Author: David A. Wheeler

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Preprints

The Repertoire of Mutational Signatures in Human Cancer

• Downloaded 18,476 times
• Download rankings, all-time:
  • Site-wide: 327
  • In cancer biology: 2
• Year to date:
  • Site-wide: 2,101
• Since beginning of last month:
  • Site-wide: 1,792

Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes

• Downloaded 5,361 times
• Download rankings, all-time:
  • Site-wide: 1,580
  • In genomics: 161
• Year to date:
  • Site-wide: 12,023
• Since beginning of last month:
  • Site-wide: 10,236

Mutation signatures reveal biological processes in human cancer

• Downloaded 2,498 times
• Download rankings, all-time:
  • Site-wide: 4,709
  • In genomics: 570
• Year to date:
  • Site-wide: 85,581
• Since beginning of last month:
  • Site-wide: 59,528

A Comprehensive Assessment of Somatic Mutation Calling in Cancer Genomes

• Downloaded 2,388 times
• Download rankings, all-time:
  • Site-wide: 5,055
  • In genomics: 616
• Year to date:
  • Site-wide: 116,185
• Since beginning of last month:
  • Site-wide: 65,575

A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

• Downloaded 2,137 times
• Download rankings, all-time:
  • Site-wide: 5,935
  • In genomics: 700
• Year to date:
  • Site-wide: 85,891
• Since beginning of last month:
  • Site-wide: 53,321

Genomic profiling of childhood tumor patient-derived xenograft models to enable rational clinical trial design

• Downloaded 1,821 times
• Download rankings, all-time:
  • Site-wide: 7,496
  • In genomics: 854
• Year to date:
  • Site-wide: 12,890
• Since beginning of last month:
  • Site-wide: 16,913

Pathway and network analysis of more than 2,500 whole cancer genomes

• Downloaded 1,551 times
• Download rankings, all-time:
  • Site-wide: 9,619
  • In cancer biology: 188
• Year to date:
  • Site-wide: 92,709
• Since beginning of last month:
  • Site-wide: 50,007

Accounting for tumor heterogeneity using a sample-specific error model improves sensitivity and specificity in mutation calling for sequencing data

• Downloaded 696 times
• Download rankings, all-time:
  • Site-wide: 30,963
  • In bioinformatics: 3,568
• Year to date:
  • Site-wide: 108,279
• Since beginning of last month:
  • Site-wide: 102,744

Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors

• Downloaded 471 times
• Download rankings, all-time:
  • Site-wide: 50,368
  • In cancer biology: 1,402
• Year to date:
  • Site-wide: 109,920
• Since beginning of last month:
  • Site-wide: 108,282