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Author: Gad Getz

Rankings

  • All-time downloads: 127,780 (rank: 221 out of 398,135)
  • Categories:
    • bioinformatics: 13,674 (rank: 355 out of 33,947)
    • cancer biology: 50,339 (rank: 15 out of 27,741)
    • genetics: 9,224 (rank: 1,519 out of 36,546)
    • genomics: 54,543 (rank: 117 out of 42,280)

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Preprints

Analysis of protein-coding genetic variation in 60,706 humans

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The Repertoire of Mutational Signatures in Human Cancer

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The evolutionary history of 2,658 cancers

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The GTEx Consortium atlas of genetic regulatory effects across human tissues

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Rapid and efficient analysis of 20,000 RNA-seq samples with Toil

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The whole-genome panorama of cancer drivers

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Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes

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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

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Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

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Local genetic effects on gene expression across 44 human tissues

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Tumor mutational landscape is a record of the pre-malignant state

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Scaling computational genomics to millions of individuals with GPUs

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A comprehensive analysis of RNA sequences reveals macroscopic somatic clonal expansion across normal tissues

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A deep learning system can accurately classify primary and metastatic cancers based on patterns of passenger mutations

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    • In cancer biology: 49 out of 3,299
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Calling Somatic SNVs and Indels with Mutect2

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WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

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Thousands of novel unannotated proteins expand the MHC I immunopeptidome in cancer

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Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatment

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Large-Scale Uniform Analysis of Cancer Whole Genomes in Multiple Computing Environments

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A comparative analysis of network mutation burdens across 21 tumor types augments discovery from cancer genomes

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    • In cancer biology: 77 out of 3,299
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Passenger mutations in 2500 cancer genomes: Overall molecular functional impact and consequences

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    • In genomics: 689 out of 5,875
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Cell type specific genetic regulation of gene expression across human tissues

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    • In genomics: 706 out of 5,875
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Clustering of Type 2 Diabetes Genetic Loci by Multi-Trait Associations Identifies Disease Mechanisms and Subtypes

genetics more details view paper
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Passenger Hotspot Mutations in Cancer

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Pathway and network analysis of more than 2,500 whole cancer genomes

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    • In cancer biology: 158 out of 3,299
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FireCloud, a scalable cloud-based platform for collaborative genome analysis: Strategies for reducing and controlling costs

bioinformatics more details view paper
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Framework For Quality Assessment Of Whole Genome, Cancer Sequences

genomics more details view paper
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Expanding discovery from cancer genomes by integrating protein network analyses with in vivo tumorigenesis assays

cancer biology more details view paper
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    • In cancer biology: 408 out of 3,299
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The Tangent copy-number inference pipeline for cancer genome analyses

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    • In bioinformatics: 2,880 out of 8,742
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Detecting cancer vulnerabilities through gene networks under purifying selection in 4,700 cancer genomes

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Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes

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Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to graft-versus-leukemia

cancer biology more details view paper
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