Author: Kenneth S Kendler

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Preprints

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

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Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders.

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Contrasting regional architectures of schizophrenia and other complex diseases using fast variance components analysis

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Haplotypes of common SNPs can explain missing heritability of complex diseases

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Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities

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A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

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Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

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Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

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Polygenic prediction of the phenome, across ancestry, in emerging adulthood

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Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

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Evidence of causal effect of major depression on alcohol dependence: Findings from the Psychiatric Genomics Consortium

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Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms

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Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies

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Identification of de novo mutations in prenatal neurodevelopment-associated genes in schizophrenia in two Han Chinese patient-sibling family-based cohorts

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  • In psychiatry and clinical psychology: 116
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Proof of concept: Molecular prediction of schizophrenia risk

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TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders

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  • In bioinformatics: 4,961
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FIQT: a simple, powerful method to accurately estimate effect sizes in genome scans

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Pathway-based polygenic risk implicates GO: 17144 drug metabolism in recurrent depressive disorder

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JEPEGMIX2: improved gene-level joint analysis of eQTLs in cosmopolitan cohorts.

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Increasing the resolution and precision of psychiatric GWAS by re-imputing summary statistics using a large, diverse reference panel

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The Impact on Estimations of Genetic Correlations of the Use, in Genome Wide Case-Control Studies, of Super-Normal, Unscreened and Family-History Screened Controls

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Assessing the role of long-noncoding RNA in nucleus accumbens in subjects with alcohol dependence

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Subthreshold psychosis symptoms associated with molecular genetic risk in a population-based cohort: Findings from Generation Scotland

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