Author: William C. Hahn

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Preprints

Genome-scale genetic screening identifies PRMT1 as a critical vulnerability in castration-resistant prostate cancer

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Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

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Computational correction of copy-number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells

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A comparative analysis of network mutation burdens across 21 tumor types augments discovery from cancer genomes

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Agreement between two large pan-cancer CRISPR-Cas9 gene dependency datasets

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Global computational alignment of tumor and cell line transcriptional profiles

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Expanding discovery from cancer genomes by integrating protein network analyses with in vivo tumorigenesis assays

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Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

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STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation

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