Author: Andre Franke

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Preprints

The ABO blood group locus and a chromosome 3 gene cluster associate with SARS-CoV-2 respiratory failure in an Italian-Spanish genome-wide association analysis

• Downloaded 81,709 times
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  • Site-wide: 53
  • In infectious diseases: 19
• Year to date:
  • Site-wide: 191
• Since beginning of last month:
  • Site-wide: 196

Pre-existing T cell memory as a risk factor for severe 1 COVID-19 in the elderly

• Downloaded 8,518 times
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  • Site-wide: 843
  • In allergy and immunology: 4
• Year to date:
  • Site-wide: 836
• Since beginning of last month:
  • Site-wide: 417

Association mapping of inflammatory bowel disease loci to single variant resolution

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  • Site-wide: 2,734
  • In genetics: 115
• Year to date:
  • Site-wide: 17,308
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  • Site-wide: 32,667

Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data.

• Downloaded 2,874 times
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  • Site-wide: 3,740
  • In bioinformatics: 417
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  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 104,284

Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection

• Downloaded 2,422 times
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  • Site-wide: 4,828
  • In immunology: 126
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  • Site-wide: None
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  • Site-wide: 3,141

Large-scale association analyses identify host factors influencing human gut microbiome composition

• Downloaded 1,747 times
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  • Site-wide: 7,806
  • In genetics: 394
• Year to date:
  • Site-wide: 1,378
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  • Site-wide: 1,529

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

• Downloaded 1,522 times
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  • Site-wide: 9,639
  • In genetics: 498
• Year to date:
  • Site-wide: 33,056
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  • Site-wide: 60,849

Longitudinal multi-omics analysis identifies responses of megakaryocytes, erythroid cells and plasmablasts as hallmarks of severe COVID-19 trajectories

• Downloaded 1,406 times
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  • Site-wide: 10,878
  • In infectious diseases: 1,109
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  • Site-wide: None
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  • Site-wide: 7,421

Neolithic genomes reveal a distinct ancient HLA allele pool and population transformation in Europe

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  • Site-wide: 11,863
  • In evolutionary biology: 448
• Year to date:
  • Site-wide: 12,557
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  • Site-wide: 11,510

A genome-wide genetic pleiotropy approach identified shared loci between multiple system atrophy and inflammatory bowel disease

• Downloaded 894 times
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  • Site-wide: 21,332
  • In genetics: 1,080
• Year to date:
  • Site-wide: 21,439
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  • Site-wide: 40,815

Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms

• Downloaded 675 times
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  • Site-wide: 31,626
  • In microbiology: 1,845
• Year to date:
  • Site-wide: None
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  • Site-wide: 85,816

Integrating Culture-based Antibiotic Resistance Profiles with Whole-genome Sequencing Data for 11,087 Clinical Isolates

• Downloaded 673 times
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  • Site-wide: 31,728
  • In genomics: 2,875
• Year to date:
  • Site-wide: 25,550
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  • Site-wide: 62,868

Comprehensive analysis of antiviral adaptive immunity formation and reactivation down to single-cell level

• Downloaded 659 times
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  • Site-wide: 32,646
  • In immunology: 870
• Year to date:
  • Site-wide: 42,162
• Since beginning of last month:
  • Site-wide: 51,099

Genetic determinants of risk and survival in pulmonary arterial hypertension

• Downloaded 637 times
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  • Site-wide: 34,116
  • In genetics: 1,721
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  • Site-wide: None
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  • Site-wide: 107,588

Immune-related genetic enrichment in frontotemporal dementia

• Downloaded 585 times
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  • Site-wide: 38,035
  • In genetics: 1,881
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  • Site-wide: None
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  • Site-wide: 74,440

Arrhythmic gut microbiome signatures for risk profiling of Type-2 Diabetes

• Downloaded 577 times
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  • Site-wide: 38,713
  • In microbiology: 2,313
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  • Site-wide: None
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  • Site-wide: 70,524

Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset

• Downloaded 543 times
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  • Site-wide: 41,740
  • In genomics: 3,456
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  • Site-wide: None
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  • Site-wide: 77,960

Common variants in ABCG8 and TRAF3 genes confer risk for gallstone disease and gallbladder cancer in admixed Latinos with Mapuche Native American ancestry

• Downloaded 498 times
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  • Site-wide: 46,298
  • In genetics: 2,267
• Year to date:
  • Site-wide: 49,324
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  • Site-wide: 43,488

Hemibiotrophic fungal pathogen induces systemic susceptibility and systemic shifts in wheat metabolome and microbiome composition

• Downloaded 452 times
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  • Site-wide: 51,542
  • In plant biology: 1,260
• Year to date:
  • Site-wide: 37,741
• Since beginning of last month:
  • Site-wide: 46,067

ABO histo-blood groups influence gut microbiome, with causal relationship between Bacteroides and inflammatory bowel disease

• Downloaded 432 times
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  • Site-wide: 54,144
  • In gastroenterology: 42
• Year to date:
  • Site-wide: 22,718
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  • Site-wide: 15,693

GWAS of stool frequency reveals genes, pathways, and cell types relevant to human gastrointestinal motility and irritable bowel syndrome

• Downloaded 401 times
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  • Site-wide: 58,367
  • In gastroenterology: 48
• Year to date:
  • Site-wide: 20,373
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  • Site-wide: 23,752

Depletion of erythropoietic miR-486-5p and miR-451a improves detectability of rare microRNAs in peripheral blood-derived small RNA sequencing libraries

• Downloaded 317 times
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  • Site-wide: 72,062
  • In molecular biology: 2,148
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 90,331

Genetic risk for Alzheimer`s disease predicts hippocampal volume through the lifespan

• Downloaded 309 times
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  • Site-wide: 73,486
  • In neuroscience: 11,361
• Year to date:
  • Site-wide: 48,671
• Since beginning of last month:
  • Site-wide: 55,630

Identifying Crohns disease signal from variome analysis

• Downloaded 281 times
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  • Site-wide: 78,982
  • In bioinformatics: 7,231
• Year to date:
  • Site-wide: 57,119
• Since beginning of last month:
  • Site-wide: 104,386

Primate phageomes are structured by superhost phylogeny and environment

• Downloaded 247 times
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  • Site-wide: 85,953
  • In microbiology: 6,100
• Year to date:
  • Site-wide: None
• Since beginning of last month:
  • Site-wide: 86,666

TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels

• Downloaded 201 times
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  • Site-wide: 95,554
  • In genomics: 5,787
• Year to date:
  • Site-wide: 21,613
• Since beginning of last month:
  • Site-wide: 36,295

Genome-wide analysis of 944,133 individuals provides insights into the etiology of hemorrhoidal disease

• Downloaded 193 times
• Download rankings, all-time:
  • Site-wide: 97,319
  • In genetic and genomic medicine: 347
• Year to date:
  • Site-wide: 10,049
• Since beginning of last month:
  • Site-wide: 1,732

Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associations

• Downloaded 160 times
• Download rankings, all-time:
  • Site-wide: 103,699
  • In genetic and genomic medicine: 396
• Year to date:
  • Site-wide: 35,886
• Since beginning of last month:
  • Site-wide: 28,984