out of 73,028
    • In genomics: 2,817 out of 4,850
  • Year to date:
    • Site-wide: 43,447 out of 73,028
  • Since beginning of last month:
    • Site-wide: 43,447 out of 73,028

Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus

genomics more details view paper
  • Downloaded 139 times
  • Download rankings, all-time:
    • Site-wide: 63,417 out of 73,028
    • In genomics: 4,574 out of 4,850
  • Year to date:
    • Site-wide: 19,756 out of 73,028
  • Since beginning of last month:
    • Site-wide: 19,756 out of 73,028

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