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Author: Alex K. Shalek

Rankings

  • All-time downloads: 44,556 (rank: 2,618 (tie) out of 510,799)
  • Categories:
    • bioengineering: 2,738 (rank: 506 out of 13,764)
    • cancer biology: 2,171 (rank: 1,840 out of 31,491)
    • genetic and genomic medicine: 1,501 (rank: 590 (tie) out of 6,821)
    • genomics: 18,593 (rank: 523 out of 45,521)
    • immunology: 14,600 (rank: 295 out of 27,749)
    • infectious diseases: 334 (rank: 24,601 (tie) out of 32,278)
    • microbiology: 2,383 (rank: 4,414 (tie) out of 52,238)
    • systems biology: 2,236 (rank: 1,514 (tie) out of 12,795)

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Preprints

Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells

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MR1-restricted MAIT cells from the human lung mucosal surface have distinct phenotypic, functional, and transcriptomic features that are preserved in HIV infection

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Systematic comparative analysis of single cell RNA-sequencing methods

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Highly Efficient, Massively-Parallel Single-Cell RNA-Seq Reveals Cellular States and Molecular Features of Human Skin Pathology

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Rewiring of the cellular and inter-cellular landscape of the human colon during ulcerative colitis

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Sensory Neurons Innervate Peripheral Lymph Nodes and Locally Regulate Gene Expression in Postsynaptic Endothelium, Stromal Cells, and Innate Leukocytes

immunology more details view paper
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T helper cells modulate intestinal stem cell renewal and differentiation

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High-throughput organoid screening enables engineering of intestinal epithelial composition

bioengineering more details view paper
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Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases

genetic and genomic medicine more details view paper
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    • In genetic and genomic medicine: 22 out of 488
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    • Site-wide: 682 out of 118,417

Single-cell analysis of upper airway cells reveals host-viral dynamics in influenza infected adults

genomics more details view paper
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    • In genomics: 1,232 out of 6,435
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Reduced cellular diversity and an altered basal progenitor cell state inform epithelial barrier dysfunction in human type 2 immunity

immunology more details view paper
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Transcriptional subtype-specific microenvironmental crosstalk and tumor cell plasticity in metastatic pancreatic cancer

cancer biology more details view paper
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    • Site-wide: 3,121 out of 118,417

Identification of a master regulator of differentiation in Toxoplasma

microbiology more details view paper
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    • In microbiology: 594 out of 9,349
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Alterations of multiple alveolar macrophage states in chronic obstructive pulmonary disease

systems biology more details view paper
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    • In systems biology: 250 out of 2,636
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Integrated Single-Cell Analysis of Multicellular Immune Dynamics during Hyper-Acute HIV-1 Infection

immunology more details view paper
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    • In immunology: 361 out of 3,302
  • Year to date:
    • Site-wide: 19,147 out of 118,417
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    • Site-wide: 57,087 out of 118,417

Single-cell profiling of Ebola virus infection in vivo reveals viral and host transcriptional dynamics

microbiology more details view paper
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    • In microbiology: 877 out of 9,349
  • Year to date:
    • Site-wide: 5,782 out of 118,417
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    • Site-wide: 7,265 out of 118,417

Linking single-cell measurements of mass, growth rate, and gene expression

bioengineering more details view paper
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    • In bioengineering: 284 out of 2,448
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Spatially-Resolved Live Cell Tagging and Isolation Using Protected Photoactivatable Cell Dyes

systems biology more details view paper
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Single-cell profiling of tuberculosis lung granulomas reveals functional lymphocyte signatures of bacterial control

immunology more details view paper
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    • In immunology: 872 out of 3,302
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Single-cell analysis reveals mechanisms of plasticity of leukemia initiating cells

cancer biology more details view paper
  • Downloaded 522 times
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    • In cancer biology: 1,159 out of 3,748
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    • Site-wide: 44,516 out of 118,417

IL-5Rα marks nasal polyp IgG4 and IgE-secreting cells in aspirin-exacerbated respiratory disease

immunology more details view paper
  • Downloaded 511 times
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    • Site-wide: 64,807 out of 118,417

Single cell profiling of COVID-19 patients: an international data resource from multiple tissues

infectious diseases more details view paper
  • Downloaded 334 times
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    • In infectious diseases: 2,443 out of 3,587
  • Year to date:
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    • Site-wide: 2,399 out of 118,417

GM-CSF differentiation of human monocytes stabilizes macrophage state via oxidative signaling

immunology more details view paper
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    • In immunology: 2,000 out of 3,302
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    • Site-wide: 3,178 out of 118,417

Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states

cancer biology more details view paper
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    • In cancer biology: 2,459 out of 3,748
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    • Site-wide: 3,687 out of 118,417

Spatiotemporal single-cell profiling of gastrointestinal GVHD reveals invasive and resident memory T cell states.

immunology more details view paper
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Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieu

immunology more details view paper
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Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice

cancer biology more details view paper
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    • In cancer biology: 3,661 out of 3,748
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