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Author: Lawrence Shapiro

  • Most recently observed institution: Columbia University

Rankings

  • All-time downloads: 50,814 (rank: 2,766 )
  • Categories:
    • biochemistry: 1,743 (rank: 2,273 (tie) )
    • bioinformatics: 996 (rank: 14,221 (tie) )
    • biophysics: 3,360 (rank: 749 )
    • immunology: 40,579 (rank: 147 )
    • microbiology: 2,568 (rank: 5,108 (tie) )
    • neuroscience: 1,568 (rank: 14,221 (tie) )

Downloads per author, site-wide

Preprints

Increased Resistance of SARS-CoV-2 Variant P.1 to Antibody Neutralization

microbiology more details view paper

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Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

immunology more details view paper
  • Downloaded 32,905 times
  • Download rankings, all-time:
    • Site-wide: 192
    • In immunology: 9
  • Year to date:
    • Site-wide: 16
  • Since beginning of last month:
    • Site-wide: 25

Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains

immunology more details view paper
  • Downloaded 4,054 times
  • Download rankings, all-time:
    • Site-wide: 2,659
    • In immunology: 76
  • Year to date:
    • Site-wide: 3,095
  • Since beginning of last month:
    • Site-wide: 4,342

Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike

microbiology more details view paper
  • Downloaded 2,568 times
  • Download rankings, all-time:
    • Site-wide: 5,123
    • In microbiology: 307
  • Year to date:
    • Site-wide: 8,616
  • Since beginning of last month:
    • Site-wide: 12,821

Routine Single Particle CryoEM Sample and Grid Characterization by Tomography

biophysics more details view paper
  • Downloaded 2,453 times
  • Download rankings, all-time:
    • Site-wide: 5,513
    • In biophysics: 98
  • Year to date:
    • Site-wide: 52,672
  • Since beginning of last month:
    • Site-wide: 43,779

Synaptogenic activity of the axon guidance molecule Robo2 is critical for hippocampal circuit function

neuroscience more details view paper
  • Downloaded 1,471 times
  • Download rankings, all-time:
    • Site-wide: 11,678
    • In neuroscience: 1,301
  • Year to date:
    • Site-wide: 18,591
  • Since beginning of last month:
    • Site-wide: 16,088

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

immunology more details view paper
  • Downloaded 1,274 times
  • Download rankings, all-time:
    • Site-wide: 14,572
    • In immunology: 417
  • Year to date:
    • Site-wide: 29,815
  • Since beginning of last month:
    • Site-wide: 39,841

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

immunology more details view paper
  • Downloaded 1,149 times
  • Download rankings, all-time:
    • Site-wide: 17,034
    • In immunology: 496
  • Year to date:
    • Site-wide: 108,032
  • Since beginning of last month:
    • Site-wide: 119,133

Potent SARS-CoV-2 Neutralizing Antibodies Directed Against Spike N-Terminal Domain Target a Single Supersite

biochemistry more details view paper
  • Downloaded 1,137 times
  • Download rankings, all-time:
    • Site-wide: 17,265
    • In biochemistry: 352
  • Year to date:
    • Site-wide: 899
  • Since beginning of last month:
    • Site-wide: 1,830

Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

immunology more details view paper
  • Downloaded 768 times
  • Download rankings, all-time:
    • Site-wide: 30,324
    • In immunology: 873
  • Year to date:
    • Site-wide: 1,495
  • Since beginning of last month:
    • Site-wide: 4,111

Structural Basis for Accommodation of Emerging B.1.351 and B.1.1.7 Variants by Two Potent SARS-CoV-2 Neutralizing Antibodies

biochemistry more details view paper
  • Downloaded 606 times
  • Download rankings, all-time:
    • Site-wide: 41,608
    • In biochemistry: 1,041
  • Year to date:
    • Site-wide: 2,120
  • Since beginning of last month:
    • Site-wide: 1,103

The elasticity of individual protocadherin 15 molecules implicates cadherins as the gating springs for hearing

biophysics more details view paper
  • Downloaded 518 times
  • Download rankings, all-time:
    • Site-wide: 50,345
    • In biophysics: 1,706
  • Year to date:
    • Site-wide: 129,506
  • Since beginning of last month:
    • Site-wide: 123,706

Structural survey of HIV-1-neutralizing antibodies targeting Env trimer delineates epitope categories and suggests vaccine templates

bioinformatics more details view paper
  • Downloaded 508 times
  • Download rankings, all-time:
    • Site-wide: 51,547
    • In bioinformatics: 5,286
  • Year to date:
    • Site-wide: 72,816
  • Since beginning of last month:
    • Site-wide: 78,184

cAb-Rep: A Database of Curated Antibody Repertoires for Exploring antibody diversity and Predicting Antibody Prevalence

bioinformatics more details view paper
  • Downloaded 488 times
  • Download rankings, all-time:
    • Site-wide: 53,936
    • In bioinformatics: 5,500
  • Year to date:
    • Site-wide: 50,748
  • Since beginning of last month:
    • Site-wide: 45,184

Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class

immunology more details view paper
  • Downloaded 429 times
  • Download rankings, all-time:
    • Site-wide: 61,914
    • In immunology: 1,721
  • Year to date:
    • Site-wide: 3,382
  • Since beginning of last month:
    • Site-wide: 8,020

DIP/Dpr interactions and the evolutionary design of specificity in protein families

biophysics more details view paper
  • Downloaded 301 times
  • Download rankings, all-time:
    • Site-wide: 84,482
    • In biophysics: 3,222
  • Year to date:
    • Site-wide: 96,484
  • Since beginning of last month:
    • Site-wide: 112,651

Affinity Requirements For Control Of Synaptic Targeting And Neuronal Cell Survival By Heterophilic IgSF Cell Adhesion Molecules

neuroscience more details view paper
  • Downloaded 97 times
  • Download rankings, all-time:
    • Site-wide: 127,157
    • In neuroscience: 19,496
  • Year to date:
    • Site-wide: 25,193
  • Since beginning of last month:
    • Site-wide: 27,697

Cadherin-11 dimerization multi-site kinetics: combined partial unfolding and strand-swapping

biophysics more details view paper
  • Downloaded 88 times
  • Download rankings, all-time:
    • Site-wide: 128,618
    • In biophysics: 4,965
  • Year to date:
    • Site-wide: 53,204
  • Since beginning of last month:
    • Site-wide: 61,803

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